Exosome non-catalytic core subunit MTR3 YGR158C (Q27549014)

http://www.ebi.ac.uk/interpro/protein/P48240

PNPase/RNase PH domain superfamily

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P48240

Exoribonuclease, phosphorolytic domain 1, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Saccharomyces cerevisiae S288c

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48240

13 references

9 May 2019

Visualization of distinct substrate-recruitment pathways in the yeast exosome by EM.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48240

9 May 2019

Subunit architecture of multimeric complexes isolated directly from cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48240

9 May 2019

Crystal structure of an RNA-bound 11-subunit eukaryotic exosome complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48240

9 May 2019

A single subunit, Dis3, is essentially responsible for yeast exosome core activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48240

9 May 2019

A comprehensive two-hybrid analysis to explore the yeast protein interactome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48240

9 May 2019

Structure of an Rrp6–RNA exosome complex bound to poly(A) RNA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48240

9 May 2019

Probing genuine strong interactions and post-translational modifications in the heterogeneous yeast exosome protein complex.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48240

9 May 2019

RNA channelling by the eukaryotic exosome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48240

9 May 2019

Proteome survey reveals modularity of the yeast cell machinery

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48240

9 May 2019

RNA degradation paths in a 12-subunit nuclear exosome complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48240

9 May 2019

A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48240

9 May 2019

Architecture of the yeast Rrp44 exosome complex suggests routes of RNA recruitment for 3' end processing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48240

9 May 2019

The archaeal exosome core is a hexameric ring structure with three catalytic subunits

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48240

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48240

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48240

nuclear exosome (RNase complex)

IEA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48240

IDA

exosome (RNase complex)

1 reference

9 May 2019

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48240

cytoplasmic exosome (RNase complex)

IEA

nuclear exosome (RNase complex)

IDA

3 references

9 May 2019

The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48240

9 May 2019

Comparative multiplexed mass spectrometric analyses of endogenously expressed yeast nuclear and cytoplasmic exosomes.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48240

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48240

cytoplasmic exosome (RNase complex)

IBA

3 references

9 May 2019

The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48240

9 May 2019

Comparative multiplexed mass spectrometric analyses of endogenously expressed yeast nuclear and cytoplasmic exosomes.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48240

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48240

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48240

9 May 2019

Mutations in nucleolar proteins lead to nucleolar accumulation of polyA+ RNA in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48240

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48240

The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleases

IBA

biological process

nonfunctional rRNA decay

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48240

polyadenylation-dependent snoRNA 3'-end processing

IC

1 reference

5 June 2018

Yeast exosome mutants accumulate 3'-extended polyadenylated forms of U4 small nuclear RNA and small nucleolar RNAs

SGD

S000003390

http://www.ebi.ac.uk/QuickGO/annotations?protein=P48240&geneProductId=UniProtKB:P48240

nuclear polyadenylation-dependent tRNA catabolic process

3 references

9 May 2019

A new yeast poly(A) polymerase complex involved in RNA quality control

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48240

9 May 2019

RNA degradation by the exosome is promoted by a nuclear polyadenylation complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48240

9 May 2019

The exosome subunit Rrp44 plays a direct role in RNA substrate recognition

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48240

nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay

IDA

1 reference

9 May 2019

The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48240

U4 snRNA 3'-end processing

IC

1 reference

5 June 2018

Yeast exosome mutants accumulate 3'-extended polyadenylated forms of U4 small nuclear RNA and small nucleolar RNAs

SGD

S000003390

http://www.ebi.ac.uk/QuickGO/annotations?protein=P48240&geneProductId=UniProtKB:P48240

nuclear polyadenylation-dependent CUT catabolic process

1 reference

9 May 2019

A yeast exosome cofactor, Mpp6, functions in RNA surveillance and in the degradation of noncoding RNA transcripts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48240

nuclear mRNA surveillance

1 reference

5 June 2018

Identification of a regulated pathway for nuclear pre-mRNA turnover.

SGD

S000003390

http://www.ebi.ac.uk/QuickGO/annotations?protein=P48240&geneProductId=UniProtKB:P48240

nuclear polyadenylation-dependent mRNA catabolic process

1 reference

9 May 2019

The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48240

nuclear-transcribed mRNA catabolic process, non-stop decay

IC

1 reference

9 May 2019

The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48240

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48240

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

IEA

rRNA catabolic process

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48240

Exoribonuclease, phosphorolytic domain 1

IBA

has part(s)

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P48240

Identifiers

1 reference

20 March 2022

1 reference

25 May 2022

1 reference