ATP-dependent RNA helicase MTR4 YJL050W (Q27548544)

ATP-dependent RNA helicase Ski2-like

1 reference

P-loop containing nucleoside triphosphate hydrolase

1 reference

Helicase superfamily 1/2, ATP-binding domain, protein family

1 reference

Helicase, C-terminal domain, protein family

1 reference

DEAD/DEAH box helicase

1 reference

rRNA-processing arch domain, protein family

1 reference

ATP-dependent RNA helicase Ski2, C-terminal domain, protein family

1 reference

Saccharomyces cerevisiae S288c

found in taxon

1 reference

25 May 2022

1 reference

25 May 2022

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47047

1 reference

14 February 2019

poly(A) binding

1 reference

14 February 2019

Characterization of the essential activities of Saccharomyces cerevisiae Mtr4p, a 3'->5' helicase partner of the nuclear exosome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47047

helicase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47047

1 reference

14 February 2019

RNA binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47047

1 reference

14 February 2019

hydrolase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47047

1 reference

14 February 2019

nucleic acid binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47047

1 reference

14 February 2019

RNA helicase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47047

1 reference

14 February 2019

oxidoreductase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47047

1 reference

14 February 2019

3'-5' RNA helicase activity

Degradation of hypomodified tRNA(iMet) in vivo involves RNA-dependent ATPase activity of the DExH helicase Mtr4p

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47047

14 February 2019

Characterization of the essential activities of Saccharomyces cerevisiae Mtr4p, a 3'->5' helicase partner of the nuclear exosome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47047

14 February 2019

Degradation of hypomodified tRNA(iMet) in vivo involves RNA-dependent ATPase activity of the DExH helicase Mtr4p

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47047

nucleotide binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47047

1 reference

14 February 2019

protein binding

9 references

14 February 2019

RNA degradation by the exosome is promoted by a nuclear polyadenylation complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47047

14 February 2019

Proteomic analysis of interactors for yeast protein arginine methyltransferase Hmt1 reveals novel substrate and insights into additional biological roles

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47047

14 February 2019

Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47047

14 February 2019

The RNA helicase Mtr4p modulates polyadenylation in the TRAMP complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47047

14 February 2019

Structural analysis reveals the characteristic features of Mtr4, a DExH helicase involved in nuclear RNA processing and surveillance

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47047

14 February 2019

Proteome survey reveals modularity of the yeast cell machinery

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47047

14 February 2019

Cryptic pol II transcripts are degraded by a nuclear quality control pathway involving a new poly(A) polymerase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47047

14 February 2019

Yeast Trf5p is a nuclear poly(A) polymerase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47047

14 February 2019

A new yeast poly(A) polymerase complex involved in RNA quality control

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47047

mRNA binding

HDA

1 reference

14 February 2019

Global analysis of yeast mRNPs

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47047

HDA

cell component

nucleolus

1 reference

14 February 2019

Surveillance of nuclear-restricted pre-ribosomes within a subnucleolar region of Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47047

TRAMP complex

Cryptic pol II transcripts are degraded by a nuclear quality control pathway involving a new poly(A) polymerase

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47047

14 February 2019

Cryptic pol II transcripts are degraded by a nuclear quality control pathway involving a new poly(A) polymerase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47047

14 February 2019

RNA degradation by the exosome is promoted by a nuclear polyadenylation complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47047

14 February 2019

A new yeast poly(A) polymerase complex involved in RNA quality control

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47047

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?protein=P47047&geneProductId=UniProtKB:P47047

3 references

27 March 2018

27 March 2018

Diazaborine treatment of yeast cells inhibits maturation of the 60S ribosomal subunit

http://www.ebi.ac.uk/QuickGO/annotations?protein=P47047&geneProductId=UniProtKB:P47047

27 March 2018

A DEAD-box-family protein is required for nucleocytoplasmic transport of yeast mRNA

http://www.ebi.ac.uk/QuickGO/annotations?protein=P47047&geneProductId=UniProtKB:P47047

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47047

4 references

14 February 2019

14 February 2019

Diazaborine treatment of yeast cells inhibits maturation of the 60S ribosomal subunit

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47047

14 February 2019

A DEAD-box-family protein is required for nucleocytoplasmic transport of yeast mRNA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47047

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47047

nuclear polyadenylation-dependent rRNA catabolic process

IBA

biological process

polyadenylation-dependent snoRNA 3'-end processing

1 reference

14 February 2019

Yeast exosome mutants accumulate 3'-extended polyadenylated forms of U4 small nuclear RNA and small nucleolar RNAs

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47047

nuclear polyadenylation-dependent tRNA catabolic process

Degradation of hypomodified tRNA(iMet) in vivo involves RNA-dependent ATPase activity of the DExH helicase Mtr4p

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47047

IGI

14 February 2019

The exosome subunit Rrp44 plays a direct role in RNA substrate recognition

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47047

14 February 2019

RNA degradation by the exosome is promoted by a nuclear polyadenylation complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47047

14 February 2019

A new yeast poly(A) polymerase complex involved in RNA quality control

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47047

RNA catabolic process

http://www.ebi.ac.uk/QuickGO/annotations?protein=P47047&geneProductId=UniProtKB:P47047

1 reference

27 March 2018

exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

rRNA catabolic process

U4 snRNA 3'-end processing

nuclear polyadenylation-dependent mRNA catabolic process

1 reference

14 February 2019

Regulation of NAB2 mRNA 3'-end formation requires the core exosome and the Trf4p component of the TRAMP complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47047

U5 snRNA 3'-end processing

1 reference

14 February 2019

Functions of the exosome in rRNA, snoRNA and snRNA synthesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47047

ncRNA polyadenylation

nuclear mRNA surveillance of mRNA 3'-end processing

IGI

rRNA processing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47047

1 reference

14 February 2019

poly(A)+ mRNA export from nucleus

1 reference

14 February 2019

Altered RNA processing and export lead to retention of mRNAs near transcription sites and nuclear pore complexes or within the nucleolus.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47047

maturation of 5.8S rRNA

IBA

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47047

DEAD/DEAH box helicase domain

IBA

has part(s)

1 reference

ATP-dependent RNA helicase Ski2, C-terminal

1 reference

rRNA-processing arch domain

1 reference

Helicase superfamily 1/2, ATP-binding domain

1 reference

Helicase, C-terminal

1 reference

Identifiers

1 reference

20 March 2022

1 reference

25 May 2022

1 reference