Isoform-specific potentiation of stem and progenitor cell engraftment by AML1/RUNX1 (Q27307661)

4

object named as

Keitaro Matsuo

0 references

Masao Seto

5

object named as

Masao Seto

0 references

Shinobu Tsuzuki

1

object named as

Shinobu Tsuzuki

0 references

author name string

Dengli Hong

2

0 references

Rajeev Gupta

Creative Commons Attribution 4.0 International

3

0 references

language of work or name

English

0 references

publication date

May 2007

0 references

published in

PLOS MEDICINE

0 references

volume

4

0 references

issue

5

0 references

page(s)

e172

0 references

copyright license

start time

15 May 2007

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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21 March 2017

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21 March 2017

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Loss of Runx1 perturbs adult hematopoiesis and is associated with a myeloproliferative phenotype.

28 September 2017

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Clinical strategies for expansion of haematopoietic stem cells

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GATA-2 plays two functionally distinct roles during the ontogeny of hematopoietic stem cells

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Modeling first-hit functions of the t(12;21) TEL-AML1 translocation in mice

28 September 2017

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Functional analysis of a dominant-negative DeltaETS TEL/ETV6 isoform

28 September 2017

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AML-1 is required for megakaryocytic maturation and lymphocytic differentiation, but not for maintenance of hematopoietic stem cells in adult hematopoiesis

28 September 2017

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VWRPY motif–dependent and –independent roles of AML1/Runx1 transcription factor in murine hematopoietic development

28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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Forced expression of the Ikaros 6 isoform in human placental blood CD34(+) cells impairs their ability to differentiate toward the B-lymphoid lineage

28 September 2017

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Leukemogenesis by CBF oncoproteins

28 September 2017

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Biological characteristics of the leukemia-associated transcriptional factor AML1 disclosed by hematopoietic rescue of AML1-deficient embryonic stem cells by using a knock-in strategy

28 September 2017

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Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia

28 September 2017

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Enforced expression of the GATA-2 transcription factor blocks normal hematopoiesis.

28 September 2017

1 reference

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Culture system for extensive production of CD19+IgM+ cells by human cord blood CD34+ progenitors

28 September 2017

1 reference

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A combination of stem cell factor and granulocyte colony-stimulating factor enhances the growth of human progenitor B cells supported by murine stromal cell line MS-5.

28 September 2017

1 reference

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Kinetic evidence of the regeneration of multilineage hematopoiesis from primitive cells in normal human bone marrow transplanted into immunodeficient mice

28 September 2017

1 reference

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PEBP2 alpha B/mouse AML1 consists of multiple isoforms that possess differential transactivation potentials

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868041

An acute myeloid leukemia gene, AML1, regulates hemopoietic myeloid cell differentiation and transcriptional activation antagonistically by two alternative spliced forms.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868041

t(8;21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene, AML1

28 September 2017

1 reference

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Hematopoietic stem cells express multiple myeloid markers: implications for the origin and targeted therapy of acute myeloid leukemia

28 September 2017

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Cbfa2 is required for the formation of intra-aortic hematopoietic clusters.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868041

Reproducible establishment of hemopoietic supportive stromal cell lines from murine bone marrow

31 May 2018

1 reference

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Genetic regulatory networks programming hematopoietic stem cells and erythroid lineage specification.

31 May 2018

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28 November 2018

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Mutations of AML1 are common in therapy-related myelodysplasia following therapy with alkylating agents and are significantly associated with deletion or loss of chromosome arm 7q and with subsequent leukemic transformation

28 November 2018

1 reference

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High incidence of somatic mutations in the AML1/RUNX1 gene in myelodysplastic syndrome and low blast percentage myeloid leukemia with myelodysplasia

28 November 2018

1 reference

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Maintaining the self-renewal and differentiation potential of human CD34+ hematopoietic cells using a single genetic element.

28 November 2018

1 reference

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Frequent mutations in the GATA-1 gene in the transient myeloproliferative disorder of Down syndrome

28 November 2018

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High-level transduction and gene expression in hematopoietic repopulating cells using a human immunodeficiency [correction of imunodeficiency] virus type 1-based lentiviral vector containing an internal spleen focus forming virus promoter

28 November 2018

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Identification of an alternatively spliced form of the mouse AML1/RUNX1 gene transcript AML1c and its expression in early hematopoietic development.

28 November 2018

1 reference

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Rapid development of a quantitative-competitive (qc) RT-PCR assay using a composite primer approach

28 November 2018

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12 December 2020

CD34+AC133+ Cells Isolated from Cord Blood are Highly Enriched in Long‐Term Culture‐Initiating Cells, NOD/SCID‐Repopulating Cells and Dendritic Cell Progenitors

1 reference

12 December 2020

Engraftment in nonobese diabetic severe combined immunodeficient mice of human CD34(+) cord blood cells after ex vivo expansion: evidence for the amplification and self-renewal of repopulating stem cells

1 reference

12 December 2020

Purification, amplification and characterization of a population of human erythroid progenitors

1 reference

12 December 2020

Transduction of Human CD34+CD38- Bone Marrow and Cord Blood-Derived SCID-Repopulating Cells with Third-Generation Lentiviral Vectors

1 reference

12 December 2020

Dominant negative isoform of the Ikaros gene in patients with adult B-cell acute lymphoblastic leukemia

1 reference

12 December 2020

Immunophenotypic and functional characterization of CD33(+)CD34(+) cells in human cord blood of preterm neonates

1 reference

12 December 2020

Mutations of the AML1 gene in myelodysplastic syndrome and their functional implications in leukemogenesis

1 reference

12 December 2020

Haploinsufficiency of AML1 affects the temporal and spatial generation of hematopoietic stem cells in the mouse embryo

1 reference

12 December 2020

Haploinsufficiency of AML1 results in a decrease in the number of LTR-HSCs while simultaneously inducing an increase in more mature progenitors

1 reference

12 December 2020

10.1371/JOURNAL.PMED.0040172

Identifiers

DOI

1 reference

1 reference

1 reference

PubMed publication ID

17503961

1 reference