Deciphering the complexities of atopic dermatitis: shifting paradigms in treatment approaches (Q26852335)

language of work or name

1 reference

October 2014

1 reference

The Journal of Allergy and Clinical Immunology

published in

1 reference

volume

134

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issue

4

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page(s)

769-79

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Defects of filaggrin-like proteins in both lesional and nonlesional atopic skin

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Hornerin is a component of the epidermal cornified cell envelopes

7 April 2017

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The ABC's of managing patients with severe atopic dermatitis

7 April 2017

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Temporal shifts in the skin microbiome associated with disease flares and treatment in children with atopic dermatitis

7 April 2017

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The burden of disease associated with filaggrin mutations: a population-based, longitudinal birth cohort study

7 April 2017

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IL-22 increases the innate immunity of tissues

7 April 2017

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Interleukin 31, a cytokine produced by activated T cells, induces dermatitis in mice

7 April 2017

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Tmem79/Matt is the matted mouse gene and is a predisposing gene for atopic dermatitis in human subjects

7 April 2017

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A homozygous nonsense mutation in the gene for Tmem79, a component for the lamellar granule secretory system, produces spontaneous eczema in an experimental model of atopic dermatitis

7 April 2017

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Interleukin-22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis

7 April 2017

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Atopic dermatitis increases the effect of exposure to peanut antigen in dust on peanut sensitization and likely peanut allergy

7 April 2017

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Peanut allergy: effect of environmental peanut exposure in children with filaggrin loss-of-function mutations

28 September 2017

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Randomized trial of vitamin D supplementation for winter-related atopic dermatitis in children

28 September 2017

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Peeling off the genetics of atopic dermatitis-like congenital disorders

28 September 2017

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The Harmonising Outcome Measures for Eczema (HOME) statement to assess clinical signs of atopic eczema in trials

28 September 2017

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Identification of novel gene signatures in patients with atopic dermatitis complicated by eczema herpeticum

28 September 2017

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Causes of epidermal filaggrin reduction and their role in the pathogenesis of atopic dermatitis

28 September 2017

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Atopic dermatitis in children

28 September 2017

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Skin barrier and immune dysregulation in atopic dermatitis: an evolving story with important clinical implications

28 September 2017

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Residual genomic profile after cyclosporine treatment may offer insights into atopic dermatitis reoccurrence

28 September 2017

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Filaggrin-stratified transcriptomic analysis of pediatric skin identifies mechanistic pathways in patients with atopic dermatitis

28 September 2017

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Cyclosporine in patients with atopic dermatitis modulates activated inflammatory pathways and reverses epidermal pathology.

28 September 2017

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Plasmacytoid dendritic cell depletion in DOCK8 deficiency: rescue of severe herpetic infections with IFN-α 2b therapy

28 September 2017

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An integrated epigenetic and transcriptomic analysis reveals distinct tissue-specific patterns of DNA methylation associated with atopic dermatitis

28 September 2017

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Are the concepts of induction of remission and treatment of subclinical inflammation in atopic dermatitis clinically useful?

28 September 2017

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Anti-inflammatory and corticosteroid-enhancing actions of vitamin D in monocytes of patients with steroid-resistant and those with steroid-sensitive asthma

28 September 2017

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Low vitamin D levels are associated with atopic dermatitis, but not allergic rhinitis, asthma, or IgE sensitization, in the adult Korean population

28 September 2017

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Guidelines of care for the management of atopic dermatitis: section 1. Diagnosis and assessment of atopic dermatitis

28 September 2017

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Efficacy and safety of systemic treatments for moderate-to-severe atopic dermatitis: a systematic review

28 September 2017

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Filaggrin-2 variation is associated with more persistent atopic dermatitis in African American subjects

28 September 2017

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Childhood atopic dermatitis and warts are associated with increased risk of infection: a US population-based study

28 September 2017

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Possible new therapeutic strategy to regulate atopic dermatitis through upregulating filaggrin expression

28 September 2017

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Assessment of clinical signs of atopic dermatitis: a systematic review and recommendation

28 September 2017

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Racial comparison of filaggrin null mutations in asthmatic patients with atopic dermatitis in a US population

28 September 2017

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Intrinsic atopic dermatitis shows similar TH2 and higher TH17 immune activation compared with extrinsic atopic dermatitis.

28 September 2017

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Attenuated neutrophil axis in atopic dermatitis compared to psoriasis reflects TH17 pathway differences between these diseases

28 September 2017

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Fungal protein MGL_1304 in sweat is an allergen for atopic dermatitis patients

28 September 2017

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IL-25 enhances HSV-1 replication by inhibiting filaggrin expression, and acts synergistically with Th2 cytokines to enhance HSV-1 replication.

28 September 2017

1 reference

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Efficacy of allergen-specific immunotherapy for atopic dermatitis: a systematic review and meta-analysis of randomized controlled trials.

28 September 2017

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Endotypes and phenotypes of chronic rhinosinusitis: a PRACTALL document of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma & Immunology

28 September 2017

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Characterization of different courses of atopic dermatitis in adolescent and adult patients

28 September 2017

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Vitamin D in allergic disease: shedding light on a complex problem

28 September 2017

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Atopic dermatitis: a practice parameter update 2012.

28 September 2017

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The multifunctional role of filaggrin in allergic skin disease

28 September 2017

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The cutaneous innate immune response in patients with atopic dermatitis.

28 September 2017

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Clinical phenotypes of chronic obstructive pulmonary disease and asthma: recent advances

28 September 2017

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Filaggrin-dependent secretion of sphingomyelinase protects against staphylococcal α-toxin-induced keratinocyte death

28 September 2017

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Mental health comorbidity in patients with atopic dermatitis

28 September 2017

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Atopic dermatitis 2.0: from the clinical phenotype to the molecular taxonomy and stratified medicine

28 September 2017

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The persistence of atopic dermatitis and filaggrin (FLG) mutations in a US longitudinal cohort

28 September 2017

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IL-13 in asthma and allergic disease: asthma phenotypes and targeted therapies

28 September 2017

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Progressive activation of T(H)2/T(H)22 cytokines and selective epidermal proteins characterizes acute and chronic atopic dermatitis

28 September 2017

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Thymic stromal lymphopoietin and allergic disease

28 September 2017

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Atopic dermatitis results in intrinsic barrier and immune abnormalities: implications for contact dermatitis

28 September 2017

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Comparative transcriptomic analyses of atopic dermatitis and psoriasis reveal shared neutrophilic inflammation.

28 September 2017

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Staphylococcus aureus α-toxin modulates skin host response to viral infection

28 September 2017

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Mechanisms of IFN-γ-induced apoptosis of human skin keratinocytes in patients with atopic dermatitis

28 September 2017

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How should an incident case of atopic dermatitis be defined? A systematic review of primary prevention studies

28 September 2017

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Does "autoreactivity" play a role in atopic dermatitis?

28 September 2017

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Langerhans cells are critical in epicutaneous sensitization with protein antigen via thymic stromal lymphopoietin receptor signaling.

28 September 2017

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An update on the role of human dendritic cells in patients with atopic dermatitis

28 September 2017

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Filaggrin loss-of-function mutations are associated with enhanced expression of IL-1 cytokines in the stratum corneum of patients with atopic dermatitis and in a murine model of filaggrin deficiency.

28 September 2017

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IL-31 regulates differentiation and filaggrin expression in human organotypic skin models

28 September 2017

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Intragenic copy number variation within filaggrin contributes to the risk of atopic dermatitis with a dose-dependent effect

28 September 2017

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Filaggrin mutations associated with skin and allergic diseases.

28 September 2017

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Reversal of atopic dermatitis with narrow-band UVB phototherapy and biomarkers for therapeutic response

28 September 2017

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Atopic dermatitis: a disease of altered skin barrier and immune dysregulation

28 September 2017

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Human atopic dermatitis complicated by eczema herpeticum is associated with abnormalities in IFN-γ response

28 September 2017

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Nonlesional atopic dermatitis skin is characterized by broad terminal differentiation defects and variable immune abnormalities

28 September 2017

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Comparative proteomic profiling of patients with atopic dermatitis based on history of eczema herpeticum infection and Staphylococcus aureus colonization

28 September 2017

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Efficacy and tolerability of proactive treatment with topical corticosteroids and calcineurin inhibitors for atopic eczema: systematic review and meta-analysis of randomized controlled trials

28 September 2017

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Eczema prevalence in the United States: data from the 2003 National Survey of Children's Health

28 September 2017

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Activation of TLR2 by a small molecule produced by Staphylococcus epidermidis increases antimicrobial defense against bacterial skin infections

28 September 2017

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Inflammation-associated S100 proteins: new mechanisms that regulate function.

28 September 2017

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IL-4 regulates skin homeostasis and the predisposition toward allergic skin inflammation

28 September 2017

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Secreted virulence factor comparison between methicillin-resistant and methicillin-sensitive Staphylococcus aureus, and its relevance to atopic dermatitis

28 September 2017

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An update on the genetics of atopic dermatitis: scratching the surface in 2009.

28 September 2017

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Filaggrin-deficient mice exhibit TH17-dominated skin inflammation and permissiveness to epicutaneous sensitization with protein antigen

28 September 2017

1 reference

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Phenotype of atopic dermatitis subjects with a history of eczema herpeticum.

28 September 2017

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Th17 cytokines interleukin (IL)-17 and IL-22 modulate distinct inflammatory and keratinocyte-response pathways.

28 September 2017

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Th2 cytokines act on S100/A11 to downregulate keratinocyte differentiation

28 September 2017

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Loricrin and involucrin expression is down-regulated by Th2 cytokines through STAT-6

28 September 2017

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Cytokine modulation of atopic dermatitis filaggrin skin expression

28 September 2017

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Cathelicidin deficiency predisposes to eczema herpeticum

28 September 2017

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IL-22 inhibits epidermal differentiation and induces proinflammatory gene expression and migration of human keratinocytes

28 September 2017

1 reference

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Endogenous antimicrobial peptides and skin infections in atopic dermatitis

28 September 2017

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Differential in situ cytokine gene expression in acute versus chronic atopic dermatitis

28 September 2017

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South African amaXhosa patients with atopic dermatitis have decreased levels of filaggrin breakdown products but no loss-of-function mutations in filaggrin

28 September 2017

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TH2 cytokines increase kallikrein 7 expression and function in patients with atopic dermatitis.

31 May 2018

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Wet wrap therapy in children with moderate to severe atopic dermatitis in a multidisciplinary treatment program.

31 May 2018

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MicroRNA-146a alleviates chronic skin inflammation in atopic dermatitis through suppression of innate immune responses in keratinocytes.

28 November 2018

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Increased compound heterozygous filaggrin mutations in severe atopic dermatitis in the United States

28 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186710

Epicutaneous application of house dust mite induces thymic stromal lymphopoietin in nonlesional skin of patients with atopic dermatitis.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186710

Systemic therapies for severe atopic dermatitis in children and adults.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186710

28 November 2018

Reply: To PMID 23453797.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186710

Vitamin D and food allergy in patients with severe atopic dermatitis

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186710

Establishment of the intestinal microbiota and its role for atopic dermatitis in early childhood

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186710

Symptoms of atopic dermatitis are influenced by outdoor air pollution.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186710

Enhanced production of IL-17A in patients with severe asthma is inhibited by 1α,25-dihydroxyvitamin D3 in a glucocorticoid-independent fashion.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186710

Residual genomic signature of atopic dermatitis despite clinical resolution with narrow-band UVB.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186710

Efficacy and safety of subcutaneous allergen-specific immunotherapy with depigmented polymerized mite extract in atopic dermatitis.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186710

Development of atopic dermatitis according to age of onset and association with early-life exposures

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186710

Oral application of bacterial lysate in infancy decreases the risk of atopic dermatitis in children with 1 atopic parent in a randomized, placebo-controlled trial.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186710

Filaggrin mutations increase the risk for persistent dry skin and eczema independent of sensitization.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186710

Association screening in the Epidermal Differentiation Complex (EDC) identifies an SPRR3 repeat number variant as a risk factor for eczema.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186710

Different effects of pimecrolimus and betamethasone on the skin barrier in patients with atopic dermatitis

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186710

Filaggrin variants confer susceptibility to asthma

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186710

Expression of interleukin-4 in the epidermis of transgenic mice results in a pruritic inflammatory skin disease: an experimental animal model to study atopic dermatitis.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186710

IL-13/IL-22-coproducing T cells, a novel subset, are increased in atopic dermatitis

28 November 2018

1 reference

12 December 2020

Fibronectin and fibrinogen contribute to the enhanced binding of Staphylococcus aureus to atopic skin

1 reference

12 December 2020

1 reference

12 December 2020

Allergic hyperreactivity to microbial components: a trigger factor of "intrinsic" atopic dermatitis?

1 reference

12 December 2020

Characterization of the mononuclear cell infiltrate in atopic dermatitis using monoclonal antibodies

1 reference

12 December 2020

The suppressive role of IL-10 in contact and atopic dermatitis

1 reference

12 December 2020

Preferential binding of Staphylococcus aureus to skin sites of Th2-mediated inflammation in a murine model

1 reference

12 December 2020

Dupilumab treatment in adults with moderate-to-severe atopic dermatitis

1 reference

12 December 2020

Early probiotic supplementation for allergy prevention: long-term outcomes

1 reference

12 December 2020

S100A8/A9, a key mediator for positive feedback growth stimulation of normal human keratinocytes

1 reference

12 December 2020

Proteome analysis of stratum corneum from atopic dermatitis patients by hybrid quadrupole-orbitrap mass spectrometer

1 reference

12 December 2020

Broad defects in epidermal cornification in atopic dermatitis identified through genomic analysis

1 reference

12 December 2020

Altered stratum corneum barrier and enhanced percutaneous immune responses in filaggrin-null mice

1 reference

12 December 2020

IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes: a potential role in psoriasis

1 reference

12 December 2020

Recent insights into atopic dermatitis and implications for management of infectious complications

1 reference

https://api.crossref.org/works/10.1016%2FJ.JACI.2014.08.008

7 January 2021

Mechanisms of abnormal lamellar body secretion and the dysfunctional skin barrier in patients with atopic dermatitis

1 reference

https://api.crossref.org/works/10.1016%2FJ.JACI.2014.08.008

7 January 2021

Filaggrin loss-of-function mutations are associated with food allergy in childhood and adolescence

1 reference

https://api.crossref.org/works/10.1016%2FJ.JACI.2014.08.008

7 January 2021

Application of moisturizer to neonates prevents development of atopic dermatitis

1 reference

https://api.crossref.org/works/10.1016%2FJ.JACI.2014.08.008

7 January 2021

Emollient enhancement of the skin barrier from birth offers effective atopic dermatitis prevention

1 reference

https://api.crossref.org/works/10.1016%2FJ.JACI.2014.08.008

7 January 2021

10.1016/J.JACI.2014.08.008

Identifiers

DOI

1 reference

567050

567050

1 reference

1 reference

1 reference