Fueling the flames: Mammalian programmed necrosis in inflammatory diseases (Q26830515)

Crossref

language of work or name

1 reference

1 November 2012

1 reference

Cold Spring Harbor Perspectives in Biology

published in

1 reference

Crossref

volume

4

1 reference

issue

11

1 reference

The RIP1/RIP3 necrosome forms a functional amyloid signaling complex required for programmed necrosis

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Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase

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cIAPs block Ripoptosome formation, a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms

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NEMO and RIP1 control cell fate in response to extensive DNA damage via TNF-α feedforward signaling

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Riboflavin kinase couples TNF receptor 1 to NADPH oxidase

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DAI/ZBP1 recruits RIP1 and RIP3 through RIP homotypic interaction motifs to activate NF-kappaB

7 April 2017

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Mitochondrial phosphoglycerate mutase 5 uses alternate catalytic activity as a protein serine/threonine phosphatase to activate ASK1

7 April 2017

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Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation

7 April 2017

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Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha

7 April 2017

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TNF-alpha induces two distinct caspase-8 activation pathways

7 April 2017

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IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis

7 April 2017

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IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis

7 April 2017

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Autocrine TNFalpha signaling renders human cancer cells susceptible to Smac-mimetic-induced apoptosis

7 April 2017

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Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes

7 April 2017

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Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis

7 April 2017

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TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex

7 April 2017

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Apoptosis, oncosis, and necrosis. An overview of cell death

7 April 2017

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RIP: a novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death

7 April 2017

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An endotoxin-induced serum factor that causes necrosis of tumors

7 April 2017

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Viral infection and the evolution of caspase 8-regulated apoptotic and necrotic death pathways

7 April 2017

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Ubiquitin chain editing revealed by polyubiquitin linkage-specific antibodies

7 April 2017

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cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination

7 April 2017

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PGAM5 tethers a ternary complex containing Keap1 and Nrf2 to mitochondria

7 April 2017

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Regulation of NF-kappaB activity and keratinocyte differentiation by the RIP4 protein: implications for cutaneous wound repair

7 April 2017

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Complementary roles of Fas-associated death domain (FADD) and receptor interacting protein kinase-3 (RIPK3) in T-cell homeostasis and antiviral immunity

7 April 2017

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RIP1-dependent and independent effects of necrostatin-1 in necrosis and T cell activation

7 April 2017

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Survival function of the FADD-CASPASE-8-cFLIP(L) complex

7 April 2017

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Caspase 8 inhibits programmed necrosis by processing CYLD

7 April 2017

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Mechanisms of necroptosis in T cells

7 April 2017

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Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis

7 April 2017

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cIAP1 and TAK1 protect cells from TNF-induced necrosis by preventing RIP1/RIP3-dependent reactive oxygen species production

7 April 2017

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RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis

7 April 2017

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Receptor-interacting protein homotypic interaction motif-dependent control of NF-kappa B activation via the DNA-dependent activator of IFN regulatory factors

7 April 2017

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Ubiquitination of RIP1 regulates an NF-kappaB-independent cell-death switch in TNF signaling

7 April 2017

1 reference

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Target protease specificity of the viral serpin CrmA. Analysis of five caspases

7 April 2017

1 reference

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RIP3 mediates the embryonic lethality of caspase-8-deficient mice

7 April 2017

1 reference

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Molecular mechanisms of necroptosis: an ordered cellular explosion

7 April 2017

1 reference

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Identification of RIP1 kinase as a specific cellular target of necrostatins

7 April 2017

1 reference

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Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO

7 April 2017

1 reference

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Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury

7 April 2017

1 reference

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Regulation of an ATG7-beclin 1 program of autophagic cell death by caspase-8

7 April 2017

1 reference

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The death domain kinase RIP mediates the TNF-induced NF-kappaB signal

7 April 2017

1 reference

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cIAP1 and cIAP2 limit macrophage necroptosis by inhibiting Rip1 and Rip3 activation.

7 April 2017

1 reference

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Mixed lineage kinase domain-like is a key receptor interacting protein 3 downstream component of TNF-induced necrosis

28 September 2017

1 reference

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Rip1 (receptor-interacting protein kinase 1) mediates necroptosis and contributes to renal ischemia/reperfusion injury

28 September 2017

1 reference

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Toll-like receptors activate programmed necrosis in macrophages through a receptor-interacting kinase-3-mediated pathway

28 September 2017

1 reference

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Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis.

28 September 2017

1 reference

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The Ripoptosome, a signaling platform that assembles in response to genotoxic stress and loss of IAPs

28 September 2017

1 reference

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Functional complementation between FADD and RIP1 in embryos and lymphocytes

28 September 2017

1 reference

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Receptor interacting protein kinases mediate retinal detachment-induced photoreceptor necrosis and compensate for inhibition of apoptosis

28 September 2017

1 reference

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Necrostatin decreases oxidative damage, inflammation, and injury after neonatal HI.

28 September 2017

1 reference

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Virus inhibition of RIP3-dependent necrosis

28 September 2017

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Cellular IAPs inhibit a cryptic CD95-induced cell death by limiting RIP1 kinase recruitment

28 September 2017

1 reference

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Necroptosis, necrosis and secondary necrosis converge on similar cellular disintegration features.

28 September 2017

1 reference

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A ubiquitin replacement strategy in human cells reveals distinct mechanisms of IKK activation by TNFalpha and IL-1beta.

28 September 2017

1 reference

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Membrane-bound Fas ligand requires RIP1 for efficient activation of caspase-8 within the death-inducing signaling complex

28 September 2017

1 reference

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The p53-cathepsin axis cooperates with ROS to activate programmed necrotic death upon DNA damage

28 September 2017

1 reference

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Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway

28 September 2017

1 reference

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Antigen-mediated T cell expansion regulated by parallel pathways of death

28 September 2017

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Cytomegalovirus M45 cell death suppression requires receptor-interacting protein (RIP) homotypic interaction motif (RHIM)-dependent interaction with RIP1.

28 September 2017

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Genetic defects of apoptosis and primary immunodeficiency

28 September 2017

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The cardioprotective effect of necrostatin requires the cyclophilin-D component of the mitochondrial permeability transition pore

28 September 2017

1 reference

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Necrostatin: a potentially novel cardioprotective agent?

28 September 2017

1 reference

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Cleavage of RIP3 inactivates its caspase-independent apoptosis pathway by removal of kinase domain.

28 September 2017

1 reference

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TNF-induced activation of the Nox1 NADPH oxidase and its role in the induction of necrotic cell death

28 September 2017

1 reference

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PIDD mediates NF-kappaB activation in response to DNA damage

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536335

RIP links TLR4 to Akt and is essential for cell survival in response to LPS stimulation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536335

RIP1 is an essential mediator of Toll-like receptor 3-induced NF-kappa B activation

28 September 2017

1 reference

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The ribonucleotide reductase R1 homolog of murine cytomegalovirus is not a functional enzyme subunit but is required for pathogenesis

28 September 2017

1 reference

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Kinase RIP3 is dispensable for normal NF-kappa Bs, signaling by the B-cell and T-cell receptors, tumor necrosis factor receptor 1, and Toll-like receptors 2 and 4.

28 September 2017

1 reference

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The death domain kinase RIP has an essential role in DNA damage-induced NF-kappa B activation

28 September 2017

1 reference

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A ribonucleotide reductase homolog of cytomegalovirus and endothelial cell tropism.

28 September 2017

1 reference

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Induction of necrotic-like cell death by tumor necrosis factor alpha and caspase inhibitors: novel mechanism for killing virus-infected cells

28 September 2017

1 reference

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Redox regulation of TNF signaling

28 September 2017

1 reference

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Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors

28 September 2017

1 reference

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Death effector domain-containing herpesvirus and poxvirus proteins inhibit both Fas- and TNFR1-induced apoptosis

28 September 2017

1 reference

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RIP mediates tumor necrosis factor receptor 1 activation of NF-kappaB but not Fas/APO-1-initiated apoptosis

28 September 2017

1 reference

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DAI/ZBP1/DLM-1 complexes with RIP3 to mediate virus-induced programmed necrosis that is targeted by murine cytomegalovirus vIRA.

28 September 2017

1 reference

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A cytosolic ATM/NEMO/RIP1 complex recruits TAK1 to mediate the NF-kappaB and p38 mitogen-activated protein kinase (MAPK)/MAPK-activated protein 2 responses to DNA damage

31 May 2018

1 reference

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Caspase-8 deficiency in epidermal keratinocytes triggers an inflammatory skin disease

31 May 2018

1 reference

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Growth arrest and autophagy are required for salivary gland cell degradation in Drosophila

31 May 2018

1 reference

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Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor.

31 May 2018

1 reference

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Inhibitor of apoptosis proteins limit RIP3 kinase-dependent interleukin-1 activation.

31 May 2018

1 reference

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FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation.

28 November 2018

1 reference

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RIPK1 is not essential for TNFR1-induced activation of NF-kappaB.

28 November 2018

1 reference

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Ubiquitination of RIP Is Required for Tumor Necrosis Factor α-induced NF-κB Activation

28 November 2018

1 reference

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A role for tumor necrosis factor receptor-2 and receptor-interacting protein in programmed necrosis and antiviral responses

28 November 2018

1 reference

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A novel family of viral death effector domain-containing molecules that inhibit both CD-95- and tumor necrosis factor receptor-1-induced apoptosis

28 November 2018

1 reference

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inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The Adaptor Protein FADD Protects Epidermal Keratinocytes from Necroptosis In Vivo and Prevents Skin Inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/23125016

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1101/CSHPERSPECT.A008805

1 reference

release_wheirhf6ljak5ipfsx2lvtqb3a

1688411

Fatcat ID

0 references

1688411

1 reference

1 reference

1 reference