Disruption of ion homeostasis in the neurogliovascular unit underlies the pathogenesis of ischemic cerebral edema (Q26825616)

Kristopher T. Kahle

2

1 reference

Brian P. Walcott

3

1 reference

Volodymyr Gerzanich

4

1 reference

J. Marc Simard

5

1 reference

language of work or name

1 reference

February 2014

1 reference

Translational stroke research

published in

1 reference

volume

5

1 reference

issue

1

1 reference

page(s)

3-16

1 reference

https://scigraph.springernature.com/pub.10.1007/s12975-013-0307-9

exact match

0 references

cites work

Drugs acting on SUR1 to treat CNS ischemia and trauma

1 reference

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Sulfonylureas improve outcome in patients with type 2 diabetes and acute ischemic stroke

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Newly expressed SUR1-regulated NC(Ca-ATP) channel mediates cerebral edema after ischemic stroke

7 April 2017

1 reference

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The tarantula toxin psalmotoxin 1 inhibits acid-sensing ion channel (ASIC) 1a by increasing its apparent H+ affinity

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Four Na+/H+ exchanger isoforms are distributed to Golgi and post-Golgi compartments and are involved in organelle pH regulation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Human Neuroepithelial Cells Express NMDA Receptors

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Regulation of melastatin, a TRP-related protein, through interaction with a cytoplasmic isoform

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Identification of arylsulfonamides as Aquaporin 4 inhibitors

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Astrocyte-endothelial interactions at the blood-brain barrier

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Molecular mechanisms of glutamate receptor-mediated excitotoxic neuronal cell death

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

LTRPC2 Ca2+-permeable channel activated by changes in redox status confers susceptibility to cell death

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Nonsteroid anti-inflammatory drugs inhibit both the activity and the inflammation-induced expression of acid-sensing ion channels in nociceptors

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

ATP-dependent potassium channel blockade strengthens microglial neuroprotection after hypoxia-ischemia in rats

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

The Ste20 kinases Ste20-related proline-alanine-rich kinase and oxidative-stress response 1 regulate NKCC1 function in sensory neurons

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Subunit-dependent high-affinity zinc inhibition of acid-sensing ion channels

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

TRPM4 is a Ca2+-activated nonselective cation channel mediating cell membrane depolarization

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Functional characterization of the neuronal-specific K-Cl cotransporter: implications for [K+]o regulation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Glibenclamide reduces inflammation, vasogenic edema, and caspase-3 activation after subarachnoid hemorrhage

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Structure and function of the blood-brain barrier

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Limitations of Current GABA Agonists in Neonatal Seizures: Toward GABA Modulation Via the Targeting of Neuronal Cl(-) Transport

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

The sulfonylurea receptor 1 (Sur1)-transient receptor potential melastatin 4 (Trpm4) channel

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Intravenous HOE-642 reduces brain edema and Na uptake in the rat permanent middle cerebral artery occlusion model of stroke: evidence for participation of the blood-brain barrier Na/H exchanger

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Tight junctions at the blood brain barrier: physiological architecture and disease-associated dysregulation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Does inhibiting Sur1 complement rt-PA in cerebral ischemia?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Glibenclamide Administration Attenuates Infarct Volume, Hemispheric Swelling, and Functional Impairments following Permanent Focal Cerebral Ischemia in Rats

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Glibenclamide-10-h Treatment Window in a Clinically Relevant Model of Stroke

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Tight junction in blood-brain barrier: an overview of structure, regulation, and regulator substances

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Neurovascular unit: a focus on pericytes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Integrins as receptor targets for neurological disorders

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Sensitive isotope dilution liquid chromatography/tandem mass spectrometry method for quantitative analysis of bumetanide in serum and brain tissue

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Inhibiting the Na+/H+ exchanger reduces reperfusion injury: a small animal MRI study

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

The pattern of leptomeningeal collaterals on CT angiography is a strong predictor of long-term functional outcome in stroke patients with large vessel intracranial occlusion

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Phosphoregulation of the Na-K-2Cl and K-Cl cotransporters by the WNK kinases

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Possible involvement of DNA methylation in NKCC1 gene expression during postnatal development and in response to ischemia

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Glibenclamide is superior to decompressive craniectomy in a rat model of malignant stroke

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Molecular mechanisms of ischemic cerebral edema: role of electroneutral ion transport.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Cerebral microvascular endothelial cell Na/H exchange: evidence for the presence of NHE1 and NHE2 isoforms and regulation by arginine vasopressin

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

De novo expression of Trpm4 initiates secondary hemorrhage in spinal cord injury

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Protective effect of delayed treatment with low-dose glibenclamide in three models of ischemic stroke

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Roles of the cation-chloride cotransporters in neurological disease.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Brain endothelial cells and the glio-vascular complex

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Beyond NMDA and AMPA glutamate receptors: emerging mechanisms for ionic imbalance and cell death in stroke

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Safety of glyburide for gestational diabetes: a meta-analysis of pregnancy outcomes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Interactions of tight junctions with membrane channels and transporters

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Endothelial sulfonylurea receptor 1-regulated NC Ca-ATP channels mediate progressive hemorrhagic necrosis following spinal cord injury

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Non-selective cation channels, transient receptor potential channels and ischemic stroke

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Brain oedema in focal ischaemia: molecular pathophysiology and theoretical implications

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Transient receptor potential channels and intracellular signaling

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

TRPM2 is elevated in the tMCAO stroke model, transcriptionally regulated, and functionally expressed in C13 microglia.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

The role of TRP channels in oxidative stress-induced cell death

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

S-nitrosylation and permeation through connexin 43 hemichannels in astrocytes: induction by oxidant stress and reversal by reducing agents

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Physiology and pathophysiology of Na+/H+ exchange and Na+ -K+ -2Cl- cotransport in the heart, brain, and blood.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Vanilloid VR1 receptor is involved in rimonabant-induced neuroprotection

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

TRPMs and neuronal cell death.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Astrocytic swelling in cerebral ischemia as a possible cause of injury and target for therapy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

The role of Na-K-Cl co-transporter in cerebral ischemia

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Regulation of intracellular pH.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Neuroprotection in ischemia: blocking calcium-permeable acid-sensing ion channels.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

The role of sulphonylureas in the management of type 2 diabetes mellitus

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Increased apoptosis and inflammation after focal brain ischemia in mice lacking connexin43 in astrocytes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Extracellular acidosis increases neuronal cell calcium by activating acid-sensing ion channel 1a

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

A key role for TRPM7 channels in anoxic neuronal death

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Regulation and Modulation of pH in the Brain

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Why did NMDA receptor antagonists fail clinical trials for stroke and traumatic brain injury?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

An overview of inhibitors of Na(+)/H(+) exchanger

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Cellular function and control of volume-regulated anion channels

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Metabolic inhibition induces opening of unapposed connexin 43 gap junction hemichannels and reduces gap junctional communication in cortical astrocytes in culture

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Inhibition of Na+/H+ exchanger reduces infarct volume of focal cerebral ischemia in rats

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Receptor-mediated control of regulatory volume decrease (RVD) and apoptotic volume decrease (AVD).

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Induction of aquaporin-4 water channel mRNA after focal cerebral ischemia in rat.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Astroglia and glutamate in physiology and pathology: aspects on glutamate transport, glutamate-induced cell swelling and gap-junction communication

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Distribution of mRNA for vanilloid receptor subtype 1 (VR1), and VR1-like immunoreactivity, in the central nervous system of the rat and human

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

H(+)-gated cation channels

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

IL-6 secreted by astroglial cells regulates Na-K-Cl cotransport in brain microvessel endothelial cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Excitotoxicity and the NMDA receptor--still lethal after eight years

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Triggering and execution of neuronal death in brain ischaemia: two phases of glutamate release by different mechanisms

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Pharmacology, therapeutic efficacy, and adverse effects of bumetanide, a new "loop" diuretic

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

The plasma membrane sodium-hydrogen exchanger and its role in physiological and pathophysiological processes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Glutamate and the pathophysiology of hypoxic--ischemic brain damage

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Dynamics of interstitial and intracellular pH in evolving brain infarct

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Molecular cloning of putative members of the Na/H exchanger gene family. cDNA cloning, deduced amino acid sequence, and mRNA tissue expression of the rat Na/H exchanger NHE-1 and two structurally related proteins

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Open-channel block of N-methyl-D-aspartate (NMDA) responses by memantine: therapeutic advantage against NMDA receptor-mediated neurotoxicity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

28 September 2017

Excitotoxic cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Differential localization of Na+/H+ exchanger isoforms (NHE1 and NHE3) in polarized epithelial cell lines.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

DCPIB, a specific inhibitor of volume regulated anion channels (VRACs), reduces infarct size in MCAo and the release of glutamate in the ischemic cortical penumbra

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Memantine reduces neuronal dysfunctions triggered by in vitro ischemia and 3-nitropropionic acid

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Interleukin-1beta induces the expression of aquaporin-4 through a nuclear factor-kappaB pathway in rat astrocytes.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Decreased neuronal death in Na+/H+ exchanger isoform 1-null mice after in vitro and in vivo ischemia.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Capsaicin exhibits neuroprotective effects in a model of transient global cerebral ischemia in Mongolian gerbils.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Inhibition of TRPM2 function by PARP inhibitors protects cells from oxidative stress-induced death

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Inhibition of glutamate-induced delayed calcium deregulation by 2-APB and La3+ in cultured cortical neurones

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Functional coupling between sulfonylurea receptor type 1 and a nonselective cation channel in reactive astrocytes from adult rat brain.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Contribution of Na(+)-K(+)-Cl(-) cotransporter to high-[K(+)](o)- induced swelling and EAA release in astrocytes

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Alterations in the expression of the AQP family in cultured rat astrocytes during hypoxia and reoxygenation

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic stroke.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

A flow-activated chloride-selective membrane current in vascular endothelial cells

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Stimulation of Na+-K+-2Cl- cotransporter in neuronal cells by excitatory neurotransmitter glutamate.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Disruption of mitochondrial respiration inhibits volume-regulated anion channels and provokes neuronal cell swelling.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Calcium in ischemic cell death

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Na+/H+ exchangers of mammalian cells.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

pHi in piglet cerebral microvascular endothelial cells: recovery from an acid load

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

The neurotoxicity of excitatory amino acids is produced by passive chloride influx.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

A rapid redistribution of hydrogen ions is associated with depolarization and repolarization subsequent to cerebral ischemia reperfusion

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Microglial cells are a component of the perivascular glia limitans.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Blood to Brain Sodium Transport and Interstitial Fluid Potassium Concentration during Early Focal Ischemia in the Rat

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Endothelins activate Na+/H+ exchange in brain capillary endothelial cells via a high affinity endothelin-3 receptor that is not coupled to phospholipase C.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

NBQX, an AMPA antagonist, reduces glutamate-mediated brain edema

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Morphology and properties of astrocytes

31 May 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12975-013-0307-9

Contributions of ions and albumin to the formation and resolution of ischemic brain edema.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12975-013-0307-9

Changes in Na(+)-K(+)-Cl(-) cotransporter immunoreactivity in the gerbil hippocampus following transient ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12975-013-0307-9

Na+-K+-Cl- cotransporter in rat focal cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12975-013-0307-9

Inhibition of Na(+)-K(+)-Cl(-) cotransporter during focal cerebral ischemia decreases edema and neuronal damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12975-013-0307-9

Role of Cl- in cerebral vascular tone and expression of Na+-K+-2Cl- co-transporter after neonatal hypoxia-ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12975-013-0307-9

Na-K-Cl cotransporter-mediated intracellular Na+ accumulation affects Ca2+ signaling in astrocytes in an in vitro ischemic model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12975-013-0307-9

Moderate-to-severe ischemic conditions increase activity and phosphorylation of the cerebral microvascular endothelial cell Na+-K+-Cl- cotransporter.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12975-013-0307-9

Astrocytes from Na(+)-K(+)-Cl(-) cotransporter-null mice exhibit absence of swelling and decrease in EAA release

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12975-013-0307-9

Na(+)-dependent chloride transporter (NKCC1)-null mice exhibit less gray and white matter damage after focal cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12975-013-0307-9

Bumetanide inhibition of the blood-brain barrier Na-K-Cl cotransporter reduces edema formation in the rat middle cerebral artery occlusion model of stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12975-013-0307-9

Expression, immunolocalization, and functional activity of Na+/H+ exchanger isoforms in mouse endometrial epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12975-013-0307-9

Impaired regulation of pH homeostasis by oxidative stress in rat brain capillary endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12975-013-0307-9

Comparative changes in the blood-brain barrier and cerebral infarction of SHR and WKY rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12975-013-0307-9

Sodium transport from blood to brain: inhibition by furosemide and amiloride.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12975-013-0307-9

Na+/H+ exchange inhibitor SM-20220 improves endothelial dysfunction induced by ischemia-reperfusion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12975-013-0307-9

Relationship between the neuroprotective effect of Na+/H+ exchanger inhibitor SM-20220 and the timing of its administration in a transient middle cerebral artery occlusion model of rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12975-013-0307-9

Neurologic preservation by Na+-H+ exchange inhibition prior to 90 minutes of hypothermic circulatory arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12975-013-0307-9

Glutamate causes a loss in human cerebral endothelial barrier integrity through activation of NMDA receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12975-013-0307-9

Blockade of AMPA receptors reduces brain edema following opening of the blood-brain barrier.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12975-013-0307-9

Effects of a novel NMDA antagonist on experimental stroke rapidly and quantitatively assessed by diffusion-weighted MRI.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12975-013-0307-9

NGP1-01, a lipophilic polycyclic cage amine, is neuroprotective in focal ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12975-013-0307-9

The pre-ischaemic neuroprotective effect of a novel polyamine antagonist, N1-dansyl-spermine in a permanent focal cerebral ischaemia model in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12975-013-0307-9

Anoxia-evoked intracellular pH and Ca2+ concentration changes in cultured postnatal rat hippocampal neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12975-013-0307-9

Modulation of ASIC channels in rat cerebellar Purkinje neurons by ischaemia-related signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12975-013-0307-9

H(+)-gated cation channels: neuronal acid sensors in the NaC/DEG family of ion channels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12975-013-0307-9

Distribution, subcellular localization and ontogeny of ASIC1 in the mammalian central nervous system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12975-013-0307-9

Capsaicin activation of glutamatergic synaptic transmission in the rat locus coeruleus in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12975-013-0307-9

Massive accumulation of N-acylethanolamines after stroke. Cell signalling in acute cerebral ischemia?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12975-013-0307-9

Ischemia opens neuronal gap junction hemichannels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12975-013-0307-9

Alterations in metabolism and gap junction expression may determine the role of astrocytes as "good samaritans" or executioners.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12975-013-0307-9

Enhanced connexin 43 immunoreactivity in penumbral areas in the human brain following ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12975-013-0307-9

Gap-junction-mediated propagation and amplification of cell injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12975-013-0307-9

Ischemia-induced brain damage depends on specific gap-junctional coupling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12975-013-0307-9

Blockade of gap junctions in vivo provides neuroprotection after perinatal global ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12975-013-0307-9

Increased release of excitatory amino acids by the actions of ATP and peroxynitrite on volume-regulated anion channels (VRACs) in astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12975-013-0307-9

Volume-regulated anion channels are the predominant contributors to release of excitatory amino acids in the ischemic cortical penumbra

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12975-013-0307-9

Inhibition of ischemia-induced glutamate release in rat striatum by dihydrokinate and an anion channel blocker.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12975-013-0307-9

Roles of two types of anion channels in glutamate release from mouse astrocytes under ischemic or osmotic stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12975-013-0307-9

Quaternary ammonium compounds as water channel blockers. Specificity, potency, and site of action.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12975-013-0307-9

New potent inhibitors of aquaporins: silver and gold compounds inhibit aquaporins of plant and human origin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12975-013-0307-9

The role of hypoxia-inducible factor-1α, aquaporin-4, and matrix metalloproteinase-9 in blood-brain barrier disruption and brain edema after traumatic brain injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12975-013-0307-9

Aquaporin-4 facilitates reabsorption of excess fluid in vasogenic brain edema.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Acid-sensing ion channel 1 is localized in brain regions with high synaptic density and contributes to fear conditioning.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Na-K-Cl cotransporter contributes to glutamate-mediated excitotoxicity.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Global ischemia-induced increases in the gap junctional proteins connexin 32 (Cx32) and Cx36 in hippocampus and enhanced vulnerability of Cx32 knock-out mice.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Cell swelling and a nonselective cation channel regulated by internal Ca2+ and ATP in native reactive astrocytes from adult rat brain.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Stimulation of Na-K-2Cl cotransporter in neurons by activation of Non-NMDA ionotropic receptor and group-I mGluRs

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Functional demonstration of Na+-K+-2Cl- cotransporter activity in isolated, polarized choroid plexus cells.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Mechanisms of sodium transport at the blood-brain barrier studied with in situ perfusion of rat brain.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Glutamate neurotoxicity in cortical cell culture.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946359

Differential expression of volume-regulated anion channels during cell cycle progression of human cervical cancer cells

28 November 2018

1 reference

12 December 2020

Alterations in cerebral endothelial cell function in ischemia

1 reference

12 December 2020

Kinetic and pharmacological properties of human brain Na(+)/H(+) exchanger isoform 5 stably expressed in Chinese hamster ovary cells

1 reference

12 December 2020

Global Ischemia Induces Expression of Acid-Sensing Ion Channel 2a in Rat Brain

1 reference

12 December 2020

Role of connexin-based gap junction channels and hemichannels in ischemia-induced cell death in nervous tissue

1 reference

12 December 2020

The effect of endothelins on ion transport systems in cultured rat brain capillary endothelial cells

1 reference

12 December 2020

The volume-sensitive organic osmolyte-anion channel VSOAC is regulated by nonhydrolytic ATP binding

1 reference

12 December 2020

Extravasation of albumin in ischaemic brain oedema

1 reference

12 December 2020

Toxicologic Evaluation of Bumetanide, A Potent Diuretic Agent

1 reference

12 December 2020

[Expression of transient receptor potential channel 4 in striatum and hippocampus of rats is increased after focal cerebral ischemia]

1 reference

12 December 2020

Reduction of edema and infarction by Memantine and MK-801 after focal cerebral ischaemia and reperfusion in rat

1 reference

12 December 2020

10.1007/S12975-013-0307-9

Identifiers

DOI

1 reference

Dimensions Publication ID

1644672

1035591192

0 references

Fatcat ID

release_hdtm44k265etvl3ozj3vsjngia

0 references

1644672

1 reference

1 reference

1 reference