Dystrophin-deficient large animal models: translational research and exon skipping (Q26781901)

1

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Bo Bao

2

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Yusuke Echigoya

3

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Toshifumi Yokota

American Journal of Translational Research

4

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language of work or name

English

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publication date

2015

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published in

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volume

7

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issue

8

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page(s)

1314-31

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cites work

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Characterization of dystrophin deficient rats: a new model for Duchenne muscular dystrophy

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Quantitative phenotyping of Duchenne muscular dystrophy dogs by comprehensive gait analysis and overnight activity monitoring

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Antisense PMO found in dystrophic dog model was effective in cells from exon 7-deleted DMD patient

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Long-term efficacy of systemic multiexon skipping targeting dystrophin exons 45-55 with a cocktail of vivo-morpholinos in mdx52 mice

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Genetic modifiers of ambulation in the Cooperative International Neuromuscular Research Group Duchenne Natural History Study

28 September 2017

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The TREAT-NMD DMD Global Database: analysis of more than 7,000 Duchenne muscular dystrophy mutations

28 September 2017

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Predictive markers of clinical outcome in the GRMD dog model of Duchenne muscular dystrophy

28 September 2017

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A comparative anatomic and physiologic overview of the porcine heart.

28 September 2017

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Duchenne and Becker muscular dystrophies.

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Generation of muscular dystrophy model rats with a CRISPR/Cas system

28 September 2017

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Pharmacologic management of Duchenne muscular dystrophy: target identification and preclinical trials

28 September 2017

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A systematic review and meta-analysis on the epidemiology of Duchenne and Becker muscular dystrophy

28 September 2017

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What Can We Learn From Clinical Trials of Exon Skipping for DMD?

28 September 2017

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Diaphragm remodeling and compensatory respiratory mechanics in a canine model of Duchenne muscular dystrophy.

28 September 2017

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Skipping multiple exons of dystrophin transcripts using cocktail antisense oligonucleotides

28 September 2017

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Dystrophin insufficiency causes selective muscle histopathology and loss of dystrophin-glycoprotein complex assembly in pig skeletal muscle.

28 September 2017

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New developments in the use of gene therapy to treat Duchenne muscular dystrophy

28 September 2017

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Respiratory dysfunction in unsedated dogs with golden retriever muscular dystrophy

28 September 2017

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Development of multiexon skipping antisense oligonucleotide therapy for Duchenne muscular dystrophy

28 September 2017

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Anesthesia and Duchenne or Becker muscular dystrophy: review of 117 anesthetic exposures

28 September 2017

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Highly efficient in vivo delivery of PMO into regenerating myotubes and rescue in laminin-α2 chain-null congenital muscular dystrophy mice.

28 September 2017

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Initial pulmonary respiration causes massive diaphragm damage and hyper-CKemia in Duchenne muscular dystrophy dog.

28 September 2017

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Levels of α7 integrin and laminin-α2 are increased following prednisone treatment in the mdx mouse and GRMD dog models of Duchenne muscular dystrophy

28 September 2017

1 reference

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Factors influencing the efficiency of generating genetically engineered pigs by nuclear transfer: multi-factorial analysis of a large data set.

28 September 2017

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Bortezomib (PS-341) treatment decreases inflammation and partially rescues the expression of the dystrophin-glycoprotein complex in GRMD dogs

28 September 2017

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Genetically modified pig models for human diseases

28 September 2017

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Improvement of survival in Duchenne Muscular Dystrophy: retrospective analysis of 835 patients

28 September 2017

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Muscle function recovery in golden retriever muscular dystrophy after AAV1-U7 exon skipping.

28 September 2017

1 reference

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Extensive and prolonged restoration of dystrophin expression with vivo-morpholino-mediated multiple exon skipping in dystrophic dogs.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568789

Bodywide skipping of exons 45-55 in dystrophic mdx52 mice by systemic antisense delivery

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568789

A defect in dystrophin causes a novel porcine stress syndrome.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568789

MRI roadmap-guided transendocardial delivery of exon-skipping recombinant adeno-associated virus restores dystrophin expression in a canine model of Duchenne muscular dystrophy.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568789

Canine models of Duchenne muscular dystrophy and their use in therapeutic strategies

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568789

Long-term restoration of cardiac dystrophin expression in golden retriever muscular dystrophy following rAAV6-mediated exon skipping

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568789

Cardiomyopathy of Duchenne muscular dystrophy: current understanding and future directions

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568789

Mammalian models of Duchenne Muscular Dystrophy: pathological characteristics and therapeutic applications

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568789

Antisense oligo-mediated multiple exon skipping in a dog model of duchenne muscular dystrophy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568789

Golden retriever muscular dystrophy (GRMD): Developing and maintaining a colony and physiological functional measurements

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568789

In-frame dystrophin following exon 51-skipping improves muscle pathology and function in the exon 52-deficient mdx mouse

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568789

An intronic LINE-1 element insertion in the dystrophin gene aborts dystrophin expression and results in Duchenne-like muscular dystrophy in the corgi breed

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568789

Current status and applications of somatic cell nuclear transfer in dogs

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568789

Effect of epigenetic regulation during swine embryogenesis and on cloning by nuclear transfer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568789

Chronic administration of membrane sealant prevents severe cardiac injury and ventricular dilatation in dystrophic dogs

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568789

A duchenne muscular dystrophy gene hot spot mutation in dystrophin-deficient cavalier king charles spaniels is amenable to exon 51 skipping

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568789

Mutational spectrum of DMD mutations in dystrophinopathy patients: application of modern diagnostic techniques to a large cohort

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568789

Mammalian animal models for Duchenne muscular dystrophy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568789

A renaissance for antisense oligonucleotide drugs in neurology: exon skipping breaks new ground

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568789

Follow-up of three patients with a large in-frame deletion of exons 45-55 in the Duchenne muscular dystrophy (DMD) gene

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568789

Comparative analysis of antisense oligonucleotide sequences for targeted skipping of exon 51 during dystrophin pre-mRNA splicing in human muscle

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568789

Potential of oligonucleotide-mediated exon-skipping therapy for Duchenne muscular dystrophy.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568789

Cardiac involvement in Beagle-based canine X-linked muscular dystrophy in Japan (CXMDJ): electrocardiographic, echocardiographic, and morphologic studies

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568789

Molecular analysis of a spontaneous dystrophin 'knockout' dog.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568789

Induction of exon skipping of the dystrophin transcript in lymphoblastoid cells by transfecting an antisense oligodeoxynucleotide complementary to an exon recognition sequence

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568789

Duchenne muscular dystrophy: Pathogenetic aspects and genetic prevention

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568789

Progressive muscular dystrophy in a golden retriever dog: light microscope and ultrastructural features at 4 and 8 months

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568789

Feline muscular dystrophy with dystrophin deficiency

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568789

Development of Duchenne-type cardiomyopathy. Morphologic studies in a canine model.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568789

Segregation analysis of 1885 DMD families: significant departure from the expected proportion of sporadic cases

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568789

Bradykinin restores left ventricular function, sarcomeric protein phosphorylation, and e/nNOS levels in dogs with Duchenne muscular dystrophy cardiomyopathy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568789

Canine X-linked muscular dystrophy. An animal model of Duchenne muscular dystrophy: clinical studies.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568789

Duchenne's cardiomyopathy in a canine model: electrocardiographic and echocardiographic studies

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568789

Dystrophin-deficient muscular dystrophy in two lurcher siblings.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568789

Dystrophin-deficient muscular dystrophy in a Norfolk terrier.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568789

Emergent presentation of a cat with dystrophin-deficient muscular dystrophy

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568789

Dystrophin-deficient pigs provide new insights into the hierarchy of physiological derangements of dystrophic muscle

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568789

Hypertrophic muscular dystrophy in a young dog.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568789

The Pathology of Paralysis with Muscular Degeneration (Paralysie Myosclerotique), or Paralysis with Apparent Hypertrophy.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568789

Identification of three distinguishable phenotypes in golden retriever muscular dystrophy.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568789

Efficacy of systemic morpholino exon-skipping in Duchenne dystrophy dogs

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568789

Canine X-linked muscular dystrophy in a family of Grand Basset Griffon Vendéen dogs.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568789

Serial cloning of pigs by somatic cell nuclear transfer: restoration of phenotypic normality during serial cloning.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568789

Tissue Doppler imaging for detection of radial and longitudinal myocardial dysfunction in a family of cats affected by dystrophin-deficient hypertrophic muscular dystrophy.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568789

Targeted exon skipping as a potential gene correction therapy for Duchenne muscular dystrophy.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568789

Micro-dystrophin cDNA ameliorates dystrophic phenotypes when introduced into mdx mice as a transgene

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568789

Dystrophin-deficient muscular dystrophy in a Labrador retriever

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568789

Muscle lesions associated with dystrophin deficiency in neonatal golden retriever puppies

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568789

Muscular dystrophy in female dogs

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568789

Lethal peracute rhabdomyolysis associated with stress and general anesthesia in three dystrophin-deficient cats.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4568789

Cardiomyopathy in dystrophin-deficient hypertrophic feline muscular dystrophy

28 November 2018

1 reference

12 December 2020

Contraction force generated by tarsal joint flexion and extension in dogs with golden retriever muscular dystrophy

1 reference

12 December 2020

Mast cell proliferation and alterations in bFGF amount and localization are involved in the response of muscle to dystrophin deficiency in hypertrophic feline dystrophy

1 reference

12 December 2020

Changes of skeletal muscle in young dystrophin-deficient cats: a morphological and morphometric study

1 reference

12 December 2020

Restoration of dystrophin expression in cultured hybrid myotubes

1 reference

12 December 2020

Fibrogenic cytokines and extent of fibrosis in muscle of dogs with X-linked golden retriever muscular dystrophy

1 reference

12 December 2020

Canine X-linked muscular dystrophy in Japan (CXMDJ)

1 reference

12 December 2020

The cranial sartorius muscle undergoes true hypertrophy in dogs with golden retriever muscular dystrophy

1 reference

12 December 2020

Dystrophin deficiency causes lethal muscle hypertrophy in cats

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12 December 2020

Electrodiagnostic evaluation in feline hypertrophic muscular dystrophy

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12 December 2020

An error in dystrophin mRNA processing in golden retriever muscular dystrophy, an animal homologue of Duchenne muscular dystrophy

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12 December 2020

Dystrophin-deficient muscular dystrophy in an old English sheepdog

1 reference

12 December 2020

Major clinical and histopathological characteristics of canine X-linked muscular dystrophy in Japan, CXMDJ

1 reference

12 December 2020

Multiexon skipping leading to an artificial DMD protein lacking amino acids from exons 45 through 55 could rescue up to 63% of patients with Duchenne muscular dystrophy

1 reference

12 December 2020

Dystrophin-deficient muscular dystrophy in a Weimaraner

1 reference

12 December 2020

Selective vacuolar degeneration in dystrophin-deficient canine Purkinje fibers despite preservation of dystrophin-associated proteins with overexpression of Dp71

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12 December 2020

Ringo, a Golden Retriever Muscular Dystrophy (GRMD) dog with absent dystrophin but normal strength

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12 December 2020

Muscular dystrophy in dogs: does the crossing of breeds influence disease phenotype?

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12 December 2020

Dystrophin-deficient muscular dystrophy in an Alaskan malamute

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12 December 2020

Evidence-based path to newborn screening for Duchenne muscular dystrophy

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12 December 2020

Muscular dystrophy in a dog resembling human becker muscular dystrophy

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12 December 2020

Current treatment and management of dystrophinopathies

1 reference

12 December 2020

Muscular dystrophy in the Japanese Spitz: an inversion disrupts the DMD and RPGR genes

1 reference

12 December 2020

Myopathy with a Possible Recessive X-Linked Inheritance in a Litter of Irish Terriers

1 reference

12 December 2020

Sporadic occurrence of Duchenne muscular dystrophy: evidence for new mutation

1 reference

12 December 2020

Deletion of the dystrophin muscle promoter in feline muscular dystrophy

1 reference

12 December 2020

Duchenne muscular dystrophy gene therapy in the canine model

1 reference

12 December 2020

Identifiers

3488873

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference