Cellular and molecular biology of small cell lung cancer: an overview (Q26767029)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26958489%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

title

Cellular and molecular biology of small cell lung cancer: an overview (English)

1 reference

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10 March 2020

0 references

1 reference

2

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10 March 2020

Emilio Bria

4

1 reference

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10 March 2020

author name string

Niki Karachaliou

1

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10 March 2020

Chiara Lazzari

3

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10 March 2020

Filippo de Marinis

5

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10 March 2020

Rafael Rosell

6

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10 March 2020

language of work or name

English

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publication date

1 February 2016

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Translational lung cancer research

10 March 2020

published in

2 references

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10 March 2020

volume

5

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10 March 2020

issue

1

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10 March 2020

page(s)

2-15

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Novel therapies in small cell lung cancer

10 March 2020

cites work

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Cancer immunology. Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer

7 April 2017

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7 April 2017

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Identification of bronchioalveolar stem cells in normal lung and lung cancer

7 April 2017

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Mammalian achaete-scute homolog 1 is required for the early development of olfactory and autonomic neurons

7 April 2017

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NOTCH, ASCL1, p53 and RB alterations define an alternative pathway driving neuroendocrine and small cell lung carcinomas

7 April 2017

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A DLL3-targeted antibody-drug conjugate eradicates high-grade pulmonary neuroendocrine tumor-initiating cells in vivo

28 September 2017

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28 September 2017

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Fibroblast Growth Factor Receptor 1 and Related Ligands in Small-Cell Lung Cancer

28 September 2017

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A phase 1 safety study of veliparib combined with cisplatin and etoposide in extensive stage small cell lung cancer: A trial of the ECOG-ACRIN Cancer Research Group (E2511).

28 September 2017

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Adoptive cell transfer as personalized immunotherapy for human cancer

28 September 2017

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RB loss in resistant EGFR mutant lung adenocarcinomas that transform to small-cell lung cancer

28 September 2017

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DNA methylation in small cell lung cancer defines distinct disease subtypes and correlates with high expression of EZH2.

28 September 2017

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Assessment of ABT-263 activity across a cancer cell line collection leads to a potent combination therapy for small-cell lung cancer.

28 September 2017

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28 September 2017

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28 September 2017

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Targeting transcriptional addictions in small cell lung cancer with a covalent CDK7 inhibitor

28 September 2017

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28 September 2017

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Poly (ADP) ribose polymerase enzyme inhibitor, veliparib, potentiates chemotherapy and radiation in vitro and in vivo in small cell lung cancer.

28 September 2017

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Therapeutic priority of the PI3K/AKT/mTOR pathway in small cell lung cancers as revealed by a comprehensive genomic analysis

28 September 2017

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28 September 2017

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Frequent mutations in chromatin-remodelling genes in pulmonary carcinoids

28 September 2017

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Genetic and clonal dissection of murine small cell lung carcinoma progression by genome sequencing

28 September 2017

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CD133+ cancer stem-like cells in small cell lung cancer are highly tumorigenic and chemoresistant but sensitive to a novel neuropeptide antagonist

28 September 2017

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A genomics-based classification of human lung tumors

28 September 2017

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Proteomic markers of DNA repair and PI3K pathway activation predict response to the PARP inhibitor BMN 673 in small cell lung cancer

28 September 2017

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Predictive value of BRCA1, ERCC1, ATP7B, PKM2, TOPOI, TOPΟ-IIA, TOPOIIB and C-MYC genes in patients with small cell lung cancer (SCLC) who received first line therapy with cisplatin and etoposide

28 September 2017

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NeuroD1 regulation of migration accompanies the differential sensitivity of neuroendocrine carcinomas to TrkB inhibition

28 September 2017

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EZH2 promotes E2F-driven SCLC tumorigenesis through modulation of apoptosis and cell-cycle regulation

28 September 2017

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Selective tropism of Seneca Valley virus for variant subtype small cell lung cancer.

28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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Multicentre phase II study of cisplatin-etoposide chemotherapy for advanced large-cell neuroendocrine lung carcinoma: the GFPC 0302 study

28 September 2017

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Functional characterization of pulmonary neuroendocrine cells in lung development, injury, and tumorigenesis

28 September 2017

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Proteomic profiling identifies dysregulated pathways in small cell lung cancer and novel therapeutic targets including PARP1.

28 September 2017

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Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer

28 September 2017

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Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer

28 September 2017

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Multidirectional differentiation of Achaete-Scute homologue-1-defined progenitors in lung development and injury repair

28 September 2017

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Achaete-scute homologue-1 (ASH1) stimulates migration of lung cancer cells through Cdk5/p35 pathway.

28 September 2017

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Phase II study of single-agent navitoclax (ABT-263) and biomarker correlates in patients with relapsed small cell lung cancer

28 September 2017

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Phase II trial of temozolomide in patients with relapsed sensitive or refractory small cell lung cancer, with assessment of methylguanine-DNA methyltransferase as a potential biomarker

28 September 2017

1 reference

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Update on small cell carcinoma and its differentiation from squamous cell carcinoma and other non-small cell carcinomas

28 September 2017

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A crucial requirement for Hedgehog signaling in small cell lung cancer

28 September 2017

1 reference

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Characterization of the cell of origin for small cell lung cancer

28 September 2017

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Nuclear factor I/B is an oncogene in small cell lung cancer

28 September 2017

1 reference

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Phase I study of Navitoclax (ABT-263), a novel Bcl-2 family inhibitor, in patients with small-cell lung cancer and other solid tumors

28 September 2017

1 reference

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Notch inhibition by the ligand DELTA-LIKE 3 defines the mechanism of abnormal vertebral segmentation in spondylocostal dysostosis.

28 September 2017

1 reference

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Neuroendocrine tumors of the lung: an update

28 September 2017

1 reference

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Advances in neuroendocrine lung tumors

28 September 2017

1 reference

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Cell of origin of lung cancer.

28 September 2017

1 reference

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CD47 is an adverse prognostic factor and therapeutic antibody target on human acute myeloid leukemia stem cells.

28 September 2017

1 reference

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Patients with lung cancer and paraneoplastic Hu syndrome harbor HuD-specific type 2 CD8+ T cells

28 September 2017

1 reference

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Achaete-scute complex homologue 1 regulates tumor-initiating capacity in human small cell lung cancer.

28 September 2017

1 reference

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Immunohistochemical expression of basic fibroblast growth factor and fibroblast growth factor receptors 1 and 2 in the pathogenesis of lung cancer

28 September 2017

1 reference

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Targeting the neural cell adhesion molecule in cancer

28 September 2017

1 reference

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Divergent functions and distinct localization of the Notch ligands DLL1 and DLL3 in vivo

28 September 2017

1 reference

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Tumor suppressor role of Notch-1 signaling in neuroendocrine tumors.

28 September 2017

1 reference

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Fast, hungry and unstable: finding the Achilles' heel of small-cell lung cancer

28 September 2017

1 reference

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Phase III study of adjuvant vaccination with Bec2/bacille Calmette-Guerin in responding patients with limited-disease small-cell lung cancer (European Organisation for Research and Treatment of Cancer 08971-08971B; Silva Study).

28 September 2017

1 reference

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Stem cells for lung cancer?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758976

Direct interactions among Ret, GDNF and GFRalpha1 molecules reveal new insights into the assembly of a functional three-protein complex

28 September 2017

1 reference

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Achaete-scute homolog-1 and Notch in lung neuroendocrine development and cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758976

Basal cells are a multipotent progenitor capable of renewing the bronchial epithelium

28 September 2017

1 reference

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Paraneoplastic Syndromes Involving the Nervous System

28 September 2017

1 reference

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Oat-cell carcinoma of the bronchus

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758976

Small cell lung carcinoma (SCLC): a clinicopathologic study of 100 cases with surgical specimens

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758976

Heterogeneity of so-called neuroendocrine lung tumors

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758976

Neuroepithelial bodies of pulmonary airways serve as a reservoir of progenitor cells capable of epithelial regeneration

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758976

Anti-Hu--associated paraneoplastic encephalomyelitis/sensory neuronopathy. A clinical study of 71 patients

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758976

PD-L1 expression in small cell neuroendocrine carcinomas

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758976

RET mutations in neuroendocrine tumors: including small-cell lung cancer

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758976

Targeted disruption of the EZH2-EED complex inhibits EZH2-dependent cancer

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758976

Ascl1 and Neurog2 form novel complexes and regulate Delta-like3 (Dll3) expression in the neural tube

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758976

Two prognostically significant subtypes of high-grade lung neuroendocrine tumours independent of small-cell and large-cell neuroendocrine carcinomas identified by gene expression profiles.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758976

Decrease of interleukin-2 secretion is a new independent prognostic factor associated with poor survival in patients with small-cell lung cancer.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758976

Expression of bcl-2 in small cell lung carcinoma cells.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758976

Small cell carcinomas of the lung express the Bcl-2 protein

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758976

myc family DNA amplification in small cell lung cancer patients' tumors and corresponding cell lines

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758976

Immunohistological detection of fucosyl-GM1 ganglioside in human lung cancer and normal tissues with monoclonal antibodies

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758976

Significance of programmed cell death-ligand 1 expression and its association with survival in patients with small cell lung cancer.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758976

Fibroblast growth factor receptor 1 (FGFR1) amplification is a potential therapeutic target in small-cell lung cancer.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758976

Ipilimumab in combination with paclitaxel and carboplatin as first-line therapy in extensive-disease-small-cell lung cancer: results from a randomized, double-blind, multicenter phase 2 trial

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758976

Cell of origin of small cell lung cancer: inactivation of Trp53 and Rb1 in distinct cell types of adult mouse lung.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758976

Distinction of pulmonary large cell neuroendocrine carcinoma from small cell lung carcinoma: a morphological, immunohistochemical, and molecular analysis.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758976

Role of chemotherapy and the receptor tyrosine kinases KIT, PDGFRalpha, PDGFRbeta, and Met in large-cell neuroendocrine carcinoma of the lung

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758976

Vaccination of patients with small-cell lung cancer with synthetic fucosyl GM-1 conjugated to keyhole limpet hemocyanin

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758976

Cytokeratin 7 and cytokeratin 20 expression in epithelial neoplasms: a survey of 435 cases

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758976

PTEN/MMAC1 mutations identified in small cell, but not in non-small cell lung cancers.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758976

The spectrum of immunohistochemical staining of small-cell lung carcinoma in specimens from transbronchial and open-lung biopsies.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758976

L-myc, a new myc-related gene amplified and expressed in human small cell lung cancer

28 November 2018

1 reference

12 December 2020

ERCC1 and Ki67 in small cell lung carcinoma and other neuroendocrine tumors of the lung: distribution and impact on survival

1 reference

12 December 2020

Thyroid transcription factor-1 is expressed in extrapulmonary small cell carcinomas but not in other extrapulmonary neuroendocrine tumors

1 reference

12 December 2020

Long survival of patients with small cell lung cancer after adjuvant treatment with the anti-idiotypic antibody BEC2 plus Bacillus Calmette-Guérin

1 reference

12 December 2020

Ganglioside expression in lung cancer cell lines

1 reference

12 December 2020

Immunization of melanoma patients with BEC2 anti-idiotypic monoclonal antibody that mimics GD3 ganglioside: enhanced immunogenicity when combined with adjuvant

1 reference

12 December 2020

Expression of bcl-2 oncogene protein is prevalent in small cell lung carcinomas

1 reference

12 December 2020

The P16/cyclin D1/Rb pathway in neuroendocrine tumors of the lung

1 reference

12 December 2020

Histological lung cancer types. A morphological and biological correlation

1 reference

12 December 2020

A genetic snapshot of small cell lung cancer

1 reference

12 December 2020

Human ret proto-oncogene mapped to chromosome 10q11.2.

1 reference

12 December 2020

Reciprocal CD4+ T-cell balance of effector CD62Llow CD4+ and CD62LhighCD25+ CD4+ regulatory T cells in small cell lung cancer reflects disease stage

1 reference

12 December 2020

Stem cells in lung biology

1 reference

12 December 2020

Combination of p53 cancer vaccine with chemotherapy in patients with extensive stage small cell lung cancer

1 reference

12 December 2020

Induction of small cell lung cancer by somatic inactivation of both Trp53 and Rb1 in a conditional mouse model

1 reference

12 December 2020

Constitutive achaete-scute homologue-1 promotes airway dysplasia and lung neuroendocrine tumors in transgenic mice

1 reference

12 December 2020

10.3978/J.ISSN.2218-6751.2016.01.02

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26958489%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26958489%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

1 reference