Cysteine Proteases: Modes of Activation and Future Prospects as Pharmacological Targets (Q26747530)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27199750%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

review article

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title

Cysteine Proteases: Modes of Activation and Future Prospects as Pharmacological Targets (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27199750%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

1 reference

2

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2 April 2020

author name string

Sonia Verma

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27199750%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Kailash C Pandey

series ordinal

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27199750%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

language of work or name

English

0 references

publication date

25 April 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27199750%20AND%20SRC:MED&resulttype=core&format=json

Frontiers in Pharmacology

2 April 2020

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27199750%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

volume

7

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2 April 2020

page(s)

107

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27199750%20AND%20SRC:MED&resulttype=core&format=json

The proteome of lysosomes

2 April 2020

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Cysteine cathepsins: from structure, function and regulation to new frontiers

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The crystal and molecular structures of a cathepsin K:chondroitin sulfate complex

7 April 2017

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Structural and Functional Relationships in the Virulence-associated Cathepsin L Proteases of the Parasitic Liver Fluke, Fasciola hepatica

7 April 2017

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Crystal structure of human procathepsin X: a cysteine protease with the proregion covalently linked to the active site cysteine

7 April 2017

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Crystal structure of wild-type human procathepsin K

7 April 2017

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Structure of rat procathepsin B: model for inhibition of cysteine protease activity by the proregion

7 April 2017

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Crystal structures of human procathepsin B at 3.2 and 3.3 Angstroms resolution reveal an interaction motif between a papain-like cysteine protease and its propeptide

7 April 2017

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7 April 2017

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The Ionic and hydrophobic interactions are required for the auto activation of cysteine proteases of Plasmodium falciparum

7 April 2017

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Autocatalytic processing of recombinant human procathepsin L. Contribution of both intermolecular and unimolecular events in the processing of procathepsin L in vitro

7 April 2017

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7 April 2017

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Structure-function of falcipains: malarial cysteine proteases

28 September 2017

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Falcipains and other cysteine proteases of malaria parasites

28 September 2017

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Secreted cysteine proteases of the carcinogenic liver fluke, Opisthorchis viverrini: regulation of cathepsin F activation by autocatalysis and trans-processing by cathepsin B

28 September 2017

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28 September 2017

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28 September 2017

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Regulatory elements within the prodomain of Falcipain-2, a cysteine protease of the malaria parasite Plasmodium falciparum

28 September 2017

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Hemoglobin cleavage site-specificity of the Plasmodium falciparum cysteine proteases falcipain-2 and falcipain-3.

28 September 2017

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The importance of pH in regulating the function of the Fasciola hepatica cathepsin L1 cysteine protease

28 September 2017

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Autocatalytic processing of procathepsin B is triggered by proenzyme activity

28 September 2017

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The origin and evolution of plant cystatins and their target cysteine proteinases indicate a complex functional relationship

28 September 2017

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Nelfinavir, A lead HIV protease inhibitor, is a broad-spectrum, anticancer agent that induces endoplasmic reticulum stress, autophagy, and apoptosis in vitro and in vivo

28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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31 May 2018

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31 May 2018

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31 May 2018

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31 May 2018

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Human recombinant pro-dipeptidyl peptidase I (cathepsin C) can be activated by cathepsins L and S but not by autocatalytic processing

21 January 2018

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Cathepsin K is involved in development of psoriasis-like skin lesions through TLR-dependent Th17 activation

21 January 2018

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Conformational flexibility and allosteric regulation of cathepsin K.

21 January 2018

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Independent intramolecular mediators of folding, activity, and inhibition for the Plasmodium falciparum cysteine protease falcipain-2.

21 January 2018

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Comprehensive search for cysteine cathepsins in the human genome

21 January 2018

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Binding of chondroitin 4-sulfate to cathepsin S regulates its enzymatic activity.

21 January 2018

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Gene disruptions demonstrate independent roles for the four falcipain cysteine proteases of Plasmodium falciparum

21 January 2018

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Folding of the Plasmodium falciparum cysteine protease falcipain-2 is mediated by a chaperone-like peptide and not the prodomain

21 January 2018

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Falcipain cysteine proteases require bipartite motifs for trafficking to the Plasmodium falciparum food vacuole

21 January 2018

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Recombinant human procathepsin S is capable of autocatalytic processing at neutral pH in the presence of glycosaminoglycans

21 January 2018

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Maturation of human procathepsin B. Proenzyme activation and proteolytic processing of the precursor to the mature proteinase, in vitro, are primarily unimolecular processes.

21 January 2018

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Processing of the papain precursor. The ionization state of a conserved amino acid motif within the Pro region participates in the regulation of intramolecular processing.

28 November 2018

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Evidence that aspartic proteinase is involved in the proteolytic processing event of procathepsin L in lysosomes

28 November 2018

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12 December 2020

The cysteine proteinases of Schistosoma mansoni cercariae

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12 December 2020

Effect of protease inhibitors on angiotensin-converting enzyme activity in human T-lymphocytes

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12 December 2020

Collagenolytic activity of cathepsin K is specifically modulated by cartilage-resident chondroitin sulfates

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Schistosome asparaginyl endopeptidase SM32 in hemoglobin digestion

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12 December 2020

Protein-protein interaction inhibitors get into the groove

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The Autoactivation of Trypsinogen

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Potency and selectivity of the cathepsin L propeptide as an inhibitor of cysteine proteases

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Cysteine proteinase activity regulation. A possible role of heparin and heparin-like glycosaminoglycans

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Activating the cathepsin B1 of a parasite: a major route with alternative pathways?

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Structural basis for specificity of papain-like cysteine protease proregions toward their cognate enzymes

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12 December 2020

Identifiers

DOI

10.3389/FPHAR.2016.00107

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27199750%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27199750%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27199750%20AND%20SRC:MED&resulttype=core&format=json