The Plasmodium falciparum cysteine protease falcipain-2 captures its substrate, hemoglobin, via a unique motif (Q33878982)

29 July 2017

The Plasmodium falciparum cysteine protease falcipain-2 captures its substrate, hemoglobin, via a unique motif (English)

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29 July 2017

Plasmodium falciparum

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6

Philip J Rosenthal

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5

James H McKerrow

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29 July 2017

Kailash C Pandey

1

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29 July 2017

Stephanie X Wang

series ordinal

2

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29 July 2017

Puran S Sijwali

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3

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29 July 2017

Anthony L Lau

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4

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29 July 2017

language of work or name

English

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publication date

17 June 2005

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Proceedings of the National Academy of Sciences of the United States of America

29 July 2017

6

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based on heuristic

inferred from page(s)

published in

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102

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26

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9138-9143

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Cysteine proteases of malaria parasites

29 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1166610

A Plasmodium falciparum dipeptidyl aminopeptidase I participates in vacuolar hemoglobin degradation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1166610

Plasmodium falciparum cysteine protease falcipain-1 is not essential in erythrocytic stage malaria parasites

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1166610

Antimalarial drug resistance

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1166610

Gene disruption confirms a critical role for the cysteine protease falcipain-2 in hemoglobin hydrolysis by Plasmodium falciparum

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1166610

Antimalarial drug discovery: old and new approaches

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1166610

Data-mining approaches reveal hidden families of proteases in the genome of malaria parasite

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1166610

Structure-activity relationships for inhibition of cysteine protease activity and development of Plasmodium falciparum by peptidyl vinyl sulfones

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1166610

Biological roles of proteases in parasitic protozoa

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1166610

Collagenase activity of cathepsin K depends on complex formation with chondroitin sulfate

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1166610

Expression and characterization of the Plasmodium falciparum haemoglobinase falcipain-3

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1166610

Homophilic complex formation of MT1-MMP facilitates proMMP-2 activation on the cell surface and promotes tumor cell invasion.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1166610

The ears of the hippopotamus: manifestations, determinants, and estimates of the malaria burden

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1166610

Characterization of native and recombinant falcipain-2, a principal trophozoite cysteine protease and essential hemoglobinase of Plasmodium falciparum

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1166610

Matrix metalloproteinases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1166610

Characterization of novel cathepsin K mutations in the pro and mature polypeptide regions causing pycnodysostosis.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1166610

Hemoglobin metabolism in the malaria parasite Plasmodium falciparum

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1166610

Inhibition of a Plasmodium vinckei cysteine proteinase cures murine malaria

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1166610

Site-directed mutagenesis by overlap extension using the polymerase chain reaction

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1166610

Crystal structure of the thrombin-hirudin complex: a novel mode of serine protease inhibition

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1166610

Antimalarial effects of peptide inhibitors of a Plasmodium falciparum cysteine proteinase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1166610

Excess hemoglobin digestion and the osmotic stability of Plasmodium falciparum-infected red blood cells.

5 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0502368102

Antimalarial effects in mice of orally administered peptidyl cysteine protease inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0502368102

Targeted disruption of Plasmodium falciparum cysteine protease, falcipain 1, reduces oocyst production, not erythrocytic stage growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0502368102

Enzymic, phylogenetic, and structural characterization of the unusual papain-like protease domain of Plasmodium falciparum SERA5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0502368102

Folding of the Plasmodium falciparum cysteine protease falcipain-2 is mediated by a chaperone-like peptide and not the prodomain

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0502368102

Independent intramolecular mediators of folding, activity, and inhibition for the Plasmodium falciparum cysteine protease falcipain-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0502368102

Systematic optimization of expression and refolding of the Plasmodium falciparum cysteine protease falcipain-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0502368102

Determination of the rate constant of enzyme modification by measuring the substrate reaction in the presence of the modifier.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0502368102

Recombinant falcipain-2 cleaves erythrocyte membrane ankyrin and protein 4.1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0502368102

21 January 2018

Identifiers

DOI

10.1073/PNAS.0502368102

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29 July 2017

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29 July 2017

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