Exosomal miRNAs as cancer biomarkers and therapeutic targets (Q26738660)

Journal of extracellular vesicles

Europe PubMed Central

title

Exosomal miRNAs as cancer biomarkers and therapeutic targets (English)

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Arron Thind

1

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Clive Wilson

series ordinal

2

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language of work or name

English

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publication date

2016

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published in

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Cancer exosomes perform cell-independent microRNA biogenesis and promote tumorigenesis

volume

5

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issue

0

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page(s)

31292

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cites work

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7 April 2017

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MicroRNA expression profiling of human breast cancer identifies new markers of tumor subtype

7 April 2017

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7 April 2017

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Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells

7 April 2017

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7 April 2017

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Sumoylated hnRNPA2B1 controls the sorting of miRNAs into exosomes through binding to specific motifs

7 April 2017

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7 April 2017

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7 April 2017

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MicroRNAs bind to Toll-like receptors to induce prometastatic inflammatory response

7 April 2017

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7 April 2017

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The microRNA spectrum in 12 body fluids

7 April 2017

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Exosomal microRNA: a diagnostic marker for lung cancer

7 April 2017

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MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer

7 April 2017

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Ceramide triggers budding of exosome vesicles into multivesicular endosomes

7 April 2017

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microRNAs as oncogenes and tumor suppressors

7 April 2017

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Activated platelets release two types of membrane vesicles: microvesicles by surface shedding and exosomes derived from exocytosis of multivesicular bodies and alpha-granules

7 April 2017

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Membrane transport in the endocytic pathway

7 April 2017

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Isolation of biologically active and morphologically intact exosomes from plasma of patients with cancer

7 April 2017

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Isolation of Exosomes from Blood Plasma: Qualitative and Quantitative Comparison of Ultracentrifugation and Size Exclusion Chromatography Methods

28 September 2017

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Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth

28 September 2017

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Extracellular vesicle-mediated transfer of functional RNA in the tumor microenvironment.

28 September 2017

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Serum Exosome MicroRNA as a Minimally-Invasive Early Biomarker of AML.

28 September 2017

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In Vivo imaging reveals extracellular vesicle-mediated phenocopying of metastatic behavior

28 September 2017

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Endothelial exosomes contribute to the antitumor response during breast cancer neoadjuvant chemotherapy via microRNA transfer

28 September 2017

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Ready-made chromatography columns for extracellular vesicle isolation from plasma

28 September 2017

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Exosome-mediated transfer of miR-10b promotes cell invasion in breast cancer.

28 September 2017

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Increased serum levels of circulating exosomal microRNA-373 in receptor-negative breast cancer patients

28 September 2017

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Exosomal miR-135b shed from hypoxic multiple myeloma cells enhances angiogenesis by targeting factor-inhibiting HIF-1.

28 September 2017

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Quantitative and stoichiometric analysis of the microRNA content of exosomes

28 September 2017

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Cellular disposal of miR23b by RAB27-dependent exosome release is linked to acquisition of metastatic properties

28 September 2017

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Exosomal miR-1290 and miR-375 as prognostic markers in castration-resistant prostate cancer

28 September 2017

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Integrated immunoisolation and protein analysis of circulating exosomes using microfluidic technology

28 September 2017

1 reference

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Neoadjuvant Chemotherapy in Breast Cancer Patients Induces miR-34a and miR-122 Expression

28 September 2017

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miR-34a is an intracellular and exosomal predictive biomarker for response to docetaxel with clinical relevance to prostate cancer progression

28 September 2017

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Cell-cell communication in the tumor microenvironment, carcinogenesis, and anticancer treatment.

28 September 2017

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Tumor-derived exosomes promote tumor progression and T-cell dysfunction through the regulation of enriched exosomal microRNAs in human nasopharyngeal carcinoma

28 September 2017

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Microfluidic device (ExoChip) for on-chip isolation, quantification and characterization of circulating exosomes

28 September 2017

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Ionizing radiation and glioblastoma exosomes: implications in tumor biology and cell migration

28 September 2017

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MicroRNA and protein profiling of brain metastasis competent cell-derived exosomes

28 September 2017

1 reference

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Analysis of serum exosomal microRNAs and clinicopathologic features of patients with pancreatic adenocarcinoma

28 September 2017

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What is next generation sequencing?

28 September 2017

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Association of circulating miR-223 and miR-16 with disease activity in patients with early rheumatoid arthritis.

28 September 2017

1 reference

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Role of pancreatic cancer-derived exosomes in salivary biomarker development

28 September 2017

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Ciliated micropillars for the microfluidic-based isolation of nanoscale lipid vesicles.

28 September 2017

1 reference

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The pre-metastatic niche: finding common ground

28 September 2017

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Neutral sphingomyelinase 2 (nSMase2)-dependent exosomal transfer of angiogenic microRNAs regulate cancer cell metastasis

28 September 2017

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Serum microRNA expression profile: miR-1246 as a novel diagnostic and prognostic biomarker for oesophageal squamous cell carcinoma

28 September 2017

1 reference

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Clinical impact of serum exosomal microRNA-21 as a clinical biomarker in human esophageal squamous cell carcinoma

28 September 2017

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Exosome can prevent RNase from degrading microRNA in feces

28 September 2017

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Leukemia cell to endothelial cell communication via exosomal miRNAs.

28 September 2017

1 reference

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Exosome removal as a therapeutic adjuvant in cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4954869

Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4954869

Isolation of exosomes for subsequent mRNA, MicroRNA, and protein profiling.

28 September 2017

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Exosome secretion: molecular mechanisms and roles in immune responses

28 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4954869

Selective release of microRNA species from normal and malignant mammary epithelial cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4954869

Complexity of the microRNA repertoire revealed by next-generation sequencing

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4954869

Microfluidic isolation and transcriptome analysis of serum microvesicles

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4954869

Breast cancer subtypes based on ER/PR and Her2 expression: comparison of clinicopathologic features and survival

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4954869

Repertoire of microRNAs in epithelial ovarian cancer as determined by next generation sequencing of small RNA cDNA libraries

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4954869

High levels of exosomes expressing CD63 and caveolin-1 in plasma of melanoma patients

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4954869

Real-time PCR quantification of precursor and mature microRNA.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4954869

Genome-wide microRNA profiling in human fetal nervous tissues by oligonucleotide microarray

28 September 2017

1 reference

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Proteomic analysis of dendritic cell-derived exosomes: a secreted subcellular compartment distinct from apoptotic vesicles

28 September 2017

1 reference

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The impact of disparate isolation methods for extracellular vesicles on downstream RNA profiling

28 September 2017

1 reference

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Reticulocyte maturation and exosome release: transferrin receptor containing exosomes shows multiple plasma membrane functions.

31 May 2018

1 reference

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Functions and therapeutic roles of exosomes in cancer.

31 May 2018

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Mast cell activation contributes to sickle cell pathobiology and pain in mice

21 January 2018

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Expression of tissue levels of matrix metalloproteinases and tissue inhibitors of metalloproteinases in renal cell carcinoma

21 January 2018

1 reference

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MicroRNA-148b is frequently down-regulated in gastric cancer and acts as a tumor suppressor by inhibiting cell proliferation

21 January 2018

1 reference

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Evaluation of quantitative miRNA expression platforms in the microRNA quality control (miRQC) study.

21 January 2018

1 reference

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miRNA in plasma exosome is stable under different storage conditions.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4954869

Comparison of serum exosome isolation methods for microRNA profiling

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4954869

Loss of EpCAM expression in breast cancer derived serum exosomes: role of proteolytic cleavage.

28 November 2018

1 reference

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Epigenetics and microRNAs

28 November 2018

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