Cancer exosomes perform cell-independent microRNA biogenesis and promote tumorigenesis (Q24307717)

Sonia A Melo

1

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Cristina Ivan

Cristina Ivan

12

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August Vidal

August Vidal

6

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George A. Calin

13

George A Calin

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author name string

Hikaru Sugimoto

2

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Joyce T O'Connell

3

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Noritoshi Kato

4

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Alberto Villanueva

5

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Le Qiu

7

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Edward Vitkin

8

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Lev T Perelman

9

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Anthony Lucci

11

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Raghu Kalluri

A genetic defect in exportin-5 traps precursor microRNAs in the nucleus of cancer cells

14

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language of work or name

English

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publication date

10 November 2014

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published in

Cancer Cell

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volume

26

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page(s)

707-21

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issue

5

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cites work

1 reference

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TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencing

19 March 2017

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TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing

19 March 2017

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BIG2, a guanine nucleotide exchange factor for ADP-ribosylation factors: its localization to recycling endosomes and implication in the endosome integrity

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Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs

19 March 2017

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Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells

19 March 2017

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MicroRNA expression profiles classify human cancers

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6 April 2017

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Tumour invasion and metastasis initiated by microRNA-10b in breast cancer

19 March 2017

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Exosomes derived from HIV-1-infected cells contain trans-activation response element RNA

19 March 2017

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Human RISC couples microRNA biogenesis and posttranscriptional gene silencing

19 March 2017

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Exosomes: composition, biogenesis and function

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Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET

7 April 2017

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Functional delivery of viral miRNAs via exosomes

7 April 2017

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Exosomes--vesicular carriers for intercellular communication

7 April 2017

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Shedding microvesicles: artefacts no more

7 April 2017

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MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer

7 April 2017

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7 April 2017

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Aberrant glycosylation as biomarker for cancer: focus on CD43.

7 April 2017

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EGFR modulates microRNA maturation in response to hypoxia through phosphorylation of AGO2.

27 September 2017

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Exosomes in tumor microenvironment influence cancer progression and metastasis

27 September 2017

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An inducible knockout mouse to model the cell-autonomous role of PTEN in initiating endometrial, prostate and thyroid neoplasias

27 September 2017

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BM mesenchymal stromal cell-derived exosomes facilitate multiple myeloma progression.

27 September 2017

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Exosomes from triple-negative breast cancer cells can transfer phenotypic traits representing their cells of origin to secondary cells

27 September 2017

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Neutral sphingomyelinase 2 (nSMase2)-dependent exosomal transfer of angiogenic microRNAs regulate cancer cell metastasis

27 September 2017

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On measuring miRNAs after transient transfection of mimics or antisense inhibitors

27 September 2017

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Exosomes mediate stromal mobilization of autocrine Wnt-PCP signaling in breast cancer cell migration.

27 September 2017

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Oncogenic miRNA-182-5p targets Smad4 and RECK in human bladder cancer

27 September 2017

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Macrophage microvesicles induce macrophage differentiation and miR-223 transfer

27 September 2017

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Argonaute 2 complexes selectively protect the circulating microRNAs in cell-secreted microvesicles

27 September 2017

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The multifaceted exosome: biogenesis, role in normal and aberrant cellular function, and frontiers for pharmacological and biomarker opportunities

27 September 2017

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Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes.

27 September 2017

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Exosomes: secreted vesicles and intercellular communications

27 September 2017

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Intercellular nanovesicle-mediated microRNA transfer: a mechanism of environmental modulation of hepatocellular cancer cell growth

27 September 2017

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Small molecule enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2-mediated microRNA processing

27 September 2017

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Protein targeting to exosomes/microvesicles by plasma membrane anchors

27 September 2017

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Knockdown of miR-21 in human breast cancer cell lines inhibits proliferation, in vitro migration and in vivo tumor growth

27 September 2017

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A MicroRNA targeting dicer for metastasis control

27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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Proteomic profiling of exosomes: current perspectives

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27 September 2017

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RNAi: the nuts and bolts of the RISC machine

27 September 2017

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27 September 2017

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27 September 2017

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Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells.

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29 November 2018

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29 November 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/25446899

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Synthesis of Imidazo[2, 1-a]phthalazines, Potential Inhibitors of p38 MAP Kinase. Prediction of Binding Affinities of Protein Ligands

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PubMed

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inferred from PubMed ID database lookup

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based on heuristic

Identifiers

DOI

10.1016/J.CCELL.2014.09.005

1 reference

411349

411349

1 reference

1 reference

1 reference