In B-CLL, the codon 72 polymorphic variants of p53 are not related to drug resistance and disease prognosis (Q24813088)

4 July 2017

In B-CLL, the codon 72 polymorphic variants of p53 are not related to drug resistance and disease prognosis (English)

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B-cell chronic lymphocytic leukemia

4 July 2017

1 reference

Isrid Sturm

1

1 reference

4 July 2017

Andrew G Bosanquet

2

1 reference

4 July 2017

Michael Hummel

3

1 reference

4 July 2017

Bernd Dörken

4

1 reference

4 July 2017

Peter T Daniel

5

1 reference

4 July 2017

language of work or name

English

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publication date

18 August 2005

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4 July 2017

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4 July 2017

5

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4 July 2017

1

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page(s)

105

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p14ARF induces G2 cell cycle arrest in p53- and p21-deficient cells by down-regulating p34cdc2 kinase activity

4 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1208864

Adenovirus-mediated overexpression of p14(ARF) induces p53 and Bax-independent apoptosis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1208864

A common polymorphism acts as an intragenic modifier of mutant p53 behaviour

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1208864

Loss of p21 disrupts p14 ARF-induced G1 cell cycle arrest but augments p14 ARF-induced apoptosis in human carcinoma cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1208864

Polymorphism p53 codon-72 and invasive cervical cancer: a meta-analysis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1208864

Polymorphism in wild-type p53 modulates response to chemotherapy in vitro and in vivo

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1208864

p53 codon 72 polymorphism and cervical neoplasia: a meta-analysis review

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1208864

Retention of the p53 codon 72 arginine allele is associated with a reduction of disease-free and overall survival in arginine/proline heterozygous breast cancer patients

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1208864

Dynamic expression profile of p21WAF1/CIP1 and Ki-67 predicts survival in rectal carcinoma treated with preoperative radiochemotherapy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1208864

Mutation of p53 and consecutive selective drug resistance in B-CLL occurs as a consequence of prior DNA-damaging chemotherapy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1208864

Combined p53/Bax mutation results in extremely poor prognosis in gastric carcinoma with low microsatellite instability

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1208864

The codon 72 polymorphic variants of p53 have markedly different apoptotic potential

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1208864

Association of p53 codon 72 polymorphism with advanced lung cancer: the Arg allele is preferentially retained in tumours arising in Arg/Pro germline heterozygotes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1208864

Analysis of p53/BAX/p16(ink4a/CDKN2) in esophageal squamous cell carcinoma: high BAX and p16(ink4a/CDKN2) identifies patients with good prognosis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1208864

Analysis of the p53/BAX pathway in colorectal cancer: low BAX is a negative prognostic factor in patients with resected liver metastases

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1208864

Two polymorphic variants of wild-type p53 differ biochemically and biologically

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1208864

Enhanced ex vivo drug sensitivity testing of chronic lymphocytic leukaemia using refined DiSC assay methodology

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1208864

The proline-rich domain of p53 is required for cooperation with anti-neoplastic agents to promote apoptosis of tumor cells

28 September 2017

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-5-105

p53 polymorphic variants at codon 72 exert different effects on cell cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-5-105

p53 codon 72 genotype affects apoptosis by cytosine arabinoside in blood leukocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-5-105

Proline homozygosity in codon 72 of p53 is a factor of susceptibility for thyroid cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-5-105

A TP53 polymorphism is associated with increased risk of colorectal cancer and with reduced levels of TP53 mRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-5-105

Role of a p53 polymorphism in the development of human papillomavirus-associated cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-5-105

Homozygous proline at codon 72 of p53 as a potential risk factor favoring the development of undifferentiated thyroid carcinoma.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1208864

Ex vivo assessment of drug response by differential staining cytotoxicity (DiSC) assay suggests a biological basis for equality of chemotherapy irrespective of age for patients with chronic lymphocytic leukaemia

28 November 2018

1 reference

12 December 2020

p53 Codon 72 polymorphism and urothelial cancer risk

1 reference

12 December 2020

TP53 codon 72 polymorphism in patients with chronic myeloid leukemia

1 reference

12 December 2020

p53 polymorphisms and haplotypes in different ethnic groups

1 reference

12 December 2020

Novel ex vivo analysis of nonclassical, pleiotropic drug resistance and collateral sensitivity induced by therapy provides a rationale for treatment strategies in chronic lymphocytic leukemia

1 reference

12 December 2020

Identifiers

DOI

10.1186/1471-2407-5-105

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Dimensions Publication ID

4 July 2017

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1 reference

4 July 2017

1 reference