Combined p53/Bax mutation results in extremely poor prognosis in gastric carcinoma with low microsatellite instability (Q33186848)

23 July 2017

title

Combined p53/Bax mutation results in extremely poor prognosis in gastric carcinoma with low microsatellite instability (English)

1 reference

23 July 2017

1 reference

1 reference

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28 December 2023

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28 December 2023

author name string

A. Mrózek

1

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28 December 2023

H. Petrowsky

2

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28 December 2023

I. Sturm

3

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J. Kraus

4

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28 December 2023

S. Hermann

5

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S. Hauptmann

6

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M. Lorenz

7

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B. Dörken

8

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P. T. Daniel

9

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28 December 2023

language of work or name

English

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National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12719723

28 December 2023

publication date

1 April 2003

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full work available at URL

23 July 2017

https://www.nature.com/articles/4401193.pdf

file format

Portable Document Format

online access status

open access

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http://www.nature.com/articles/4401193

28 December 2023

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http://www.nature.com/articles/4401193.pdf

28 December 2023

file format

Portable Document Format

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Cell Death & Differentiation

28 December 2023

published in

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23 July 2017

volume

10

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23 July 2017

issue

4

1 reference

23 July 2017

page(s)

461-467

1 reference

https://scigraph.springernature.com/pub.10.1038/sj.cdd.4401193

23 July 2017

exact match

0 references

cites work

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Expression of the bcl-2 gene family in normal and malignant breast tissue: low bax-alpha expression in tumor cells correlates with resistance towards apoptosis

21 January 2018

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Overexpression of the death-promoting gene bax-alpha which is downregulated in breast cancer restores sensitivity to different apoptotic stimuli and reduces tumor growth in SCID mice

21 January 2018

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Bax expression correlates with cellular drug sensitivity to doxorubicin, cyclophosphamide and chlorambucil but not fludarabine, cladribine or corticosteroids in B cell chronic lymphocytic leukemia

21 January 2018

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Adenovirus-mediated overexpression of p14(ARF) induces p53 and Bax-independent apoptosis

21 January 2018

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Ceramide induces mitochondrial activation and apoptosis via a Bax-dependent pathway in human carcinoma cells

21 January 2018

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The apoptosis promoting Bcl-2 homologues Bak and Nbk/Bik overcome drug resistance in Mdr-1-negative and Mdr-1-overexpressing breast cancer cell lines

21 January 2018

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BAX protein expression and clinical outcome in epithelial ovarian cancer

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Analysis of p53/BAX in primary colorectal carcinoma: low BAX protein expression is a negative prognostic factor in UICC stage III tumors

21 January 2018

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Analysis of the p53/BAX pathway in colorectal cancer: low BAX is a negative prognostic factor in patients with resected liver metastases

21 January 2018

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Analysis of p53/BAX/p16(ink4a/CDKN2) in esophageal squamous cell carcinoma: high BAX and p16(ink4a/CDKN2) identifies patients with good prognosis

21 January 2018

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bax, but not bcl-2, influences the prognosis of human pancreatic cancer

21 January 2018

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Relapse in childhood acute lymphoblastic leukemia is associated with a decrease of the Bax/Bcl-2 ratio and loss of spontaneous caspase-3 processing in vivo

21 January 2018

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A novel form of Epstein-Barr virus latency in normal B cells in vivo

21 January 2018

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Keeping killers on a tight leash: transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins

21 January 2018

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Bax expression in benign and malignant thyroid tumours: dysregulation of wild-type P53 is associated with a high Bax and P21 expression in thyroid carcinoma

21 January 2018

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Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype.

21 January 2018

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Impaired BAX protein expression in breast cancer: mutational analysis of the BAX and the p53 gene

21 January 2018

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Gastric cancers of the microsatellite mutator phenotype display characteristic genetic and clinical features

21 January 2018

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Determination of the replication error phenotype in human tumors without the requirement for matching normal DNA by analysis of mononucleotide repeat microsatellites.

21 January 2018

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Molecular nature of colon tumors in hereditary nonpolyposis colon cancer, familial polyposis, and sporadic colon cancer.

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Overexpression of p53 predicts shorter survival in diffuse type gastric cancer.

21 January 2018

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Expression of p53 protein as a prognostic factor in patients with gastric cancer.

21 January 2018

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p53-dependent pathways of apoptosis

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7 January 2021

DNA damage and apoptosis

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7 January 2021

Microsatellite instability at multiple loci in gastric carcinoma: Clinicopathologic implications and prognosis

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7 January 2021

Gastric carcinomas with microsatellite instability: clinical features and mutations to the TGF-beta type II receptor, IGFII receptor, and BAX genes

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Optimising methods for determining RER status in colorectal cancers

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Numerical aberration and point mutation of p53 gene in human gastric intestinal metaplasia and well-differentiated adenocarcinoma: analysis by fluorescence in situ hybridization (FISH) and PCR-SSCP

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7 January 2021

p53 accumulation and mutation are prognostic indicators of poor survival in human gastric carcinoma

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28 December 2023

Identifiers

1 reference

23 July 2017

1 reference