Increased circulating interleukin-12 (IL-12) p40 in pulmonary sarcoidosis (Q24684482)

2

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M Ohmichi

3

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K Kamiguchi

4

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R Takahashi

5

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S Morita-Ichimura

6

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T Ohchi

7

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T Tatsuno

8

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Y Hiraga

9

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S Abe

10

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N Sato

Clinical and Experimental Immunology

11

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language of work or name

English

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publication date

April 2003

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published in

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volume

132

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issue

1

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page(s)

152-7

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cites work

Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12

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Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation

7 April 2017

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Human IL-12 p40 homodimer binds to the IL-12 receptor but does not mediate biologic activity

7 April 2017

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Production of natural killer cell stimulatory factor (interleukin 12) by peripheral blood mononuclear cells

7 April 2017

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Characterization of mouse interleukin-12 p40 homodimer binding to the interleukin-12 receptor subunits

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IL-13 production by NK cells: IL-13-producing NK and T cells are present in vivo in the absence of IFN-gamma.

28 September 2017

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Serum interleukin 12 concentration in juvenile chronic arthritis

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Treatment with homodimeric interleukin-12 (IL-12) p40 protects mice from IL-12-dependent shock but not from tumor necrosis factor alpha-dependent shock

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Serum p55 and p75 tumour necrosis factor receptors as markers of disease activity in juvenile chronic arthritis

28 September 2017

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Lipoteichoic acid preparations of gram-positive bacteria induce interleukin-12 through a CD14-dependent pathway.

28 September 2017

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Interleukin-12: a cytokine produced by antigen-presenting cells with immunoregulatory functions in the generation of T-helper cells type 1 and cytotoxic lymphocytes

28 September 2017

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Interleukin 12 at the site of disease in tuberculosis

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Reduced T helper 1 responses in IL-12 p40 transgenic mice.

28 September 2017

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In vivo production and function of IL-12 p40 homodimers.

30 May 2018

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Induction of IL-12 p40 messenger RNA expression and IL-12 production of macrophages via CD40-CD40 ligand interaction.

30 May 2018

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30 May 2018

Statement on Sarcoidosis

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https://api.crossref.org/works/10.1046%2FJ.1365-2249.2003.02105.X

Mice lacking bioactive IL-12 can generate protective, antigen-specific cellular responses to mycobacterial infection only if the IL-12 p40 subunit is present

21 January 2018

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Sarcoidosis: immunopathogenetic concepts and their clinical application

21 January 2018

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12 December 2020

Effective stimulation for IL-12 p35 mRNA accumulation and bioactive IL-12 production of antigen-presenting cells interacted with Th cells

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12 December 2020

IL-12 and IL-18 are increased and stimulate IFN-gamma production in sarcoid lungs

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12 December 2020

Colorimetry of angiotensin-I converting enzyme activity in serum

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12 December 2020

Expression of interferon-gamma (IFN-gamma), IL-10, IL-12 and transforming growth factor-beta (TGF-beta) mRNA in synovial fluid cells from patients in the early and late phases of rheumatoid arthritis (RA)

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12 December 2020

Enhanced expression of IL-12 associated with Th1 cytokine profiles in active pulmonary sarcoidosis

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12 December 2020