Modeling Development and Disease with Organoids (Q24657457)

Reprogramming cellular identity for regenerative medicine

Europe PubMed Central

title

Modeling Development and Disease with Organoids (English)

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1

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language of work or name

English

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publication date

16 June 2016

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published in

Cell

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volume

165

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page(s)

1586-97

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issue

7

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cites work

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

The intestinal crypt, a prototype stem cell compartment

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7 January 2021

Differentiated Troy+ chief cells act as reserve stem cells to generate all lineages of the stomach epithelium

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https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Organoid cultures derived from patients with advanced prostate cancer

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https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Identification of multipotent luminal progenitor cells in human prostate organoid cultures

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https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Long-term culture of genome-stable bipotent stem cells from adult human liver

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https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Organoid models of human and mouse ductal pancreatic cancer

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https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Prospective derivation of a living organoid biobank of colorectal cancer patients.

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https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Brain-Region-Specific Organoids Using Mini-bioreactors for Modeling ZIKV Exposure

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https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Lgr5-expressing cells are sufficient and necessary for postnatal mammary gland organogenesis

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https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Cellular heterogeneity in the mouse esophagus implicates the presence of a nonquiescent epithelial stem cell population

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Self-organization of polarized cerebellar tissue in 3D culture of human pluripotent stem cells.

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https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Functional Gene Correction for Cystic Fibrosis in Lung Epithelial Cells Generated from Patient iPSCs

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https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Self-formation of layered neural structures in three-dimensional culture of ES cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

The organoid-initiating cells in mouse pancreas and liver are phenotypically and functionally similar

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Self-organized formation of polarized cortical tissues from ESCs and its active manipulation by extrinsic signals

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https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Lgr5(+ve) stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Efficient derivation of purified lung and thyroid progenitors from embryonic stem cells

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https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Self-formation of optic cups and storable stratified neural retina from human ESCs.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Transplantation of expanded fetal intestinal progenitors contributes to colon regeneration after injury

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https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Functional repair of CFTR by CRISPR/Cas9 in intestinal stem cell organoids of cystic fibrosis patients

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Redefining the in vivo origin of metanephric nephron progenitors enables generation of complex kidney structures from pluripotent stem cells

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https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Human pluripotent stem cell culture: considerations for maintenance, expansion, and therapeutics

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https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Regeneration of Thyroid Function by Transplantation of Differentiated Pluripotent Stem Cells

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https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Purification and ex vivo expansion of fully functional salivary gland stem cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Disease Modeling and Gene Therapy of Copper Storage Disease in Canine Hepatic Organoids

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Long-Term In Vitro Expansion of Salivary Gland Stem Cells Driven by Wnt Signals

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Serial cultivation of strains of human epidermal keratinocytes: the formation of keratinizing colonies from single cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

GRAFTING OF BURNS WITH CULTURED EPITHELIUM PREPARED FROM AUTOLOGOUS EPIDERMAL CELLS

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Long-term restoration of damaged corneal surfaces with autologous cultivated corneal epithelium

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Unlimited in vitro expansion of adult bi-potent pancreas progenitors through the Lgr5/R-spondin axis

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Identification of stem cells in small intestine and colon by marker gene Lgr5

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Self-organizing optic-cup morphogenesis in three-dimensional culture

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Generation of functional thyroid from embryonic stem cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Vascularized and functional human liver from an iPSC-derived organ bud transplant.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Cerebral organoids model human brain development and microcephaly

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Alveolar progenitor and stem cells in lung development, renewal and cancer.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

In situ identification of bipotent stem cells in the mammary gland.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Reconstructing lineage hierarchies of the distal lung epithelium using single-cell RNA-seq

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Modelling human development and disease in pluripotent stem-cell-derived gastric organoids

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https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Sequential cancer mutations in cultured human intestinal stem cells.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Cloning and variation of ground state intestinal stem cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Single-cell messenger RNA sequencing reveals rare intestinal cell types

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Directed differentiation of human pluripotent stem cells into mature airway epithelia expressing functional CFTR protein

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Efficient generation of lung and airway epithelial cells from human pluripotent stem cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Directed differentiation of human pluripotent cells to ureteric bud kidney progenitor-like cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Directing human embryonic stem cell differentiation towards a renal lineage generates a self-organizing kidney

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Single luminal epithelial progenitors can generate prostate organoids in culture.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Monitoring and robust induction of nephrogenic intermediate mesoderm from human pluripotent stem cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Plasticity of Hopx(+) type I alveolar cells to regenerate type II cells in the lung.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Generation of functional hippocampal neurons from self-organizing human embryonic stem cell-derived dorsomedial telencephalic tissue

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

The Notch and Wnt pathways regulate stemness and differentiation in human fallopian tube organoids

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Sustained in vitro intestinal epithelial culture within a Wnt-dependent stem cell niche

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Isolation and in vitro expansion of human colonic stem cells.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Functional engraftment of colon epithelium expanded in vitro from a single adult Lgr5⁺ stem cell.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

A functional CFTR assay using primary cystic fibrosis intestinal organoids

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Oncogenic transformation of diverse gastrointestinal tissues in primary organoid culture

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

An in vivo model of human small intestine using pluripotent stem cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Modeling colorectal cancer using CRISPR-Cas9-mediated engineering of human intestinal organoids.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Ductal pancreatic cancer modeling and drug screening using human pluripotent stem cell- and patient-derived tumor organoids

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Niche-independent high-purity cultures of Lgr5+ intestinal stem cells and their progeny

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Ontogeny-recapitulating generation and tissue integration of ES cell-derived Purkinje cells.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Isolation and characterization of intestinal stem cells based on surface marker combinations and colony-formation assay.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

In vitro expansion of human gastric epithelial stem cells and their responses to bacterial infection

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Permanent coverage of large burn wounds with autologous cultured human epithelium

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Limbal Stem-Cell Therapy and Long-Term Corneal Regeneration

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Basal cells as stem cells of the mouse trachea and human airway epithelium

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Single Lgr5- or Lgr6-expressing taste stem/progenitor cells generate taste bud cells ex vivo

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

IL-6/STAT3 promotes regeneration of airway ciliated cells from basal stem cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Human cerebral organoids recapitulate gene expression programs of fetal neocortex development

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Human embryonic stem cells form functional thyroid follicles

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Small intestinal stem cell identity is maintained with functional Paneth cells in heterotopically grafted epithelium onto the colon

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Growing self-organizing mini-guts from a single intestinal stem cell: mechanism and applications

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Organogenesis in a dish: modeling development and disease using organoid technologies

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Stem cell signaling. An integral program for tissue renewal and regeneration: Wnt signaling and stem cell control

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Infectious disease. Life-threatening influenza and impaired interferon amplification in human IRF7 deficiency

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

STEM CELLS. What is an adult stem cell?

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Characterizing responses to CFTR-modulating drugs using rectal organoids derived from subjects with cystic fibrosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Sorting mouse jejunal epithelial cells with CD24 yields a population with characteristics of intestinal stem cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Type 2 alveolar cells are stem cells in adult lung.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Metastatic tumor evolution and organoid modeling implicate TGFBR2 as a cancer driver in diffuse gastric cancer

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Quantification of regenerative potential in primary human mammary epithelial cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

Generating human intestinal tissues from pluripotent stem cells to study development and disease

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

In vitro generation of human pluripotent stem cell derived lung organoids

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2016.05.082

7 January 2021

10.1016/J.CELL.2016.05.082

Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

3238278

3238278

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Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

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