Assignment of the human dihydrofolate reductase gene to the q11----q22 region of chromosome 5 (Q24609496)

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T T Myoda

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P A Moses

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H R Cowell

Molecular and Cellular Biology

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language of work or name

English

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publication date

October 1984

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published in

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volume

4

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issue

10

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page(s)

2010-6

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cites work

Selective linkage disruption in human-Chinese hamster cell hybrids: deletion mapping of the leuS, hexB, emtB, and chr genes on human chromosome 5

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Variable content of double minute chromosomes is not correlated with degree of phenotype instability in methotrexate-resistant human cell lines

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Isolation of Chinese hamster cell mutants deficient in dihydrofolate reductase activity

7 April 2017

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The functional human dihydrofolate reductase gene

7 April 2017

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

7 April 2017

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Gene amplification accompanies low level increases in the activity of dihydrofolate reductase in antifolate-resistant Chinese hamster lung cells containing abnormally banding chromosomes

7 April 2017

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Microcell-mediated cotransfer of genes specifying methotrexate resistance, emetine sensitivity, and chromate sensitivity with Chinese hamster chromosome 2.

27 September 2017

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Multiple forms of human dihydrofolate reductase messenger RNA. Cloning and expression in Escherichia coli of their DNA coding sequence

27 September 2017

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Moderate-level gene amplification in methotrexate-resistant Chinese hamster ovary cells is accompanied by chromosomal translocations at or near the site of the amplified DHFR gene

27 September 2017

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Assignment of the alpha 1-antitrypsin gene and a sequence-related gene to human chromosome 14 by molecular hybridization

27 September 2017

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Human dihydrofolate reductase gene is located in chromosome 5 and is unlinked to the related pseudogenes

27 September 2017

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Quantitative correlation of homogeneously stained regions on chromosome 10 with dihydrofolate reductase enzyme in human cells

27 September 2017

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Amplification of a cloned Chinese hamster dihydrofolate reductase gene after transfer into a dihydrofolate reductase-deficient cell line

27 September 2017

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Organization of a Chinese hamster ovary dihydrofolate reductase gene identified by phenotypic rescue

27 September 2017

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Deletion of the diploid dihydrofolate reductase locus from cultured mammalian cells

27 September 2017

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Structure of the dihydrofolate reductase gene in Chinese hamster ovary cells

27 September 2017

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Overproduction of Dihydrofolate Reductase and Gene Amplification in Methotrexate-Resistant Chinese Hamster Ovary Cells

27 September 2017

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Methotrexate-resistant Chinese hamster ovary cells have amplified a 135-kilobase-pair region that includes the dihydrofolate reductase gene.

27 September 2017

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Molecular cloning of Chinese hamster dihydrofolate reductase-specific cDNA and the identification of multiple dihydrofolate reductase mRNAs in antifolate-resistant Chinese hamster lung fibroblasts

27 September 2017

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Correlation of dihydrofolate reductase elevation with gene amplification in a homogeneously staining chromosomal region in L5178Y cells

27 September 2017

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Phenotypic expression in E. coli of a DNA sequence coding for mouse dihydrofolate reductase

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369017

Amplified dihydrofolate reductase genes in unstably methotrexate-resistant cells are associated with double minute chromosomes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369017

Amplified dihydrofolate reductase genes are localized to a homogeneously staining region of a single chromosome in a methotrexate-resistant Chinese hamster ovary cell line

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369017

In situ detection of mycoplasma contamination in cell cultures by fluorescent Hoechst 33258 stain

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369017

Identification of interspecific translocation chromosomes in human-Chinese hamster hybrid cells

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369017

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369017

A soluble dihydrofolate reductase from human placenta: purification and properties.

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369017

The chromosomes of CHO, an aneuploid Chinese hamster cell line: G-band, C-band, and autoradiographic analyses.

30 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369017

Staining of some specific regions of human chromosomes, particularly the secondary constriction of No. 9.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369017

Polyethylene glycol-induced mammalian cell hybridization: effect of polyethylene glycol molecular weight and concentration

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369017

Proposed banding nomenclature for the Chinese hamster chromosomes (Cricetulus griseus)

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369017

Selective multiplication of dihydrofolate reductase genes in methotrexate-resistant variants of cultured murine cells

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369017

Chromosome stability in CHO cells

30 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369017

Studies on dihydrofolic reductase. I. Purification and properties of dihydrofolic reductase from chicken liver.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369017

Properties of dihydrofolate reductase from a methotrexate-resistant subline of human KB cells and comparison with enzyme from KB parent cells and mouse S180 AT/3000 cells.

19 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369017

Structure and genomic organization of the mouse dihydrofolate reductase gene

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369017

Induction of dihydrofolate reductase activity by SV40 and polyoma virus.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369017

Simultaneous identification of chromatid replication and of human chromosomes in metaphases of man-mouse somatic cell hybrids

28 November 2018

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12 December 2020

Karyotypic heterogeneity in CHO cell lines

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12 December 2020

A simple and efficient procedure for the rapid homogenization of cultured animal cells grown in monolayer

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12 December 2020

Gene amplification in methotrexate-resistant mouse cells. I. DNA rearrangement accompanies dihydrofolate reductase gene amplification in a T-cell lymphoma

1 reference

12 December 2020

Amplification and organization of dihydrofolate reductase genes in a human leukemic cell line, K-562, resistant to methotrexate

1 reference

12 December 2020

Activation of tetrahydrofolate dehydrogenase by certain cations

1 reference

12 December 2020

Differential staining of interspecific chromosomes in somatic cell hybrids by alkaline Giemsa stain

1 reference

12 December 2020