Methotrexate-resistant Chinese hamster ovary cells have amplified a 135-kilobase-pair region that includes the dihydrofolate reductase gene. (Q30450050)

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30 October 2019

title

Methotrexate-resistant Chinese hamster ovary cells have amplified a 135-kilobase-pair region that includes the dihydrofolate reductase gene (English)

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30 October 2019

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W C White

3

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30 October 2019

S M Rothman

series ordinal

4

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30 October 2019

J L Hamlin

series ordinal

5

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30 October 2019

publication date

1 October 1981

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Proceedings of the National Academy of Sciences of the United States of America

30 October 2019

language of work or name

English

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published in

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volume

78

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30 October 2019

issue

10

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30 October 2019

page(s)

6043-6047

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describes a project that uses

30 October 2019

CHOC 400

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cites work

Satellite DNA in large marker chromosomes of methotrexate-resistant mouse cells

1 reference

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Isolation of Chinese hamster cell mutants deficient in dihydrofolate reductase activity

20 June 2018

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

20 June 2018

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A Film Detection Method for Tritium-Labelled Proteins and Nucleic Acids in Polyacrylamide Gels

20 June 2018

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Chapter 3 Detection and Utilization of Poly(A) Sequences in Messenger RNA

20 June 2018

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Nucleotide sequence of the rightward operator of phage lambda

20 June 2018

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An efficient mRNA-dependent translation system from reticulocyte lysates

20 June 2018

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Selective multiplication of dihydrofolate reductase genes in methotrexate-resistant variants of cultured murine cells

20 June 2018

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Chromosome stability in CHO cells

20 June 2018

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Correlation of dihydrofolate reductase elevation with gene amplification in a homogeneously staining chromosomal region in L5178Y cells

20 June 2018

1 reference

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Phenotypic expression in E. coli of a DNA sequence coding for mouse dihydrofolate reductase

20 June 2018

1 reference

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Efficient transfer of large DNA fragments from agarose gels to diazobenzyloxymethyl-paper and rapid hybridization by using dextran sulfate

20 June 2018

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Regulation of dihydrofolate reductase synthesis in an overproducing 3T6 cell line during transition from resting to growing state

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=348973

Amplified dihydrofolate reductase genes are localized to a homogeneously staining region of a single chromosome in a methotrexate-resistant Chinese hamster ovary cell line

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=348973

A novel chromosome abnormality in human neuroblastoma and antifolate-resistant Chinese hamster cell lives in culture

20 June 2018

1 reference

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Antifolate-resistant Chinese hamster cells. Evidence for dihydrofolate reductase gene amplification among independently derived sublines overproducing different dihydrofolate reductases

20 June 2018

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12 December 2020

Replication pattern of a large homogenously staining chromosome region in antifolate-resistant Chinese hamster cell lines

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12 December 2020

Shift in buoyant density of DNA during the synthetic period and its relation to euchromatin and heterochromatin in mammalian cells

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12 December 2020

A rapid banding technique for human chromosomes

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12 December 2020

Chapter 1 Nucleic Acid Hybridization to the DNA of Cytological Preparations

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12 December 2020

Identifiers

DOI

10.1073/PNAS.78.10.6043

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30 October 2019

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24 November 2022

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30 October 2019

PubMed publication ID

6273843

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