TLR signaling pathways (Q24570127)

The Toll gene of Drosophila, required for dorsal-ventral embryonic polarity, appears to encode a transmembrane protein

Europe PubMed Central

title

TLR signaling pathways (English)

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2

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author name string

Kiyoshi Takeda

series ordinal

1

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language of work or name

English

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publication date

February 2004

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published in

Seminars in Immunology

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volume

16

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page(s)

3-9

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issue

1

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cites work

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7 January 2021

Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain

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7 January 2021

The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults

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7 January 2021

IRAK-M is a negative regulator of Toll-like receptor signaling

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7 January 2021

Recognition of CpG DNA is mediated by signaling pathways dependent on the adaptor protein MyD88

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Regulation of interleukin-1- and lipopolysaccharide-induced NF-kappaB activation by alternative splicing of MyD88

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7 January 2021

Distinct and essential roles of transcription factors IRF-3 and IRF-7 in response to viruses for IFN-alpha/beta gene induction

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7 January 2021

Unresponsiveness of MyD88-deficient mice to endotoxin

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7 January 2021

IRF3 mediates a TLR3/TLR4-specific antiviral gene program

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7 January 2021

Functional diversity and regulation of different interleukin-1 receptor-associated kinase (IRAK) family members

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7 January 2021

Tollip, a new component of the IL-1RI pathway, links IRAK to the IL-1 receptor

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7 January 2021

The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5

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7 January 2021

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

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7 January 2021

Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction

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7 January 2021

Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

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7 January 2021

A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

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7 January 2021

The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens.

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7 January 2021

Toll-like receptors: critical proteins linking innate and acquired immunity

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7 January 2021

The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors

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7 January 2021

Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4.

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7 January 2021

Identification of Lps2 as a key transducer of MyD88-independent TIR signalling

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7 January 2021

Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4

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7 January 2021

TIRAP: an adapter molecule in the Toll signaling pathway

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7 January 2021

Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway

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7 January 2021

TLR4, but not TLR2, mediates IFN-beta-induced STAT1alpha/beta-dependent gene expression in macrophages.

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7 January 2021

TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction

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7 January 2021

IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

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7 January 2021

Severe osteopetrosis, defective interleukin-1 signalling and lymph node organogenesis in TRAF6-deficient mice

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7 January 2021

IRAK-4: a novel member of the IRAK family with the properties of an IRAK-kinase

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7 January 2021

A family of human receptors structurally related to Drosophila Toll

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7 January 2021

Negative regulation of toll-like receptor-mediated signaling by Tollip

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7 January 2021

Pellino 1 is required for interleukin-1 (IL-1)-mediated signaling through its interaction with the IL-1 receptor-associated kinase 4 (IRAK4)-IRAK-tumor necrosis factor receptor-associated factor 6 (TRAF6) complex

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7 January 2021

TIRP, a novel Toll/interleukin-1 receptor (TIR) domain-containing adapter protein involved in TIR signaling

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7 January 2021

Immune cell activation by bacterial CpG-DNA through myeloid differentiation marker 88 and tumor necrosis factor receptor-associated factor (TRAF)6.

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7 January 2021

Inhibition of interleukin 1 receptor/Toll-like receptor signaling through the alternatively spliced, short form of MyD88 is due to its failure to recruit IRAK-4

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7 January 2021

Direct triggering of the type I interferon system by virus infection: activation of a transcription factor complex containing IRF-3 and CBP/p300.

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7 January 2021

Deficiency of T2K leads to apoptotic liver degeneration and impaired NF-kappaB-dependent gene transcription

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7 January 2021

Cellular responses to bacterial cell wall components are mediated through MyD88-dependent signaling cascades

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7 January 2021

Differential involvement of IFN-beta in Toll-like receptor-stimulated dendritic cell activation

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7 January 2021

Tumor necrosis factor receptor-associated factors (TRAFs)--a family of adapter proteins that regulates life and death

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7 January 2021

TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling

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7 January 2021

Triggering the interferon antiviral response through an IKK-related pathway

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7 January 2021

Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway

1 reference

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7 January 2021

IRAK: a kinase associated with the interleukin-1 receptor

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https://api.crossref.org/works/10.1016%2FJ.SMIM.2003.10.003

7 January 2021

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

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7 January 2021

Interferon regulatory factor 3 and CREB-binding protein/p300 are subunits of double-stranded RNA-activated transcription factor DRAF1.

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7 January 2021

Cutting edge: preferentially the R-stereoisomer of the mycoplasmal lipopeptide macrophage-activating lipopeptide-2 activates immune cells through a toll-like receptor 2- and MyD88-dependent signaling pathway

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https://api.crossref.org/works/10.1016%2FJ.SMIM.2003.10.003

7 January 2021

IL-1 receptor-associated kinase modulates host responsiveness to endotoxin.

1 reference

https://api.crossref.org/works/10.1016%2FJ.SMIM.2003.10.003

7 January 2021

Lipopolysaccharide stimulates the MyD88-independent pathway and results in activation of IFN-regulatory factor 3 and the expression of a subset of lipopolysaccharide-inducible genes

1 reference

https://api.crossref.org/works/10.1016%2FJ.SMIM.2003.10.003

7 January 2021

https://api.crossref.org/works/10.1016%2FJ.SMIM.2003.10.003

1 reference

7 January 2021

Cutting edge: a novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling

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https://api.crossref.org/works/10.1016%2FJ.SMIM.2003.10.003

7 January 2021

Cutting edge: mouse pellino-2 modulates IL-1 and lipopolysaccharide signaling

1 reference

https://api.crossref.org/works/10.1016%2FJ.SMIM.2003.10.003

7 January 2021