Computational redesign of endonuclease DNA binding and cleavage specificity (Q24569661)

7

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author name string

James J Havranek

2

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Carlos M Duarte

3

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Django Sussman

4

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Raymond J Monnat

5

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Barry L Stoddard

Protein-DNA binding specificity predictions with structural models

6

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language of work or name

English

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publication date

1 June 2006

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published in

Nature

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volume

441

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page(s)

656-9

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issue

7093

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cites work

1 reference

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Therapeutic modulation of endogenous gene function by agents with designed DNA-sequence specificities

24 March 2017

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Mutations altering the cleavage specificity of a homing endonuclease

24 March 2017

1 reference

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Flexible DNA target site recognition by divergent homing endonuclease isoschizomers I-CreI and I-MsoI

24 March 2017

1 reference

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The structure of I-Crel, a group I intron-encoded homing endonuclease

24 March 2017

1 reference

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

24 March 2017

1 reference

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Directed evolution and substrate specificity profile of homing endonuclease I-SceI.

24 March 2017

1 reference

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Engineering of large numbers of highly specific homing endonucleases that induce recombination on novel DNA targets

24 March 2017

1 reference

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Highly efficient endogenous human gene correction using designed zinc-finger nucleases

24 March 2017

1 reference

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Isolation and characterization of new homing endonuclease specificities at individual target site positions

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2999987

Protein structure prediction using Rosetta

24 March 2017

1 reference

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Exploring protein native states and large-scale conformational changes with a modified generalized born model

7 April 2017

1 reference

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Chimeric nucleases stimulate gene targeting in human cells

7 April 2017

1 reference

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Amino acid-base interactions: a three-dimensional analysis of protein-DNA interactions at an atomic level

7 April 2017

1 reference

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Homing endonuclease structure and function

10 May 2017

1 reference

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Rapid evolution of the DNA-binding site in LAGLIDADG homing endonucleases

27 September 2017

1 reference

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Stimulation of homologous recombination through targeted cleavage by chimeric nucleases

27 September 2017

1 reference

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Trading accuracy for speed: A quantitative comparison of search algorithms in protein sequence design

27 September 2017

1 reference

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Structure-based prediction of DNA target sites by regulatory proteins.

27 September 2017

1 reference

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Bayesian statistical analysis of protein side-chain rotamer preferences

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2999987

Sequence-specific recognition of double helical nucleic acids by proteins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2999987

A simple physical model for the prediction and design of protein-DNA interactions.

27 September 2017

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNATURE04818

Efficient in toto targeted recombination in mouse liver by meganuclease-induced double-strand break

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNATURE04818

Molecular biology. Spinning junk into gold

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16738662

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Geometric analysis and comparison of protein-DNA interfaces: why is there no simple code for recognition?

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16738662

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NATURE04818

1 reference

Dimensions Publication ID

1832877

1012756616

0 references

1832877

1 reference

1 reference

1 reference