Transforming growth factor beta2 is a neuronal death-inducing ligand for amyloid-beta precursor protein (Q24338342)

positive regulation of neuron apoptotic process

GOA release 2020-03-11

1 reference

Amyloid beta (A4) precursor protein

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

10

Masaaki Matsuoka

Masaaki

Matsuoka

1 reference

20 October 2023

Yuichi Hashimoto

1

Yuichi

Hashimoto

1 reference

20 October 2023

Tomohiro Chiba

2

Tomohiro

Chiba

1 reference

20 October 2023

Marina Yamada

3

Marina

Yamada

1 reference

20 October 2023

Mikiro Nawa

4

Mikiro

Nawa

1 reference

20 October 2023

Kohsuke Kanekura

5

Kohsuke

Kanekura

1 reference

20 October 2023

Hiroaki Suzuki

6

Hiroaki

Suzuki

1 reference

20 October 2023

Kenzo Terashita

7

Kenzo

Terashita

1 reference

20 October 2023

Sadakazu Aiso

8

Sadakazu

Aiso

1 reference

20 October 2023

Ikuo Nishimoto

9

Ikuo

Molecular and Cellular Biology

Nishimoto

1 reference

20 October 2023

language of work or name

English

0 references

publication date

November 2005

0 references

published in

0 references

volume

25

0 references

page(s)

9304-17

0 references

issue

21

0 references

cites work

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The presenilin 2 mutation (N141I) linked to familial Alzheimer disease (Volga German families) increases the secretion of amyloid beta protein ending at the 42nd (or 43rd) residue

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DNA synthesis and neuronal apoptosis caused by familial Alzheimer disease mutants of the amyloid precursor protein are mediated by the p21 activated kinase PAK3

19 March 2017

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The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

7 April 2017

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Tumor necrosis factor-alpha, interleukin-1beta, and interferon-gamma stimulate gamma-secretase-mediated cleavage of amyloid precursor protein through a JNK-dependent MAPK pathway

7 April 2017

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Mechanisms of TGF-beta-mediated apoptosis

27 September 2017

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27 September 2017

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TGF-beta(1), regulation of alzheimer amyloid precursor protein mRNA expression in a normal human astrocyte cell line: mRNA stabilization

27 September 2017

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Expression of V642 APP mutant causes cellular apoptosis as Alzheimer trait-linked phenotype

27 September 2017

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Alzheimer amyloid protein precursor complexes with brain GTP-binding protein G(o)

27 September 2017

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TGF-beta superfamily members promote survival of midbrain dopaminergic neurons and protect them against MPP+ toxicity

27 September 2017

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Transforming growth factor beta in Alzheimer's disease

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Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production

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Transforming growth factor-beta is a strong and fast acting positive regulator of the level of type-1 plasminogen activator inhibitor mRNA in WI-38 human lung fibroblasts

27 September 2017

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30 May 2018

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30 May 2018

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Differential expression of TGF-beta 1, 2 and 3 isotypes in Alzheimer's disease: a comparative immunohistochemical study with cerebral infarction, aged human and mouse control brains

30 May 2018

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30 May 2018

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30 May 2018

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30 May 2018

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Immunotherapy for Alzheimer's disease

30 May 2018

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Characterization of V642I-AbetaPP-induced cytotoxicity in primary neurons

29 November 2018

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Targeted introduction of V642I mutation in amyloid precursor protein gene causes functional abnormality resembling early stage of Alzheimer's disease in aged mice.

29 November 2018

1 reference

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The cytoplasmic domain of Alzheimer's amyloid-beta protein precursor causes sustained apoptosis signal-regulating kinase 1/c-Jun NH2-terminal kinase-mediated neurotoxic signal via dimerization.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265827

Transforming growth factor-beta 1 potentiates amyloid-beta generation in astrocytes and in transgenic mice.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265827

Secreted Abeta does not mediate neurotoxicity by antibody-stimulated amyloid precursor protein

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265827

Secreted forms of the amyloid-beta precursor protein are ligands for the class A scavenger receptor.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265827

Multiple mechanisms underlie neurotoxicity by different types of Alzheimer's disease mutations of amyloid precursor protein.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265827

Amyloidogenic role of cytokine TGF-beta1 in transgenic mice and in Alzheimer's disease

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265827

G protein-mediated neuronal DNA fragmentation induced by familial Alzheimer's disease-associated mutants of APP.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265827

Regulation of beta-amyloid precursor protein isoform mRNAs by transforming growth factor-beta 1 and interleukin-1 beta in astrocytes.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265827

Differences in beta-amyloid (beta/A4) deposition in human patients with Down's syndrome and sporadic Alzheimer's disease.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1265827

Localization and actions of transforming growth factor-beta s in the embryonic nervous system

29 November 2018

1 reference

12 December 2020

Transforming growth factor beta has neurotrophic actions on sensory neurons in vitro and is synergistic with nerve growth factor

1 reference

12 December 2020

TGF-beta receptors-I and -II immunoexpression in Alzheimer's disease: a comparison with aging and progressive supranuclear palsy

1 reference

12 December 2020

Reduction of endogenous transforming growth factors beta prevents ontogenetic neuron death

1 reference

12 December 2020

10.1128/MCB.25.21.9304-9317.2005

Identifiers

DOI

1 reference

release_6vmwqbzzmrc7fa2qcgdrbxoaz4

1885332

Fatcat ID

0 references

1885332

1 reference

1 reference

1 reference