Binding of cyclic nucleotides to phosphodiesterase 10A and 11A GAF domains does not stimulate catalytic activity (Q24336415)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19689430%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

title

Binding of cyclic nucleotides to phosphodiesterase 10A and 11A GAF domains does not stimulate catalytic activity (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19689430%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

1 reference

Phosphodiesterase 11A

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Phosphodiesterase 10A

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cAMP binding

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author

Jacob Nielsen

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19689430%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

author name string

Karina Matthiesen

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19689430%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

language of work or name

English

0 references

publication date

12 October 2009

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5 February 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19689430%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

volume

423

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5 February 2020

page(s)

401-409

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5 February 2020

issue

3

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Molecular cloning and characterization of a distinct human phosphodiesterase gene family: PDE11A

5 February 2020

cites work

1 reference

Cyclic nucleotide phosphodiesterases: molecular regulation to clinical use

20 April 2017

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Cyclic nucleotide phosphodiesterase (PDE) superfamily: A new target for the development of specific therapeutic agents

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Isolation and characterization of a dual-substrate phosphodiesterase gene family: PDE10A

20 April 2017

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Cloning and characterization of a novel human phosphodiesterase that hydrolyzes both cAMP and cGMP (PDE10A)

20 April 2017

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Immunohistochemical localization of PDE10A in the rat brain

20 April 2017

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Phosphodiesterase 11 (PDE11) regulation of spermatozoa physiology

20 April 2017

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Molecular determinants for cyclic nucleotide binding to the regulatory domains of phosphodiesterase 2A

20 April 2017

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The two GAF domains in phosphodiesterase 2A have distinct roles in dimerization and in cGMP binding

20 April 2017

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PDE5 is converted to an activated state upon cGMP binding to the GAF A domain

20 April 2017

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cAMP is a ligand for the tandem GAF domain of human phosphodiesterase 10 and cGMP for the tandem GAF domain of phosphodiesterase 11

20 April 2017

1 reference

Crystal structure of the GAF-B domain from human phosphodiesterase 10A complexed with its ligand, cAMP

20 April 2017

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Isolation and characterization of two novel phosphodiesterase PDE11A variants showing unique structure and tissue-specific expression

20 April 2017

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Cyclic nucleotide research -- still expanding after half a century

20 April 2017

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PGE(1) stimulation of HEK293 cells generates multiple contiguous domains with different [cAMP]: role of compartmentalized phosphodiesterases

21 January 2018

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Regulation of cAMP and cGMP signaling: new phosphodiesterases and new functions

21 January 2018

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Inhibition of the striatum-enriched phosphodiesterase PDE10A: a novel approach to the treatment of psychosis.

21 January 2018

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The GAF domain: an evolutionary link between diverse phototransducing proteins.

21 January 2018

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GAF domains: two-billion-year-old molecular switches that bind cyclic nucleotides

21 January 2018

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Phosphorylation of isolated human phosphodiesterase-5 regulatory domain induces an apparent conformational change and increases cGMP binding affinity

21 January 2018

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The properties of phosphodiesterase 11A4 GAF domains are regulated by modifications in its N-terminal domain

21 January 2018

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Molecular determinants of cGMP binding to chicken cone photoreceptor phosphodiesterase

21 January 2018

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Modeling and mutational analysis of the GAF domain of the cGMP-binding, cGMP-specific phosphodiesterase, PDE5.

21 January 2018

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Genomic organization of the human phosphodiesterase PDE11A gene. Evolutionary relatedness with other PDEs containing GAF domains

21 January 2018

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Properties and functions of GAF domains in cyclic nucleotide phosphodiesterases and other proteins

21 January 2018

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N-Terminal domain of phosphodiesterase-11A4 (PDE11A4) decreases affinity of the catalytic site for substrates and tadalafil, and is involved in oligomerization.

21 January 2018

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Structural features of the noncatalytic cGMP binding sites of frog photoreceptor phosphodiesterase using cGMP analogs

21 January 2018

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7 January 2021

Structural and functional features in human PDE5A1 regulatory domain that provide for allosteric cGMP binding, dimerization, and regulation

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7 January 2021

Tissue specificity and physiological relevance of various isoforms of adenylyl cyclase

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7 January 2021

Cyclic nucleotide phosphodiesterases: functional implications of multiple isoforms

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7 January 2021