Molecular characterization of human and bovine endothelin converting enzyme (ECE-1) (Q24336315)

protein homodimerization activity

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

M Schmidt

1

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B Kröger

2

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E Jacob

3

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H Seulberger

4

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T Subkowski

5

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R Otter

6

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T Meyer

7

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G Schmalzing

8

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H Hillen

Amino acid sequence of rabbit kidney neutral endopeptidase 24.11 (enkephalinase) deduced from a complementary DNA.

9

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language of work or name

English

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publication date

19 December 1994

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published in

FEBS Letters

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volume

356

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issue

2-3

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page(s)

238-43

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cites work

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7 January 2021

Identification and characterization of endothelin converting activity from EAHY 926 cells: evidence for the physiologically relevant human enzyme

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A novel endothelin ETA receptor antagonist, BQ-485, and its preventive effect on experimental cerebral vasospasm in dogs

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

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7 January 2021

Conversion of big endothelin-1 by membrane-bound metalloendopeptidase in cultured bovine endothelial cells

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7 January 2021

Phosphoramidon, a metalloproteinase inhibitor, suppresses the secretion of endothelin-1 from cultured endothelial cells by inhibiting a big endothelin-1 converting enzyme

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Accumulation of pepstatin in cultured endothelial cells and its effect on endothelial processing

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Exploration of the catalytic site of endopeptidase 24.11 by site-directed mutagenesis. Histidine residues 583 and 587 are essential for catalysis

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7 January 2021

Molecular cloning and amino acid sequence of human enkephalinase (neutral endopeptidase).

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Families of metalloendopeptidases and their relationships

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ECE-1: a membrane-bound metalloprotease that catalyzes the proteolytic activation of big endothelin-1

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7 January 2021

Importance of the C-terminal region of big endothelin-1 for specific conversion by phosphoramidon-sensitive endothelin converting enzyme

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Elevated blood pressure and craniofacial abnormalities in mice deficient in endothelin-1

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Evolutionary families of peptidases

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The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes

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Molecular cloning and primary structure of Kell blood group protein

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Phosphoramidon blocks the pressor activity of porcine big endothelin-1-(1-39) in vivo and conversion of big endothelin-1-(1-39) to endothelin-1-(1-21) in vitro

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The endothelin-converting enzyme from human umbilical vein is a membrane-bound metalloprotease similar to that from bovine aortic endothelial cells

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Endothelin‐converting enzymes

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Topogenic signals in integral membrane proteins

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Asp650 is crucial for catalytic activity of neutral endopeptidase 24-11

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Characterization of a coronary vasoconstrictor produced by cultured endothelial cells

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Attenuation of ischemic acute renal failure by phosphoramidon in rats

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Contribution of endogenous endothelin-1 to the progression of cardiopulmonary alterations in rats with monocrotaline-induced pulmonary hypertension

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