Mutations in LRRK2 increase phosphorylation of peroxiredoxin 3 exacerbating oxidative stress-induced neuronal death (Q24323228)

9

object named as

Zbigniew K Wszolek

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Eng-King Tan

11

object named as

Eng-King Tan

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Matthew J. Farrer

8

object named as

Matt Farrer

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author name string

Dario C Angeles

1

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Bong-Hwa Gan

2

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Luisa Onstead

3

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Yi Zhao

4

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Kah-Leong Lim

5

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Justus Dachsel

6

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Heather Melrose

Localization of LRRK2 to membranous and vesicular structures in mammalian brain

7

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language of work or name

English

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publication date

December 2011

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published in

Human Mutation

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volume

32

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issue

12

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page(s)

1390-7

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cites work

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21582

Roc, a Ras/GTPase domain in complex proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21582

Isoforms of mammalian peroxiredoxin that reduce peroxides in presence of thioredoxin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21582

Parkinson's disease: mechanisms and models

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21582

Roles for the two cysteine residues of AhpC in catalysis of peroxide reduction by alkyl hydroperoxide reductase from Salmonella typhimurium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21582

Advances in our understanding of peroxiredoxin, a multifunctional, mammalian redox protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21582

LRRK2 expression linked to dopamine-innervated areas

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21582

The Parkinson disease causing LRRK2 mutation I2020T is associated with increased kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21582

The Parkinson's disease-associated protein, leucine-rich repeat kinase 2 (LRRK2), is an authentic GTPase that stimulates kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21582

Mitochondrial peroxiredoxin-3 protects hippocampal neurons from excitotoxic injury in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21582

Crystal structure of a multifunctional 2-Cys peroxiredoxin heme-binding protein 23 kDa/proliferation-associated gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21582

Phosphorylation of 4E-BP by LRRK2 affects the maintenance of dopaminergic neurons in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21582

LRRK2 phosphorylates moesin at threonine-558: characterization of how Parkinson's disease mutants affect kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21582

Parkin protects human dopaminergic neuroblastoma cells against dopamine-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21582

Identification of a novel LRRK2 mutation linked to autosomal dominant parkinsonism: evidence of a common founder across European populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21582

Mammalian peroxiredoxin isoforms can reduce hydrogen peroxide generated in response to growth factors and tumor necrosis factor-alpha.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21582

Reversible oxidation and inactivation of the tumor suppressor PTEN in cells stimulated with peptide growth factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21582

Parkinson's disease. First of two parts

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21582

Increased susceptibility of MER5 (peroxiredoxin III) knockout mice to LPS-induced oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21582

Wild-type LRRK2 but not its mutant attenuates stress-induced cell death via ERK pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21582

Microperoxisome distribution in the central nervous system of the rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21582

Anatomical localization of leucine-rich repeat kinase 2 in mouse brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21582

Cellular and molecular mechanisms of Parkinson's disease: neurotoxins, causative genes, and inflammatory cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21582

Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21582

Phosphorylation of ezrin/radixin/moesin proteins by LRRK2 promotes the rearrangement of actin cytoskeleton in neuronal morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21582

PINK1 protects against oxidative stress by phosphorylating mitochondrial chaperone TRAP1

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21582

Peroxiredoxins: a historical overview and speculative preview of novel mechanisms and emerging concepts in cell signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21582

Mitochondria and dopamine: new insights into recessive parkinsonism

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21582

Kinase activity of mutant LRRK2 mediates neuronal toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21582

Pathogenic mutations in Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21582

4-Hydroxy-2-nonenal-modified glyceraldehyde-3-phosphate dehydrogenase is degraded by cathepsin G.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21582

The chaperone activity of heat shock protein 90 is critical for maintaining the stability of leucine-rich repeat kinase 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21582

Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21582

Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21582

Cytosolic peroxiredoxin attenuates the activation of Jnk and p38 but potentiates that of Erk in Hela cells stimulated with tumor necrosis factor-alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21582

inferred from DOI database lookup

7 January 2021

based on heuristic

Intense oxidative DNA damage promoted by L-dopa and its metabolites. Implications for neurodegenerative disease

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21582

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1002/HUMU.21582

1 reference

Consolidated OpenCitations Corpus – April 2017

1574839

1574839

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference