Residual complexes containing SMARCA2 (BRM) underlie the oncogenic drive of SMARCA4 (BRG1) mutation (Q24320038)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24421395%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

title

Residual complexes containing SMARCA2 (BRM) underlie the oncogenic drive of SMARCA4 (BRG1) mutation (English)

1 reference

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5 March 2020

main subject

cell biology

0 references

1 reference

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

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GOA release 2020-03-11

author

Francisca Vazquez

5

1 reference

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5 March 2020

Charles W Roberts

8

1 reference

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5 March 2020

7

William C Hahn

1 reference

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5 March 2020

author name string

Boris G Wilson

1

1 reference

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5 March 2020

Katherine C Helming

2

1 reference

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5 March 2020

Xiaofeng Wang

3

1 reference

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5 March 2020

Youngha Kim

4

1 reference

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5 March 2020

Zainab Jagani

6

1 reference

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5 March 2020

language of work or name

English

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publication date

13 January 2014

1 reference

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Molecular and Cellular Biology

5 March 2020

published in

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5 March 2020

volume

34

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5 March 2020

page(s)

1136-1144

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5 March 2020

issue

6

1 reference

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The spectrum of SWI/SNF mutations, ubiquitous in human cancers

5 March 2020

cites work

1 reference

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Convergent structural alterations define SWItch/Sucrose NonFermentable (SWI/SNF) chromatin remodeler as a central tumor suppressive complex in pancreatic cancer

19 March 2017

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19 March 2017

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19 March 2017

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The human SWI/SNF-B chromatin-remodeling complex is related to yeast rsc and localizes at kinetochores of mitotic chromosomes

19 March 2017

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Rapid and phosphoinositol-dependent binding of the SWI/SNF-like BAF complex to chromatin after T lymphocyte receptor signaling

19 March 2017

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Mitotic inactivation of a human SWI/SNF chromatin remodeling complex

19 March 2017

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Purification and biochemical heterogeneity of the mammalian SWI-SNF complex

19 March 2017

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BRG1 contains a conserved domain of the SWI2/SNF2 family necessary for normal mitotic growth and transcription

19 March 2017

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A human homologue of Saccharomyces cerevisiae SNF2/SWI2 and Drosophila brm genes potentiates transcriptional activation by the glucocorticoid receptor

19 March 2017

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Two human homologues of Saccharomyces cerevisiae SWI2/SNF2 and Drosophila brahma are transcriptional coactivators cooperating with the estrogen receptor and the retinoic acid receptor

19 March 2017

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The genetic landscape of the childhood cancer medulloblastoma

19 March 2017

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Frequent BRG1/SMARCA4-inactivating mutations in human lung cancer cell lines

19 March 2017

1 reference

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Compensation of BRG-1 function by Brm: insight into the role of the core SWI-SNF subunits in retinoblastoma tumor suppressor signaling

19 March 2017

1 reference

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The SWI/SNF chromatin-remodeling complex subunit SNF5 is essential for hepatocyte differentiation

19 March 2017

1 reference

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A Brg1 null mutation in the mouse reveals functional differences among mammalian SWI/SNF complexes

19 March 2017

1 reference

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Altered control of cellular proliferation in the absence of mammalian brahma (SNF2alpha).

19 March 2017

1 reference

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A synthetic lethality-based strategy to treat cancers harboring a genetic deficiency in the chromatin remodeling factor BRG1.

19 March 2017

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Swi/Snf chromatin remodeling/tumor suppressor complex establishes nucleosome occupancy at target promoters

27 September 2017

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BAF complexes facilitate decatenation of DNA by topoisomerase IIα

27 September 2017

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Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy.

27 September 2017

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ATARiS: computational quantification of gene suppression phenotypes from multisample RNAi screens

27 September 2017

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The genetic landscape of mutations in Burkitt lymphoma

27 September 2017

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Functional redundancy of SWI/SNF catalytic subunits in maintaining vascular endothelial cells in the adult heart

27 September 2017

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Heterozygous missense mutations in SMARCA2 cause Nicolaides-Baraitser syndrome

27 September 2017

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TCR-dependent transformation of mature memory phenotype T cells in mice

27 September 2017

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ARID1A, a factor that promotes formation of SWI/SNF-mediated chromatin remodeling, is a tumor suppressor in gynecologic cancers

27 September 2017

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Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer

27 September 2017

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SWI/SNF nucleosome remodellers and cancer.

27 September 2017

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Hijacking the chromatin remodeling machinery: impact of SWI/SNF perturbations in cancer

27 September 2017

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Oncogenesis caused by loss of the SNF5 tumor suppressor is dependent on activity of BRG1, the ATPase of the SWI/SNF chromatin remodeling complex.

27 September 2017

1 reference

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Heterogeneous SWI/SNF chromatin remodeling complexes promote expression of microphthalmia-associated transcription factor target genes in melanoma

27 September 2017

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27 September 2017

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The SWI/SNF complex and cancer

27 September 2017

1 reference

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Frequent loss of Brm expression in gastric cancer correlates with histologic features and differentiation state

27 September 2017

1 reference

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Chromatin remodelling in mammalian differentiation: lessons from ATP-dependent remodellers

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3958034

Inactivation of the Snf5 tumor suppressor stimulates cell cycle progression and cooperates with p53 loss in oncogenic transformation.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3958034

The expression of the SWI/SNF ATPase subunits BRG1 and BRM in normal human tissues.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3958034

Composition and functional specificity of SWI2/SNF2 class chromatin remodeling complexes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3958034

Transcriptional specificity of human SWI/SNF BRG1 and BRM chromatin remodeling complexes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3958034

RB and hbrm cooperate to repress the activation functions of E2F1

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3958034

In-Frame Deletion and Missense Mutations of the C-Terminal Helicase Domain of SMARCA2 in Three Patients with Nicolaides-Baraitser Syndrome.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3958034

Antagonistic roles for BRM and BRG1 SWI/SNF complexes in differentiation

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3958034

A comprehensive molecular study on Coffin-Siris and Nicolaides-Baraitser syndromes identifies a broad molecular and clinical spectrum converging on altered chromatin remodeling.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3958034

Targeted knockout of BRG1 potentiates lung cancer development

29 November 2018

1 reference

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Characterization of mammary tumors from Brg1 heterozygous mice.

29 November 2018

1 reference

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A key role of the hSNF5/INI1 tumour suppressor in the control of the G1-S transition of the cell cycle

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3958034

Concomitant down-regulation of BRM and BRG1 in human tumor cell lines: differential effects on RB-mediated growth arrest vs CD44 expression.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3958034

Highly penetrant, rapid tumorigenesis through conditional inversion of the tumor suppressor gene Snf5

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24421395

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/MCB.01372-13

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24421395%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24421395%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

2 references