Human PinX1 mediates TRF1 accumulation in nucleolus and enhances TRF1 binding to telomeres (Q24318525)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19265708%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

title

Human PinX1 mediates TRF1 accumulation in nucleolus and enhances TRF1 binding to telomeres (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19265708%20AND%20SRC:MED&resulttype=core&format=json

PIN2 (TERF1) interacting telomerase inhibitor 1

22 January 2020

main subject

1 reference

telomeric repeat binding factor 1

GOA release 2020-03-11

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positive regulation of protein localization to nucleolus

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Young Nyun Park

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19265708%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

author name string

Jeong Eun Yoo

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19265708%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Bong-Kyeong Oh

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19265708%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

language of work or name

English

0 references

publication date

3 March 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19265708%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

number of pages

13

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Journal of Molecular Biology

inferred from page(s)

published in

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22 January 2020

volume

388

1 reference

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22 January 2020

issue

5

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22 January 2020

page(s)

928-940

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Nucleolar localization of hTERT protein is associated with telomerase function

22 January 2020

cites work

1 reference

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7 January 2021

Composition and conservation of the telomeric complex

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Sequence requirements for nucleolar localization of human T cell leukemia virus type I pX protein, which regulates viral RNA processing

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Human MCRS2, a cell-cycle-dependent protein, associates with LPTS/PinX1 and reduces the telomere length

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7 January 2021

Characterization of a novel effect of hPinX1 on hTERT nucleolar localization

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7 January 2021

Rat homolog of PinX1 is a nucleolar protein involved in the regulation of telomere length

1 reference

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7 January 2021

The Werner syndrome helicase and exonuclease cooperate to resolve telomeric D loops in a manner regulated by TRF1 and TRF2

1 reference

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7 January 2021

hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization

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7 January 2021

The Pin2/TRF1-interacting protein PinX1 is a potent telomerase inhibitor

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7 January 2021

Repression of the gene encoding the TGF-beta type II receptor is a major target of the EWS-FLI1 oncoprotein

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Control of telomere length by the human telomeric protein TRF1

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7 January 2021

Nucleolar Arf sequesters Mdm2 and activates p53

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7 January 2021

Subnuclear shuttling of human telomerase induced by transformation and DNA damage.

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7 January 2021

Telomerase activation by hTRT in human normal fibroblasts and hepatocellular carcinomas

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Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT

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The SMC5/6 complex maintains telomere length in ALT cancer cells through SUMOylation of telomere-binding proteins

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7 January 2021

MRE11-RAD50-NBS1 and ATM function as co-mediators of TRF1 in telomere length control

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7 January 2021

Telomerase activity is restored in human cells by ectopic expression of hTERT (hEST2), the catalytic subunit of telomerase

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7 January 2021

Identification of the gene for a novel liver-related putative tumor suppressor at a high-frequency loss of heterozygosity region of chromosome 8p23 in human hepatocellular carcinoma

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7 January 2021

Distinct domains in ribosomal protein L5 mediate 5 S rRNA binding and nucleolar localization

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7 January 2021

TANK2, a new TRF1-associated poly(ADP-ribose) polymerase, causes rapid induction of cell death upon overexpression

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7 January 2021

The nucleolar localization domain of the catalytic subunit of human telomerase

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7 January 2021

The yeast homolog of human PinX1 is involved in rRNA and small nucleolar RNA maturation, not in telomere elongation inhibition

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7 January 2021

Nucleolin interacts with telomerase

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7 January 2021

Regulation of telomeric repeat binding factor 1 binding to telomeres by casein kinase 2-mediated phosphorylation

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7 January 2021

Nuclear and nucleolar targeting of human ribosomal protein S6

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7 January 2021

The product of the survival of motor neuron (SMN) gene is a human telomerase-associated protein

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7 January 2021

Telomerase RNA Accumulates in Cajal Bodies in Human Cancer Cells

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7 January 2021

Cell cycle-regulated trafficking of human telomerase to telomeres

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7 January 2021

Cell cycle-dependent recruitment of telomerase RNA and Cajal bodies to human telomeres

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7 January 2021

Association and regulation of the BLM helicase by the telomere proteins TRF1 and TRF2

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7 January 2021

TRF1 is degraded by ubiquitin-mediated proteolysis after release from telomeres

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7 January 2021

Nucleolar protein PinX1p regulates telomerase by sequestering its protein catalytic subunit in an inactive complex lacking telomerase RNA

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7 January 2021

Shelterin: the protein complex that shapes and safeguards human telomeres

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7 January 2021

Ku acts in a unique way at the mammalian telomere to prevent end joining

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7 January 2021

Cross-species difference in telomeric function of tankyrase 1.

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7 January 2021

Telomerase catalytic subunit homologs from fission yeast and human

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7 January 2021

Tankyrase, a poly(ADP-ribose) polymerase at human telomeres

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7 January 2021

Control of human telomere length by TRF1 and TRF2

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7 January 2021

Targeting assay to study the cis functions of human telomeric proteins: evidence for inhibition of telomerase by TRF1 and for activation of telomere degradation by TRF2

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7 January 2021

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Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19265708%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

1 reference