Inhibition of ADAMTS-7 and ADAMTS-12 degradation of cartilage oligomeric matrix protein by alpha-2-macroglobulin (Q24313406)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18485748%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

title

Inhibition of ADAMTS-7 and ADAMTS-12 degradation of cartilage oligomeric matrix protein by alpha-2-macroglobulin (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18485748%20AND%20SRC:MED&resulttype=core&format=json

ADAM metallopeptidase with thrombospondin type 1 motif 12

7 January 2020

main subject

biomedical engineering

0 references

1 reference

ADAM metallopeptidase with thrombospondin type 1 motif 7

1 reference

Alpha-2-macroglobulin

1 reference

cartilage oligomeric matrix protein

1 reference

cellular response to tumor necrosis factor

1 reference

1 reference

9

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7 January 2020

Chuanju Liu

10

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7 January 2020

author name string

Y Luan

1

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7 January 2020

L Kong

2

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7 January 2020

D R Howell

3

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7 January 2020

K Ilalov

4

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7 January 2020

M Fajardo

5

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7 January 2020

X-H Bai

6

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7 January 2020

P E Di Cesare

7

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7 January 2020

M B Goldring

8

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7 January 2020

language of work or name

English

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publication date

15 May 2008

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Osteoarthritis and Cartilage

7 January 2020

published in

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7 January 2020

volume

16

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7 January 2020

page(s)

1413-1420

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7 January 2020

issue

11

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The ADAMTS12 metalloproteinase exhibits anti-tumorigenic properties through modulation of the Ras-dependent ERK signalling pathway

7 January 2020

cites work

1 reference

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Interaction of cartilage oligomeric matrix protein/thrombospondin 5 with aggrecan

19 March 2017

1 reference

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ADAMTS-12 associates with and degrades cartilage oligomeric matrix protein

19 March 2017

1 reference

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Interactions between the cartilage oligomeric matrix protein and matrilins. Implications for matrix assembly and the pathogenesis of chondrodysplasias

19 March 2017

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Matrix-matrix interaction of cartilage oligomeric matrix protein and fibronectin

19 March 2017

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Structure of von Willebrand factor-cleaving protease (ADAMTS13), a metalloprotease involved in thrombotic thrombocytopenic purpura

19 March 2017

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Procollagen II amino propeptide processing by ADAMTS-3. Insights on dermatosparaxis

19 March 2017

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ADAM-TS5, ADAM-TS6, and ADAM-TS7, novel members of a new family of zinc metalloproteases. General features and genomic distribution of the ADAM-TS family

19 March 2017

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Cloning and characterization of ADAMTS11, an aggrecanase from the ADAMTS family

19 March 2017

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Human Ehlers-Danlos syndrome type VII C and bovine dermatosparaxis are caused by mutations in the procollagen I N-proteinase gene

19 March 2017

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Purification and cloning of aggrecanase-1: a member of the ADAMTS family of proteins

19 March 2017

1 reference

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Cartilage and bone metabolism in rheumatoid arthritis. Differences between rapid and slow progression of disease identified by serum markers of cartilage metabolism

19 March 2017

1 reference

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ADAMTS-8 exhibits aggrecanase activity and is expressed in human articular cartilage

19 March 2017

1 reference

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ADAMTS7B, the full-length product of the ADAMTS7 gene, is a chondroitin sulfate proteoglycan containing a mucin domain

19 March 2017

1 reference

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A disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motifs: the ADAMTS family

19 March 2017

1 reference

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Transforming growth factor-beta induces secretion of activated ADAMTS-2. A procollagen III N-proteinase

19 March 2017

1 reference

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Cloning and characterization of ADAMTS-14, a novel ADAMTS displaying high homology with ADAMTS-2 and ADAMTS-3

19 March 2017

1 reference

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Versican V1 proteolysis in human aorta in vivo occurs at the Glu441-Ala442 bond, a site that is cleaved by recombinant ADAMTS-1 and ADAMTS-4

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2574789

Brevican is degraded by matrix metalloproteinases and aggrecanase-1 (ADAMTS4) at different sites

19 March 2017

1 reference

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ADAMTS-1 is an active metalloproteinase associated with the extracellular matrix

19 March 2017

1 reference

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Cartilage oligomeric matrix protein shows high affinity zinc-dependent interaction with triple helical collagen

19 March 2017

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The ADAMTS metalloproteinases

19 March 2017

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Radiological assessment of osteo-arthrosis

7 April 2017

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ADAMTS-7: a metalloproteinase that directly binds to and degrades cartilage oligomeric matrix protein

7 April 2017

1 reference

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ADAMTS5 is the major aggrecanase in mouse cartilage in vivo and in vitro

27 September 2017

1 reference

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Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis

27 September 2017

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von Willebrand factor-cleaving protease (ADAMTS-13) activity determination in the diagnosis of thrombotic microangiopathies: the Swiss experience

27 September 2017

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Alpha2-macroglobulin is a novel substrate for ADAMTS-4 and ADAMTS-5 and represents an endogenous inhibitor of these enzymes

27 September 2017

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Altered proteolytic activities of ADAMTS-4 expressed by C-terminal processing

27 September 2017

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ADAMTS-13 cysteine-rich/spacer domains are functionally essential for von Willebrand factor cleavage

27 September 2017

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Expression of ADAMTS metalloproteinases in the retinal pigment epithelium derived cell line ARPE-19: transcriptional regulation by TNFalpha.

27 September 2017

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Matrix metalloproteinases in neuroinflammation

27 September 2017

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Inhibition of ADAM-TS4 and ADAM-TS5 prevents aggrecan degradation in osteoarthritic cartilage

27 September 2017

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Leech thrombin inhibitors

27 September 2017

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Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpura

27 September 2017

1 reference

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Expression and activity of ADAMTS-5 in synovium

27 September 2017

1 reference

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Expression of cartilage oligomeric matrix protein (COMP) by embryonic and adult osteoblasts

27 September 2017

1 reference

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cDNA cloning and expression of bovine procollagen I N-proteinase: a new member of the superfamily of zinc-metalloproteinases with binding sites for cells and other matrix components.

27 September 2017

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The proteinase-binding reaction of alpha 2M.

27 September 2017

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Alpha-macroglobulins: structure, shape, and mechanism of proteinase complex formation

27 September 2017

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Alpha 2-macroglobulin, a multifunctional binding protein with targeting characteristics

27 September 2017

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The interaction of alpha 2-macroglobulin with proteinases. Characteristics and specificity of the reaction, and a hypothesis concerning its molecular mechanism

27 September 2017

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Differential expression of plasminogen activator inhibitor-1, tumor necrosis factor-alpha, TNF-alpha converting enzyme and ADAMTS family members in murine fat territories

27 September 2017

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Increased degradation and altered tissue distribution of cartilage oligomeric matrix protein in human rheumatoid and osteoarthritic cartilage.

30 May 2018

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Interaction of human rheumatoid synovial collagenase (matrix metalloproteinase 1) and stromelysin (matrix metalloproteinase 3) with human alpha 2-macroglobulin and chicken ovostatin. Binding kinetics and identification of matrix metalloproteinase cl

30 May 2018

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Proteoglycans from the swarm rat chondrosarcoma. Structure of the aggregates extracted with associative and dissociative solvents as revealed by electron microscopy

30 May 2018

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COMP (cartilage oligomeric matrix protein) is structurally related to the thrombospondins

30 May 2018

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Role of aggrecanase 1 in Lyme arthritis.

30 May 2018

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The cleavage of biglycan by aggrecanases.

29 November 2018

1 reference

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ADAMTS-1 and -4 are up-regulated following transient middle cerebral artery occlusion in the rat and their expression is modulated by TNF in cultured astrocytes.

29 November 2018

1 reference

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ADAMTS-9 is synergistically induced by interleukin-1beta and tumor necrosis factor alpha in OUMS-27 chondrosarcoma cells and in human chondrocytes.

29 November 2018

1 reference

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Inhibition of interleukin-1beta-stimulated production of matrix metalloproteinases by hyaluronan via CD44 in human articular cartilage

29 November 2018

1 reference

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IL-1 beta induces COX2, MMP-1, -3 and -13, ADAMTS-4, IL-1 beta and IL-6 in human tendon cells

29 November 2018

1 reference

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Mature Full-thickness Articular Cartilage Explants Attached to Bone are Physiologically Stable over Long-term Culture in Serum-free Media

29 November 2018

1 reference

12 December 2020

Cleavage of cartilage oligomeric matrix protein (thrombospondin-5) by matrix metalloproteinases and a disintegrin and metalloproteinase with thrombospondin motifs

1 reference

12 December 2020

Cartilage matrix proteins. An acidic oligomeric protein (COMP) detected only in cartilage

1 reference

12 December 2020

Cartilage oligomeric matrix protein: a novel marker of cartilage turnover detectable in synovial fluid and blood

1 reference

12 December 2020

Cartilage oligomeric matrix protein (COMP) is an abundant component of tendon

1 reference

12 December 2020

Small fragments of cartilage oligomeric matrix protein in synovial fluid and serum as markers for cartilage degradation

1 reference

12 December 2020

Localization and expression of cartilage oligomeric matrix protein by human rheumatoid and osteoarthritic synovium and cartilage

1 reference

12 December 2020

Lectin-like oxidized low-density lipoprotein receptor 1 mediates matrix metalloproteinase 3 synthesis enhanced by oxidized low-density lipoprotein in rheumatoid arthritis cartilage

1 reference

12 December 2020

Distribution of aggrecanase (ADAMts 4/5) cleavage products in normal and osteoarthritic human articular cartilage: the influence of age, topography and zone of tissue

1 reference

12 December 2020

Loading-induced changes in synovial fluid affect cartilage metabolism

1 reference

12 December 2020

10.1016/J.JOCA.2008.03.017

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DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18485748%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18485748%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1 reference