Alpha-2-macroglobulin (Q22680187)

Alpha-macroglobulin, receptor-binding domain superfamily

1 reference

Immunoglobulin E-set

1 reference

Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid

1 reference

Alpha-2-macroglobulin, protein family

1 reference

Alpha-macroglobulin, receptor-binding domain, protein family

1 reference

Macroglobulin domain, protein family

1 reference

Alpha-2-macroglobulin, bait region domain, protein family

1 reference

Alpha-macroglobulin, TED domain, protein family

1 reference

Alpha-2-macroglobulin, conserved site, protein family

1 reference

TonB box, conserved site, protein family

1 reference

peptidase inhibitor activity

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01023

Involvement of alpha-2-macroglobulin receptor in clearance of interleukin 8-alpha-2-macroglobulin complexes by human alveolar macrophages

interleukin-8 binding

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01023

Human alpha 2-macroglobulin is an osteogenic growth peptide-binding protein

IPI

growth factor binding

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01023

calcium-dependent protein binding

1 reference

9 May 2019

Identification and characterization of the acidic pH binding sites for growth regulatory ligands of low density lipoprotein receptor-related protein-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01023

1 reference

8 April 2019

Inhibition of ADAMTS-7 and ADAMTS-12 degradation of cartilage oligomeric matrix protein by alpha-2-macroglobulin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01023

3 references

9 May 2019

Complex formation between human kallikrein 13 and serum protease inhibitors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01023

9 May 2019

Mesotrypsin: a new inhibitor-resistant protease from a zymogen in human pancreatic tissue and fluid

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01023

9 May 2019

Identification and characterization of the acidic pH binding sites for growth regulatory ligands of low density lipoprotein receptor-related protein-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01023

1 reference

9 May 2019

Interaction of lecithin:cholesterol acyltransferase (LCAT).alpha 2-macroglobulin complex with low density lipoprotein receptor-related protein (LRP). Evidence for an alpha 2-macroglobulin/LRP receptor-mediated system participating in LCAT clearance

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01023

tumor necrosis factor binding

IPI

1 reference

9 May 2019

A modified human alpha 2-macroglobulin derivative that binds tumor necrosis factor-alpha and interleukin-1 beta with high affinity in vitro and reverses lipopolysaccharide toxicity in vivo in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01023

endopeptidase inhibitor activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01023

A modified human alpha 2-macroglobulin derivative that binds tumor necrosis factor-alpha and interleukin-1 beta with high affinity in vitro and reverses lipopolysaccharide toxicity in vivo in mice

interleukin-1 binding

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01023

signaling receptor binding

1 reference

9 May 2019

Identification and characterization of the acidic pH binding sites for growth regulatory ligands of low density lipoprotein receptor-related protein-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01023

GTPase activator activity

IMP

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01023&geneProductId=UniProtKB:P01023

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01023

1 reference

26 September 2017

Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01023&geneProductId=UniProtKB:P01023

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01023

9 May 2019

The human plasma proteome: a nonredundant list developed by combination of four separate sources

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01023

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01023

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01023

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine

extracellular exosome

4 references

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01023&geneProductId=UniProtKB:P01023

26 September 2017

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01023&geneProductId=UniProtKB:P01023

26 September 2017

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01023&geneProductId=UniProtKB:P01023

26 September 2017

Protein profile of exosomes from trabecular meshwork cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01023&geneProductId=UniProtKB:P01023

platelet alpha granule lumen

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01023

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01023

collagen-containing extracellular matrix

3 references

9 May 2019

Comprehensive proteomic characterization of stem cell-derived extracellular matrices.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01023

9 May 2019

Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01023

9 May 2019

Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01023

Protein profile of exosomes from trabecular meshwork cells

HDA

extracellular exosome

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01023

9 May 2019

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01023

9 May 2019

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01023

1 reference

9 May 2019

Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01023

blood coagulation, intrinsic pathway

HDA

biological process

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01023

negative regulation of peptidase activity

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01023

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01023

platelet degranulation

1 reference

9 May 2019

extracellular matrix disassembly

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01023

stem cell differentiation

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01023

negative regulation of complement activation, lectin pathway

1 reference

9 May 2019

Natural substrates and inhibitors of mannan-binding lectin-associated serine protease-1 and -2: a study on recombinant catalytic fragments

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01023

regulation of small GTPase mediated signal transduction

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01023

positive regulation of GTPase activity

1 reference

1 January 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01023&geneProductId=UniProtKB:P01023

negative regulation of endopeptidase activity

1 reference

9 May 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01023

Alpha-macroglobulin, TED domain

has part(s)

1 reference

Alpha-2-macroglobulin

1 reference

TonB box, conserved site

1 reference

Alpha-2-macroglobulin, bait region domain

1 reference

Macroglobulin domain

1 reference

Alpha-2-macroglobulin, conserved site

1 reference

Alpha-macroglobulin, receptor-binding

1 reference