Nogo-B receptor stabilizes Niemann-Pick type C2 protein and regulates intracellular cholesterol trafficking (Q24311592)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19723497%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

title

Nogo-B receptor stabilizes Niemann-Pick type C2 protein and regulates intracellular cholesterol trafficking (English)

1 reference

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NPC intracellular cholesterol transporter 2

6 February 2020

main subject

cell biology

0 references

1 reference

Cathepsin D

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NUS1 dehydrodolichyl diphosphate synthase subunit

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Calnexin

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regulation of intracellular cholesterol transport

1 reference

NUS1 dehydrodolichyl diphosphate synthase subunit

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author

Alberto Davalos

5

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6 February 2020

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William C Sessa

1 reference

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6 February 2020

author name string

Kenneth D Harrison

1

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6 February 2020

Robert Qing Miao

2

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6 February 2020

Carlos Fernandez-Hernándo

3

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6 February 2020

Yajaira Suárez

4

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6 February 2020

language of work or name

English

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publication date

1 September 2009

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6 February 2020

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6 February 2020

volume

10

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6 February 2020

page(s)

208-218

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6 February 2020

issue

3

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NPC2 facilitates bidirectional transfer of cholesterol between NPC1 and lipid bilayers, a step in cholesterol egress from lysosomes

6 February 2020

cites work

1 reference

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Niemann-Pick C1 protects against atherosclerosis in mice via regulation of macrophage intracellular cholesterol trafficking

19 March 2017

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NPC2, the protein deficient in Niemann-Pick C2 disease, consists of multiple glycoforms that bind a variety of sterols

19 March 2017

1 reference

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In vivo interaction between the human dehydrodolichyl diphosphate synthase and the Niemann-Pick C2 protein revealed by a yeast two-hybrid system

19 March 2017

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A new role for Nogo as a regulator of vascular remodeling

19 March 2017

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NPC1 and NPC2 Regulate Cellular Cholesterol Homeostasis through Generation of Low Density Lipoprotein Cholesterol-derived Oxysterols

19 March 2017

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Structure of a cholesterol-binding protein deficient in Niemann-Pick type C2 disease

19 March 2017

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Identification of HE1 as the second gene of Niemann-Pick C disease

19 March 2017

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Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis

19 March 2017

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Improved prediction of signal peptides: SignalP 3.0

19 March 2017

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The subcellular localization of the Niemann-Pick Type C proteins depends on the adaptor complex AP-3.

19 March 2017

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Human CD36 is a high affinity receptor for the native lipoproteins HDL, LDL, and VLDL

19 March 2017

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Genetic evidence for nonredundant functional cooperativity between NPC1 and NPC2 in lipid transport

19 March 2017

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Identification and characterization of a cDNA encoding a long-chain cis-isoprenyltranferase involved in dolichyl monophosphate biosynthesis in the ER of brain cells

19 March 2017

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Protein sensors for membrane sterols

19 March 2017

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A receptor-mediated pathway for cholesterol homeostasis

7 April 2017

1 reference

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Regulation of protein O-glycosylation by the endoplasmic reticulum-localized molecular chaperone Cosmc

7 April 2017

1 reference

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Cellular cholesterol trafficking and compartmentalization

27 September 2017

1 reference

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Purified NPC1 protein: II. Localization of sterol binding to a 240-amino acid soluble luminal loop

27 September 2017

1 reference

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Identification of Golgi-localized acyl transferases that palmitoylate and regulate endothelial nitric oxide synthase

27 September 2017

1 reference

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Identification of a receptor necessary for Nogo-B stimulated chemotaxis and morphogenesis of endothelial cells

27 September 2017

1 reference

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Intracellular sterol transport and distribution.

27 September 2017

1 reference

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Automated microscopy screening for compounds that partially revert cholesterol accumulation in Niemann-Pick C cells

27 September 2017

1 reference

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Niemann-Pick type C disease: importance of N-glycosylation sites for function and cellular location of the NPC2 protein

27 September 2017

1 reference

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The NPC1 protein: structure implies function.

27 September 2017

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Niemann-Pick C research from mouse to gene

27 September 2017

1 reference

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The integrity of a cholesterol-binding pocket in Niemann-Pick C2 protein is necessary to control lysosome cholesterol levels.

27 September 2017

1 reference

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The intracellular transport of low density lipoprotein-derived cholesterol is defective in Niemann-Pick type C fibroblasts

27 September 2017

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Hairpin orientation of sterol regulatory element-binding protein-2 in cell membranes as determined by protease protection

27 September 2017

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Switch-like control of SREBP-2 transport triggered by small changes in ER cholesterol: a delicate balance

27 September 2017

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Inhibition of cholesterol biosynthesis by Delta22-unsaturated phytosterols via competitive inhibition of sterol Delta24-reductase in mammalian cells

30 May 2018

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Murine model of Niemann-Pick C disease: mutation in a cholesterol homeostasis gene.

30 May 2018

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Niemann-Pick type C1 I1061T mutant encodes a functional protein that is selected for endoplasmic reticulum-associated degradation due to protein misfolding

30 May 2018

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Purified NPC1 protein. I. Binding of cholesterol and oxysterols to a 1278-amino acid membrane protein.

29 November 2018

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Development of an assay for the intermembrane transfer of cholesterol by Niemann-Pick C2 protein

29 November 2018

1 reference

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Mechanism of cholesterol transfer from the Niemann-Pick type C2 protein to model membranes supports a role in lysosomal cholesterol transport.

29 November 2018

1 reference

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Differential trafficking of the Niemann-Pick C1 and 2 proteins highlights distinct roles in late endocytic lipid trafficking.

29 November 2018

1 reference

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Fluorescent labeling of lipoproteins

29 November 2018

1 reference

12 December 2020

Type C Niemann-Pick disease. Abnormal metabolism of low density lipoprotein in homozygous and heterozygous fibroblasts

1 reference

12 December 2020

Low density lipoprotein (LDL)-mediated suppression of cholesterol synthesis and LDL uptake is defective in Niemann-Pick type C fibroblasts

1 reference

12 December 2020

Biosynthesis and palmitoylation of endothelial nitric oxide synthase: mutagenesis of palmitoylation sites, cysteines-15 and/or -26, argues against depalmitoylation-induced translocation of the enzyme

1 reference

12 December 2020

10.1016/J.CMET.2009.07.003

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DOI

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6 February 2020

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6 February 2020

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