EphA2 is an essential mediator of UV radiation-induced apoptosis (Q24311103)

GOA release 2020-03-11

author name string

Guoqi Zhang

1

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Ching-Ni Njauw

2

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Jong Min Park

3

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Chie Naruse

4

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Masahide Asano

5

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Hensin Tsao

A novel mechanism for p53 to regulate its target gene ECK in signaling apoptosis

6

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language of work or name

English

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publication date

15 March 2008

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published in

Cancer Research

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volume

68

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issue

6

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page(s)

1691-6

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cites work

1 reference

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Overexpression and functional alterations of the EphA2 tyrosine kinase in cancer

19 March 2017

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Involvement of EphA2 in the formation of the tail notochord via interaction with ephrinA1

19 March 2017

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Ultraviolet radiation triggers apoptosis of fibroblasts and skin keratinocytes mainly via the BH3-only protein Noxa.

19 March 2017

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Expression profiling of UVB response in melanocytes identifies a set of p53-target genes

27 September 2017

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Over-expression of Eph and ephrin genes in advanced ovarian cancer: ephrin gene expression correlates with shortened survival

27 September 2017

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EphA2 as a target for ovarian cancer therapy

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A conditional feedback loop regulates Ras activity through EphA2.

27 September 2017

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The clinical significance of EphA2 and Ephrin A-1 in epithelial ovarian carcinomas

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Expression of EphA2 is prognostic of disease-free interval and overall survival in surgically treated patients with renal cell carcinoma

27 September 2017

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EphA2: expression in the renal medulla and regulation by hypertonicity and urea stress in vitro and in vivo

27 September 2017

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Role of reactive oxygen species in skin carcinogenesis

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EphA2 overexpression correlates with poor prognosis in esophageal squamous cell carcinoma

27 September 2017

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Mechanisms of apoptosis by c-Myc

27 September 2017

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A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma

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Expression profile of Eph receptors and ephrin ligands in human skin and downregulation of EphA1 in nonmelanoma skin cancer

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Disruption of EphA2 receptor tyrosine kinase leads to increased susceptibility to carcinogenesis in mouse skin

30 May 2018

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VE-cadherin regulates EphA2 in aggressive melanoma cells through a novel signaling pathway: implications for vasculogenic mimicry

30 May 2018

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Ephrins and their receptors: a repulsive topic?

30 May 2018

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Upregulation of EphA2 during in vivo and in vitro renal ischemia-reperfusion injury: role of Src kinases.

30 May 2018

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Soluble Eph A receptors inhibit tumor angiogenesis and progression in vivo.

29 November 2018

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Receptor tyrosine kinase EphA2 is regulated by p53-family proteins and induces apoptosis

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469360

The ephrin-A1 ligand and its receptor, EphA2, are expressed during tumor neovascularization

29 November 2018

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29 November 2018

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https://pubmed.ncbi.nlm.nih.gov/18339848