Cathepsin H is an additional convertase of pro-granzyme B (Q24309194)

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1 February 2020

title

Cathepsin H is an additional convertase of pro-granzyme B (English)

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1 February 2020

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zymogen activation

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Cathepsin C

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Cathepsin H

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author

Michael E D'Angelo

1

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1 February 2020

Phillip I. Bird

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20435891%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

Thomas Reinheckel

4

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1 February 2020

Joseph A. Trapani

5

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1 February 2020

author name string

Christoph Peters

3

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1 February 2020

Vivien R Sutton

6

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1 February 2020

language of work or name

English

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publication date

30 April 2010

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Journal of Biological Chemistry

1 February 2020

published in

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1 February 2020

volume

285

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1 February 2020

page(s)

20514-20519

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1 February 2020

issue

27

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Granzyme H destroys the function of critical adenoviral proteins required for viral DNA replication and granzyme B inhibition

1 February 2020

cites work

1 reference

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The major human and mouse granzymes are structurally and functionally divergent

19 March 2017

1 reference

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Catalytic properties and inhibition of proline-specific dipeptidyl peptidases II, IV and VII

19 March 2017

1 reference

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Active and zymogen forms of granzyme B are constitutively released from cytotoxic lymphocytes in the absence of target cell engagement.

19 March 2017

1 reference

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Residual active granzyme B in cathepsin C-null lymphocytes is sufficient for perforin-dependent target cell apoptosis

27 September 2017

1 reference

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Extracellular matrix remodeling by human granzyme B via cleavage of vitronectin, fibronectin, and laminin.

27 September 2017

1 reference

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Purification of natural killer cell cytotoxic granules for assaying target cell apoptosis.

27 September 2017

1 reference

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Expression and purification of recombinant human granzyme B from Pichia pastoris

27 September 2017

1 reference

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Dipeptidyl peptidase I is required for the processing and activation of granzymes A and B in vivo

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898313

In vitro- and ex vivo-derived cytolytic leukocytes from granzyme A x B double knockout mice are defective in granule-mediated apoptosis but not lysis of target cells

27 September 2017

1 reference

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The lytic granules of natural killer cells are dual-function organelles combining secretory and pre-lysosomal compartments

27 September 2017

1 reference

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Expression of recombinant human granzyme B. A processing and activation role for dipeptidyl peptidase I.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898313

Kinetic investigation of human dipeptidyl peptidase II (DPPII)-mediated hydrolysis of dipeptide derivatives and its identification as quiescent cell proline dipeptidase (QPP)/dipeptidyl peptidase 7 (DPP7).

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898313

Novel serine proteases encoded by two cytotoxic T lymphocyte-specific genes

30 May 2018

1 reference

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An unusual specificity in the activation of neutrophil serine proteinase zymogens

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898313

A natural killer cell granule protein that induces DNA fragmentation and apoptosis

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898313

Granzymes A and B are targeted to the lytic granules of lymphocytes by the mannose-6-phosphate receptor

30 May 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.094573

Papillon-Lefèvre syndrome: correlating the molecular, cellular, and clinical consequences of cathepsin C/dipeptidyl peptidase I deficiency in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.094573

Loss-of-function mutations in cathepsin C in two families with Papillon-Lefèvre syndrome are associated with deficiency of serine proteinases in PMNs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.094573

Importance of the P4' residue in human granzyme B inhibitors and substrates revealed by scanning mutagenesis of the proteinase inhibitor 9 reactive center loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.094573

Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.094573

Antihemostatic Activity of Human Granzyme B Mediated by Cleavage of von Willebrand Factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.094573

Bcl-2 prevents apoptosis induced by perforin and granzyme B, but not that mediated by whole cytotoxic lymphocytes

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898313

Activation of recombinant murine cytotoxic cell proteinase-1 requires deletion of an amino-terminal dipeptide

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20435891

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Reorientation and fusion of cytotoxic T lymphocyte granules after interaction with target cells as determined by high resolution cinemicrography

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20435891

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Inhibition of the activation of multiple serine proteases with a cathepsin C inhibitor requires sustained exposure to prevent pro-enzyme processing

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20435891

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M109.094573

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20435891%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20435891%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

1 reference