The ubiquitin-specific protease USP28 is required for MYC stability (Q24308568)

Ubiquitin specific peptidase 28

GOA release 2020-03-11

1 reference

thiol-dependent deubiquitinase

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Stephen Elledge

8

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Martin Eilers

object named as

Martin Eilers

9

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René Bernards

object named as

Rene Bernards

6

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Roderick L Beijersbergen

object named as

Roderick Beijersbergen

5

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author name string

Nikita Popov

1

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Michael Wanzel

2

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Mandy Madiredjo

3

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Dong Zhang

4

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Roland Moll

Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7

7

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language of work or name

English

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publication date

July 2007

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published in

Nature Cell Biology

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volume

9

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issue

7

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page(s)

765-74

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cites work

1 reference

A genomic and functional inventory of deubiquitinating enzymes

20 April 2017

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A large-scale RNAi screen in human cells identifies new components of the p53 pathway

20 April 2017

1 reference

A role for the deubiquitinating enzyme USP28 in control of the DNA-damage response

20 April 2017

1 reference

Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase

20 April 2017

1 reference

Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line

20 April 2017

1 reference

Control of the SCF(Skp2-Cks1) ubiquitin ligase by the APC/C(Cdh1) ubiquitin ligase

20 April 2017

1 reference

Multisite phosphorylation by Cdk2 and GSK3 controls cyclin E degradation

20 April 2017

1 reference

The Rsp5 ubiquitin ligase is coupled to and antagonized by the Ubp2 deubiquitinating enzyme

20 April 2017

1 reference

A dynamic role of HAUSP in the p53-Mdm2 pathway

20 April 2017

1 reference

c-Myc binds to human ribosomal DNA and stimulates transcription of rRNA genes by RNA polymerase I

20 April 2017

1 reference

Myc deletion rescues Apc deficiency in the small intestine

20 April 2017

1 reference

The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells

20 April 2017

1 reference

VHL protein-interacting deubiquitinating enzyme 2 deubiquitinates and stabilizes HIF-1alpha

20 April 2017

1 reference

The ubiquitin ligase HectH9 regulates transcriptional activation by Myc and is essential for tumor cell proliferation

20 April 2017

1 reference

Induction of apoptosis in fibroblasts by c-myc protein

20 April 2017

1 reference

The myc oncogene: MarvelouslY Complex

20 April 2017

1 reference

7 January 2021

Destruction of Myc by ubiquitin-mediated proteolysis: cancer-associated and transforming mutations stabilize Myc.

1 reference

7 January 2021

The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation

1 reference

7 January 2021

A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells

1 reference

7 January 2021

c-Myc proteolysis by the ubiquitin-proteasome pathway: stabilization of c-Myc in Burkitt's lymphoma cells

1 reference

7 January 2021

Aberrant stabilization of c-Myc protein in some lymphoblastic leukemias.

1 reference

7 January 2021

Skp2 regulates Myc protein stability and activity

1 reference

7 January 2021

The F-box protein Skp2 participates in c-Myc proteosomal degradation and acts as a cofactor for c-Myc-regulated transcription

1 reference

7 January 2021

Basal and human papillomavirus E6 oncoprotein-induced degradation of Myc proteins by the ubiquitin pathway

1 reference

7 January 2021

A modified oestrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteins

1 reference

7 January 2021

An shRNA barcode screen provides insight into cancer cell vulnerability to MDM2 inhibitors

1 reference

7 January 2021

The c-Myc protein induces cell cycle progression and apoptosis through dimerization with Max.

1 reference

7 January 2021

Myc requires distinct E2F activities to induce S phase and apoptosis

1 reference

7 January 2021

Specific requirement for Bax, not Bak, in Myc-induced apoptosis and tumor suppression in vivo

1 reference

7 January 2021

C-Myc-independent restoration of multiple phenotypes by two C-Myc target genes with overlapping functions

1 reference

7 January 2021

Stem cell depletion through epidermal deletion of Rac1.

1 reference

7 January 2021

Alterations in the INK4a/ARF locus and their effects on the growth of human osteosarcoma cell lines

1 reference

7 January 2021

SKP2 associates with p130 and accelerates p130 ubiquitylation and degradation in human cells

1 reference

7 January 2021

p45SKP2 promotes p27Kip1 degradation and induces S phase in quiescent cells

1 reference

7 January 2021

A conserved cyclin-binding domain determines functional interplay between anaphase-promoting complex-Cdh1 and cyclin A-Cdk2 during cell cycle progression

1 reference

7 January 2021

A nucleolar isoform of the Fbw7 ubiquitin ligase regulates c-Myc and cell size

1 reference

7 January 2021

Ubiquitylation of cyclin E requires the sequential function of SCF complexes containing distinct hCdc4 isoforms

1 reference

7 January 2021

Direct activation of RNA polymerase III transcription by c-Myc

1 reference

7 January 2021

The Myc trilogy: lord of RNA polymerases.

1 reference

7 January 2021

Accumulation of c-Myc and proteasomes at the nucleoli of cells containing elevated c-Myc protein levels

1 reference

7 January 2021

A conserved element in Myc that negatively regulates its proapoptotic activity

1 reference

7 January 2021

Evasion of the p53 tumour surveillance network by tumour-derived MYC mutants

1 reference

7 January 2021

c-Myc phosphorylation is required for cellular response to oxidative stress

1 reference

7 January 2021

A loss-of-function RNA interference screen for molecular targets in cancer

1 reference

7 January 2021

MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer

1 reference

7 January 2021

Thiol proteases: inhibitors and potential therapeutic targets

1 reference

7 January 2021

Stable suppression of tumorigenicity by virus-mediated RNA interference

1 reference

7 January 2021

Identifiers

DOI

10.1038/NCB1601

1 reference

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

4251007

1021277213

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Fatcat ID

release_7bdbyurxnbek7jglbdnykkpukq

0 references

4251007

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference