Nuclear FAK promotes cell proliferation and survival through FERM-enhanced p53 degradation (Q24307387)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18206965%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

title

Nuclear FAK promotes cell proliferation and survival through FERM-enhanced p53 degradation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18206965%20AND%20SRC:MED&resulttype=core&format=json

Protein tyrosine kinase 2

1 January 2020

main subject

cell biology

0 references

1 reference

regulation of cell population proliferation

GOA release 2020-03-11

1 reference

PTK2 protein tyrosine kinase 2

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Dusko Ilic

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18206965%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

author name string

Ssang-Taek Lim

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18206965%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

Xiao Lei Chen

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18206965%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

Yangmi Lim

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18206965%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

Dan A Hanson

4

1 reference

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1 January 2020

Thanh-Trang Vo

5

1 reference

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1 January 2020

Kyle Howerton

6

1 reference

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1 January 2020

Nicholas Larocque

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18206965%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

Susan J Fisher

8

1 reference

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1 January 2020

David D Schlaepfer

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18206965%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

language of work or name

English

0 references

publication date

1 January 2008

1 reference

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1 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18206965%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

volume

29

1 reference

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1 January 2020

page(s)

9-22

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1 January 2020

issue

1

1 reference

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Structural basis for the autoinhibition of focal adhesion kinase

1 January 2020

cites work

1 reference

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Integrin-regulated FAK-Src signaling in normal and cancer cells

19 March 2017

1 reference

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Direct interaction of the N-terminal domain of focal adhesion kinase with the N-terminal transactivation domain of p53

19 March 2017

1 reference

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PIAS1-mediated sumoylation of focal adhesion kinase activates its autophosphorylation

19 March 2017

1 reference

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Conditional knockout of focal adhesion kinase in endothelial cells reveals its role in angiogenesis and vascular development in late embryogenesis

19 March 2017

1 reference

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Focal adhesion kinase: the first ten years

19 March 2017

1 reference

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Focal adhesion kinase is required for blood vessel morphogenesis

19 March 2017

1 reference

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The p53 pathway: positive and negative feedback loops

19 March 2017

1 reference

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Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

7 April 2017

1 reference

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Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice

7 April 2017

1 reference

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Cellular characterization of a novel focal adhesion kinase inhibitor

7 April 2017

1 reference

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Focal adhesion kinase modulates tension signaling to control actin and focal adhesion dynamics

27 September 2017

1 reference

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FAK is required for axonal sorting by Schwann cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234035

New concepts regarding focal adhesion kinase promotion of cell migration and proliferation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234035

Focal adhesion kinase controls cellular levels of p27/Kip1 and p21/Cip1 through Skp2-dependent and -independent mechanisms.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234035

Intrinsic FAK activity and Y925 phosphorylation facilitate an angiogenic switch in tumors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234035

Endothelial FAK is essential for vascular network stability, cell survival, and lamellipodial formation.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234035

Clinging to life: cell to matrix adhesion and cell survival

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234035

The role of focal-adhesion kinase in cancer - a new therapeutic opportunity

27 September 2017

1 reference

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Residues within the first subdomain of the FERM-like domain in focal adhesion kinase are important in its regulation.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234035

p27Kip1 and cyclin D1 are necessary for focal adhesion kinase regulation of cell cycle progression in glioblastoma cells propagated in vitro and in vivo in the scid mouse brain

27 September 2017

1 reference

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Focal adhesion kinase suppresses apoptosis by binding to the death domain of receptor-interacting protein

27 September 2017

1 reference

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27 September 2017

MDM2, an introduction.

1 reference

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Decision making by p53: life, death and cancer

27 September 2017

1 reference

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The focal adhesion kinase amino-terminal domain localises to nuclei and intercellular junctions in HEK 293 and MDCK cells independently of tyrosine 397 and the carboxy-terminal domain

27 September 2017

1 reference

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Cell attachment to the extracellular matrix induces proteasomal degradation of p21(CIP1) via Cdc42/Rac1 signaling

27 September 2017

1 reference

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Activation of the p53 tumor suppressor protein

27 September 2017

1 reference

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Integrins regulate the apoptotic response to DNA damage through modulation of p53

27 September 2017

1 reference

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Extracellular matrix survival signals transduced by focal adhesion kinase suppress p53-mediated apoptosis.

27 September 2017

1 reference

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Transgenic mouse model for studying the transcriptional activity of the p53 protein: age- and tissue-dependent changes in radiation-induced activation during embryogenesis

27 September 2017

1 reference

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Suppression of p53 activity and p21WAF1/CIP1 expression by vascular cell integrin alphaVbeta3 during angiogenesis

27 September 2017

1 reference

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Enhanced proliferative potential in culture of cells from p53-deficient mice

27 September 2017

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18206965

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Mesodermal defect in late phase of gastrulation by a targeted mutation of focal adhesion kinase, FAK

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18206965

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

1 reference

https://pubmed.ncbi.nlm.nih.gov/18206965

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.MOLCEL.2007.11.031

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18206965%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18206965%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

2 references