Integrin/Fak/Src-mediated regulation of cell survival and anoikis in human intestinal epithelial crypt cells: selective engagement and roles of PI3-K isoform complexes (Q24306865)

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English	Integrin/Fak/Src-mediated regulation of cell survival and anoikis in human intestinal epithelial crypt cells: selective engagement and roles of PI3-K isoform complexes	scientific article

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scholarly article

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Integrin/Fak/Src-mediated regulation of cell survival and anoikis in human intestinal epithelial crypt cells: selective engagement and roles of PI3-K isoform complexes (English)

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Protein tyrosine kinase 2

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GOA release 2020-03-11

Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha

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GOA release 2020-03-11

SRC proto-oncogene, non-receptor tyrosine kinase

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GOA release 2020-03-11

negative regulation of anoikis

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GOA release 2020-03-11

author name string

Marco Beauséjour

1

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Dominique Noël

2

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Sonya Thibodeau

3

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Véronique Bouchard

4

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Charlène Harnois

5

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Jean-François Beaulieu

6

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Marie-Josée Demers

7

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Pierre H Vachon

8

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language of work or name

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publication date

June 2012

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17

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566-78

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6

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https://scigraph.springernature.com/pub.10.1007/s10495-012-0713-6

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Should individual PI3 kinase isoforms be targeted in cancer?

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Integrin-regulated FAK-Src signaling in normal and cancer cells

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Get a ligand, get a life: integrins, signaling and cell survival

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The emerging mechanisms of isoform-specific PI3K signalling

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Targeting PI3K signalling in cancer: opportunities, challenges and limitations

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Isolation, characterization, and culture of normal human intestinal crypt and villus cells

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Apoptosis: why and how does it occur in biology?

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Integrins and signal transduction

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PI3K signaling in neutrophils

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How adhesion signals reach a mitochondrial conclusion--ECM regulation of apoptosis

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Intestinal epithelial cancer cell anoikis resistance: EGFR-mediated sustained activation of Src overrides Fak-dependent signaling to MEK/Erk and/or PI3-K/Akt-1.

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Integrin signalling at a glance

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The life of a cell: apoptosis regulation by the PI3K/PKB pathway

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Class I PI3K in oncogenic cellular transformation.

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27 September 2017

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27 September 2017

Regulation of the Akt kinase by interacting proteins

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Mechanisms of disease: PI3K/AKT signaling in gastrointestinal cancers

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Regulation of Bcl-2 proteins during anoikis and amorphosis.

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Integrin signaling, cell survival, and anoikis: distinctions, differences, and differentiation

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Differentiation state-selective roles of p38 isoforms in human intestinal epithelial cell anoikis

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Human intestinal epithelial cell survival and anoikis. Differentiation state-distinct regulation and roles of protein kinase B/Akt isoforms

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Human intestinal epithelial crypt cell survival and death: Complex modulations of Bcl‐2 homologs by Fak, PI3‐K/Akt‐1, MEK/Erk, and p38 signaling pathways

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B1 integrin/Fak/Src signaling in intestinal epithelial crypt cell survival: integration of complex regulatory mechanisms.

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Can exercise ameliorate the increased risk of cardiovascular disease and diabetes associated with ADT?

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Integrin-linked kinase regulates migration and proliferation of human intestinal cells under a fibronectin-dependent mechanism

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Functional development of human fetal gastrointestinal tract

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Integrin alpha8beta1 confers anoikis susceptibility to human intestinal epithelial crypt cells

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Human intestinal epithelial cell survival: differentiation state-specific control mechanisms

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Fak/Src signaling in human intestinal epithelial cell survival and anoikis: differentiation state-specific uncoupling with the PI3-K/Akt-1 and MEK/Erk pathways

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Cell survival: differences and differentiation]

1 reference

https://pubmed.ncbi.nlm.nih.gov/22402981

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Is Src the key to understanding metastasis and developing new treatments for colon cancer?

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https://pubmed.ncbi.nlm.nih.gov/22402981

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biology of colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/22402981

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/22402981

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S10495-012-0713-6

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