Jump to content

SRC proto-oncogene, non-receptor tyrosine kinase (Q21109354)

From Wikidata
mammalian protein found in Homo sapiens
  • pp60c-src
  • tyrosine kinase pp60c-src
  • SRC
  • v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
  • tyrosine-protein kinase SRC-1
  • p60-Src
  • proto-oncogene c-Src
  • proto-oncogene tyrosine-protein kinase Src
  • protooncogene SRC, Rous sarcoma
edit
Language Label Description Also known as
default for all languages
No label defined
    English
    SRC proto-oncogene, non-receptor tyrosine kinase
    mammalian protein found in Homo sapiens
    • pp60c-src
    • tyrosine kinase pp60c-src
    • SRC
    • v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
    • tyrosine-protein kinase SRC-1
    • p60-Src
    • proto-oncogene c-Src
    • proto-oncogene tyrosine-protein kinase Src
    • protooncogene SRC, Rous sarcoma

    Statements

    image
    PBB Protein SRC image.jpg
    500 × 500; 38 KB
    0 references
    molecular function
    protein binding
    determination method or standard
    IPI
    103 references
    retrieved
    8 April 2019
    stated in
    Molecular chaperone TRAP1 regulates a metabolic switch between mitochondrial respiration and aerobic glycolysis
    GOA
    curator
    UniProt
    UniProt protein ID
    P12931
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Reversion-induced LIM interaction with Src reveals a novel Src inactivation cycle
    GOA
    curator
    UniProt
    UniProt protein ID
    P12931
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    The adaptor protein Tom1L1 is a negative regulator of Src mitogenic signaling induced by growth factors
    GOA
    curator
    UniProt
    UniProt protein ID
    P12931
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    LPS induces pp60c-src-mediated tyrosine phosphorylation of Hsp90 in lung vascular endothelial cells and mouse lung
    GOA
    curator
    UniProt
    UniProt protein ID
    P12931
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    PRR7 is a transmembrane adaptor protein expressed in activated T cells involved in regulation of T cell receptor signaling and apoptosis
    GOA
    curator
    UniProt
    UniProt protein ID
    P12931
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Src kinase phosphorylates RUNX3 at tyrosine residues and localizes the protein in the cytoplasm
    GOA
    curator
    UniProt
    UniProt protein ID
    P12931
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Leptin enhances the potency of circulating angiogenic cells via src kinase and integrin (alpha)vbeta5: implications for angiogenesis in human obesity
    GOA
    curator
    UniProt
    UniProt protein ID
    P12931
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    The tyrosine kinase c-Src enhances RIG-I (retinoic acid-inducible gene I)-elicited antiviral signaling
    GOA
    curator
    UniProt
    UniProt protein ID
    P12931
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    A novel signaling molecule, p130, forms stable complexes in vivo with v-Crk and v-Src in a tyrosine phosphorylation-dependent manner
    GOA
    curator
    UniProt
    UniProt protein ID
    P12931
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Tau interacts with src-family non-receptor tyrosine kinases
    GOA
    curator
    UniProt
    UniProt protein ID
    P12931
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Crystal structure of the conserved core of HIV-1 Nef complexed with a Src family SH3 domain
    GOA
    curator
    UniProt
    UniProt protein ID
    P12931
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Association of pp60c-src with biliary glycoprotein (CD66a), an adhesion molecule of the carcinoembryonic antigen family downregulated in colorectal carcinomas
    GOA
    curator
    UniProt
    UniProt protein ID
    P12931
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    The PDZ protein MPP2 interacts with c-Src in epithelial cells
    GOA
    curator
    UniProt
    UniProt protein ID
    P12931
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    c-Src regulates Akt signaling in response to ghrelin via beta-arrestin signaling-independent and -dependent mechanisms
    GOA
    curator
    UniProt
    UniProt protein ID
    P12931
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Src homology 2 (SH2) domain containing protein tyrosine phosphatase-1 (SHP-1) dephosphorylates VEGF Receptor-2 and attenuates endothelial DNA synthesis, but not migration
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Nuclear PKM2 regulates β-catenin transactivation upon EGFR activation
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    NKX2-1/TITF1/TTF-1-Induced ROR1 is required to sustain EGFR survival signaling in lung adenocarcinoma
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    VHL loss in renal cell carcinoma leads to up-regulation of CUB domain-containing protein 1 to stimulate PKC{delta}-driven migration
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    c-Src is a PDZ interaction partner and substrate of the E3 ubiquitin ligase Ligand-of-Numb protein X1
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Recombinant human erythropoietin antagonizes trastuzumab treatment of breast cancer cells via Jak2-mediated Src activation and PTEN inactivation
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Functional interaction between c-Src and its mitotic target, Sam 68
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Oncogenic association of the Cbp/PAG adaptor protein with the Lyn tyrosine kinase in human B-NHL rafts
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Involvement of Src tyrosine kinase in Escherichia coli invasion of human brain microvascular endothelial cells
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    A human protein-protein interaction network: a resource for annotating the proteome
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Platelet endothelial cell adhesion molecule-1 is phosphorylatable by c-Src, binds Src-Src homology 2 domain, and exhibits immunoreceptor tyrosine-based activation motif-like properties
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Cbl associates with Pyk2 and Src to regulate Src kinase activity, alpha(v)beta(3) integrin-mediated signaling, cell adhesion, and osteoclast motility
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    The SRC-associated protein CUB Domain-Containing Protein-1 regulates adhesion and motility
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Identification of preferred protein interactions by phage-display of the human Src homology-3 proteome
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    An inherent role of microtubule network in the action of nuclear receptor
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    The neurotransmitter dopamine modulates vascular permeability in the endothelium
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Magicin associates with the Src-family kinases and is phosphorylated upon CD3 stimulation
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Mitochondrial AKAP121 binds and targets protein tyrosine phosphatase D1, a novel positive regulator of src signaling
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Translationally controlled tumor protein induces human breast epithelial cell transformation through the activation of Src
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Functional role of c-Src in IL-1-induced NF-kappa B activation: c-Src is a component of the IKK complex
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Rack1 promotes epithelial cell–cell adhesion by regulating E-cadherin endocytosis
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Using an in Situ Proximity Ligation Assay to Systematically Profile Endogenous Protein–Protein Interactions in a Pathway Network
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    ErbB2-mediated Src and signal transducer and activator of transcription 3 activation leads to transcriptional up-regulation of p21Cip1 and chemoresistance in breast cancer cells
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    JMJD6 Regulates ERα Methylation on Arginine
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Role of beta-arrestin 1 in the metastatic progression of colorectal cancer
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Structural basis for a novel intrapeptidyl H-bond and reverse binding of c-Cbl-TKB domain substrates
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Variant estrogen receptor-c-Src molecular interdependence and c-Src structural requirements for endothelial NO synthase activation
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Deficiency of a beta-arrestin-2 signal complex contributes to insulin resistance.
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    The role of protein-tyrosine phosphatase 1B in integrin signaling
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Targeting AMAP1 and cortactin binding bearing an atypical src homology 3/proline interface for prevention of breast cancer invasion and metastasis
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    FAK-MAPK-dependent adhesion disassembly downstream of L1 contributes to semaphorin3A-induced collapse
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    PI3-kinase/Akt-dependent antiapoptotic signaling by the PDGF alpha receptor is negatively regulated by Src family kinases
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Identification and functional characterization of an Src homology domain 3 domain-binding site on Cbl
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Phosphorylation of Tyr1214 within VEGFR-2 triggers the recruitment of Nck and activation of Fyn leading to SAPK2/p38 activation and endothelial cell migration in response to VEGF
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Dosage-dependent switch from G protein-coupled to G protein-independent signaling by a GPCR
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Metalloproteinase/Presenilin1 processing of ephrinB regulates EphB-induced Src phosphorylation and signaling
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Multiple Phosphorylation of Chicken Protein Tyrosine Phosphatase 1 and Human Protein Tyrosine Phosphatase 1B by Casein Kinase II and p60in Vitro
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    ErbB-2 activates Stat3 alpha in a Src- and JAK2-dependent manner
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Phosphorylation of ETS1 by Src family kinases prevents its recognition by the COP1 tumor suppressor
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Bcr-Abl stabilizes beta-catenin in chronic myeloid leukemia through its tyrosine phosphorylation
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    EGFR-mediated Beclin 1 phosphorylation in autophagy suppression, tumor progression, and tumor chemoresistance
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Cysteine mutations cause defective tyrosine phosphorylation in MEGF10 myopathy
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    A quantitative protein interaction network for the ErbB receptors using protein microarrays
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Simultaneous assay of Src SH3 and SH2 domain binding using different wavelength fluorescence polarization probes
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Cyanidin-3-Glucoside inhibits ethanol-induced invasion of breast cancer cells overexpressing ErbB2
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Negative regulation of PYK2/related adhesion focal tyrosine kinase signal transduction by hematopoietic tyrosine phosphatase SHPTP1
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    The tyrosine phosphatase 1B regulates linker for activation of T-cell phosphorylation and platelet aggregation upon FcgammaRIIa cross-linking
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Beta-arrestin1 phosphorylation by GRK5 regulates G protein-independent 5-HT4 receptor signalling
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Integrin/Fak/Src-mediated regulation of cell survival and anoikis in human intestinal epithelial crypt cells: selective engagement and roles of PI3-K isoform complexes
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Identification of protein-tyrosine phosphatase 1B as the major tyrosine phosphatase activity capable of dephosphorylating and activating c-Src in several human breast cancer cell lines
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Phosphorylation-dependent interactions between ADAM15 cytoplasmic domain and Src family protein-tyrosine kinases
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Phospho-tyrosine dependent protein-protein interaction network
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    The rat tyrosine phosphatase eta increases cell adhesion by activating c-Src through dephosphorylation of its inhibitory phosphotyrosine residue
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Ribosomal protein L10 interacts with the SH3 domain and regulates GDNF-induced neurite growth in SH-SY-5y cells
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Characterization of the interactions of estrogen receptor and MNAR in the activation of cSrc
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Activation of rapid oestrogen signalling in aggressive human breast cancers
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Catalytically active membrane-distal phosphatase domain of receptor protein-tyrosine phosphatase alpha is required for Src activation
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Small proline-rich proteins (SPRR) function as SH3 domain ligands, increase resistance to injury and are associated with epithelial-mesenchymal transition (EMT) in cholangiocytes
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Enhanced prediction of Src homology 2 (SH2) domain binding potentials using a fluorescence polarization-derived c-Met, c-Kit, ErbB, and androgen receptor interactome
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Ack1 mediates Cdc42-dependent cell migration and signaling to p130Cas
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Focal adhesion kinase overexpression enhances ras-dependent integrin signaling to ERK2/mitogen-activated protein kinase through interactions with and activation of c-Src
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    A phosphotyrosine displacement mechanism for activation of Src by PTPalpha
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    PTP1B contributes to the oncogenic properties of colon cancer cells through Src activation
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Direct interaction between ER membrane-bound PTP1B and its plasma membrane-anchored targets
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Src kinase becomes preferentially associated with the VEGFR, KDR/Flk-1, following VEGF stimulation of vascular endothelial cells
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    mda-9/Syntenin promotes metastasis in human melanoma cells by activating c-Src
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    The Tensin-3 protein, including its SH2 domain, is phosphorylated by Src and contributes to tumorigenesis and metastasis
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Yes and PI3K bind CD95 to signal invasion of glioblastoma
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Regulation of c-Src by binding to the PDZ domain of AF-6
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    ARAP3 is transiently tyrosine phosphorylated in cells attaching to fibronectin and inhibits cell spreading in a RhoGAP-dependent manner
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    EG-1 interacts with c-Src and activates its signaling pathway
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    c-Src phosphorylation and activation of hexokinase promotes tumorigenesis and metastasis.
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Platelet-endothelial cell adhesion molecule-1 (CD31), a scaffolding molecule for selected catenin family members whose binding is mediated by different tyrosine and serine/threonine phosphorylation
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    p140Cap protein suppresses tumour cell properties, regulating Csk and Src kinase activity
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Phosphorylated alpha-actinin and protein-tyrosine phosphatase 1B coregulate the disassembly of the focal adhesion kinase x Src complex and promote cell migration
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    PTP-1B is an essential positive regulator of platelet integrin signaling
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Epidermal growth factor directs sex-specific steroid signaling through Src activation
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Analysis of protein-protein interactions in cross-talk pathways reveals CRKL protein as a novel prognostic marker in hepatocellular carcinoma
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Beta-arrestin links endothelin A receptor to beta-catenin signaling to induce ovarian cancer cell invasion and metastasis
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    EGFR/Met association regulates EGFR TKI resistance in breast cancer
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Mitotic activation of protein-tyrosine phosphatase alpha and regulation of its Src-mediated transforming activity by its sites of protein kinase C phosphorylation
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Structural characterization of autoinhibited c-Met kinase produced by coexpression in bacteria with phosphatase
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    DOCK8 functions as an adaptor that links TLR-MyD88 signaling to B cell activation
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Deciphering the cross talk between hnRNP K and c-Src: the c-Src activation domain in hnRNP K is distinct from a second interaction site
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    A positive feedback loop of ER-α36/EGFR promotes malignant growth of ER-negative breast cancer cells
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    XB130, a novel adaptor protein for signal transduction
    GOA
    curator
    HUGO Gene Nomenclature Committee
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IPI
    protein tyrosine kinase activity
    determination method or standard
    EXP
    IDA
    IEA
    IMP
    TAS
    19 references
    retrieved
    17 October 2017
    stated in
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P12931&geneProductId=UniProtKB:P12931
    determination method or standard
    TAS
    retrieved
    17 October 2017
    stated in
    Gbetagamma subunits mediate Src-dependent phosphorylation of the epidermal growth factor receptor. A scaffold for G protein-coupled receptor-mediated Ras activation
    GOA
    curator
    Proteome Inc.
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P12931&geneProductId=UniProtKB:P12931
    determination method or standard
    TAS
    retrieved
    17 October 2017
    stated in
    Lipid raft-associated β-adducin is required for PSGL-1-mediated neutrophil rolling on P-selectin
    GOA
    curator
    Critical Assessment of Protein Function Annotation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P12931&geneProductId=UniProtKB:P12931
    determination method or standard
    IMP
    retrieved
    17 October 2017
    stated in
    Tarp regulates early Chlamydia-induced host cell survival through interactions with the human adaptor protein SHC1
    GOA
    curator
    Critical Assessment of Protein Function Annotation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P12931&geneProductId=UniProtKB:P12931
    determination method or standard
    IMP
    retrieved
    17 October 2017
    stated in
    GOA
    curator
    UniProt
    UniProt protein ID
    P12931
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P12931&geneProductId=UniProtKB:P12931
    determination method or standard
    IEA
    retrieved
    17 October 2017
    stated in
    GOA
    curator
    InterPro
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P12931&geneProductId=UniProtKB:P12931
    determination method or standard
    IEA
    retrieved
    17 October 2017
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P12931&geneProductId=UniProtKB:P12931
    determination method or standard
    IEA
    retrieved
    17 October 2017
    stated in
    PKCdelta-dependent functional switch of rpS3 between translation and DNA repair
    GOA
    curator
    UniProt
    UniProt protein ID
    P12931
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P12931&geneProductId=UniProtKB:P12931
    determination method or standard
    IDA
    retrieved
    17 October 2017
    stated in
    Crosstalk between Src and major vault protein in epidermal growth factor-dependent cell signalling
    GOA
    curator
    UniProt
    UniProt protein ID
    P12931
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P12931&geneProductId=UniProtKB:P12931
    determination method or standard
    IDA
    retrieved
    17 October 2017
    stated in
    Steel factor stimulates the tyrosine phosphorylation of the proto-oncogene product, p95vav, in human hemopoietic cells
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P12931&geneProductId=UniProtKB:P12931
    determination method or standard
    EXP
    retrieved
    17 October 2017
    stated in
    Kit signaling through PI 3-kinase and Src kinase pathways: an essential role for Rac1 and JNK activation in mast cell proliferation
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P12931&geneProductId=UniProtKB:P12931
    determination method or standard
    EXP
    retrieved
    17 October 2017
    stated in
    Vav2 is required for cell spreading
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P12931&geneProductId=UniProtKB:P12931
    determination method or standard
    EXP
    retrieved
    17 October 2017
    stated in
    Src kinase phosphorylates RUNX3 at tyrosine residues and localizes the protein in the cytoplasm
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P12931&geneProductId=UniProtKB:P12931
    determination method or standard
    EXP
    retrieved
    17 October 2017
    stated in
    Identification of Src-specific phosphorylation site on focal adhesion kinase: dissection of the role of Src SH2 and catalytic functions and their consequences for tumor cell behavior
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P12931&geneProductId=UniProtKB:P12931
    determination method or standard
    EXP
    retrieved
    17 October 2017
    stated in
    A Src family kinase-Shp2 axis controls RUNX1 activity in megakaryocyte and T-lymphocyte differentiation
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P12931&geneProductId=UniProtKB:P12931
    determination method or standard
    EXP
    retrieved
    17 October 2017
    stated in
    Gab2 is involved in differential phosphoinositide 3-kinase signaling by two splice forms of c-Kit
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P12931&geneProductId=UniProtKB:P12931
    determination method or standard
    EXP
    retrieved
    17 October 2017
    stated in
    Differential involvement of Src family kinases in Fc gamma receptor-mediated phagocytosis
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P12931&geneProductId=UniProtKB:P12931
    determination method or standard
    EXP
    retrieved
    17 October 2017
    stated in
    Differential kinase requirements in human and mouse Fc-gamma receptor phagocytosis and endocytosis
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P12931&geneProductId=UniProtKB:P12931
    determination method or standard
    EXP
    retrieved
    17 October 2017
    stated in
    Tyrosyl phosphorylation of Shp2 is required for normal ERK activation in response to some, but not all, growth factors
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P12931&geneProductId=UniProtKB:P12931
    determination method or standard
    EXP
    protein tyrosine kinase activity
    determination method or standard
    EXP
    IDA
    IEA
    IMP
    NAS
    TAS
    17 references
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    TAS
    retrieved
    8 April 2019
    stated in
    Gbetagamma subunits mediate Src-dependent phosphorylation of the epidermal growth factor receptor. A scaffold for G protein-coupled receptor-mediated Ras activation
    GOA
    curator
    Proteome Inc.
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    TAS
    retrieved
    8 April 2019
    stated in
    Roles of tau protein in health and disease
    GOA
    curator
    ARUK-UCL
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    NAS
    retrieved
    8 April 2019
    stated in
    Tarp regulates early Chlamydia-induced host cell survival through interactions with the human adaptor protein SHC1
    GOA
    curator
    Critical Assessment of Protein Function Annotation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    Lipid raft-associated β-adducin is required for PSGL-1-mediated neutrophil rolling on P-selectin
    GOA
    curator
    Critical Assessment of Protein Function Annotation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    UniProt
    UniProt protein ID
    P12931
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    InterPro
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    Crosstalk between Src and major vault protein in epidermal growth factor-dependent cell signalling
    GOA
    curator
    UniProt
    UniProt protein ID
    P12931
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    PKCdelta-dependent functional switch of rpS3 between translation and DNA repair
    GOA
    curator
    UniProt
    UniProt protein ID
    P12931
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Tyrosyl phosphorylation of Shp2 is required for normal ERK activation in response to some, but not all, growth factors
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    EXP
    retrieved
    8 April 2019
    stated in
    Vav2 is required for cell spreading
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    EXP
    retrieved
    8 April 2019
    stated in
    Src kinase phosphorylates RUNX3 at tyrosine residues and localizes the protein in the cytoplasm
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    EXP
    retrieved
    8 April 2019
    stated in
    Gab2 is involved in differential phosphoinositide 3-kinase signaling by two splice forms of c-Kit
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    EXP
    retrieved
    8 April 2019
    stated in
    Kit signaling through PI 3-kinase and Src kinase pathways: an essential role for Rac1 and JNK activation in mast cell proliferation
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    EXP
    retrieved
    8 April 2019
    stated in
    Identification of Src-specific phosphorylation site on focal adhesion kinase: dissection of the role of Src SH2 and catalytic functions and their consequences for tumor cell behavior
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    EXP
    retrieved
    8 April 2019
    stated in
    Steel factor stimulates the tyrosine phosphorylation of the proto-oncogene product, p95vav, in human hemopoietic cells
    GOA
    curator
    Reactome
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    EXP
    cell component
    biological process
    peptidyl-tyrosine phosphorylation
    determination method or standard
    IDA
    IEA
    IMP
    NAS
    6 references
    retrieved
    8 April 2019
    stated in
    JNK pathway-associated phosphatase dephosphorylates focal adhesion kinase and suppresses cell migration.
    GOA
    curator
    ARUK-UCL
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    NAS
    retrieved
    8 April 2019
    stated in
    Tarp regulates early Chlamydia-induced host cell survival through interactions with the human adaptor protein SHC1
    GOA
    curator
    Critical Assessment of Protein Function Annotation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    Lipid raft-associated β-adducin is required for PSGL-1-mediated neutrophil rolling on P-selectin
    GOA
    curator
    Critical Assessment of Protein Function Annotation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    SPAP2, an Ig family receptor containing both ITIMs and ITAMs
    GOA
    curator
    UniProt
    UniProt protein ID
    P12931
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Interchangeability of Themis1 and Themis2 in Thymocyte Development Reveals Two Related Proteins with Conserved Molecular Function
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12931
    determination method or standard
    IDA

    Identifiers

    MeSH descriptor ID
    D016392
    subject named as
    Proto-Oncogene Proteins pp60(c-src)
    0 references
    Freebase ID
    /m/03cxgjp
    0 references
    Microsoft Academic ID (discontinued)
    108636557
    0 references
    2909360354
    0 references
    2910830915
    0 references
    PDB structure ID
     
    edit
    edit
      edit
        edit
          edit
            edit
              edit
                edit
                  edit
                    Retrieved from "https://www.wikidata.org/w/index.php?title=Q21109354&oldid=2425648134"