Aurora kinase-A inactivates DNA damage-induced apoptosis and spindle assembly checkpoint response functions of p73 (Q24305327)

GOA release 2020-03-11

15

William E Grizzle

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Huamin Wang

16

object named as

Huamin Wang

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Ralph B. Arlinghaus

12

object named as

Ralph B Arlinghaus

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author name string

Hiroshi Katayama

1

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Jin Wang

2

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Warapen Treekitkarnmongkol

3

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Hidehiko Kawai

4

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Kaori Sasai

5

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Hui Zhang

6

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Hua Wang

7

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Henry P Adams

8

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Shoulei Jiang

9

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Sandip N Chakraborty

10

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Fumio Suzuki

11

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Jinsong Liu

13

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James A Mobley

14

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Subrata Sen

Polo-like kinase-1 is activated by aurora A to promote checkpoint recovery

17

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language of work or name

English

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publication date

14 February 2012

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published in

Cancer Cell

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volume

21

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issue

2

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page(s)

196-211

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cites work

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Aurora A kinase activity influences calcium signaling in kidney cells

7 April 2017

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Destabilization of Bcr-Abl/Jak2 Network by a Jak2/Abl Kinase Inhibitor ON044580 Overcomes Drug Resistance in Blast Crisis Chronic Myelogenous Leukemia (CML)

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TAp73 regulates the spindle assembly checkpoint by modulating BubR1 activity

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Aurora kinase A inhibition leads to p73-dependent apoptosis in p53-deficient cancer cells

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TAp73 knockout shows genomic instability with infertility and tumor suppressor functions

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Aurora-A kinase phosphorylation of Aurora-A kinase interacting protein (AIP) and stabilization of the enzyme-substrate complex

27 September 2017

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Role for KAP1 serine 824 phosphorylation and sumoylation/desumoylation switch in regulating KAP1-mediated transcriptional repression

27 September 2017

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RING domain-mediated interaction is a requirement for MDM2's E3 ligase activity

27 September 2017

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Aurora-A induces cell survival and chemoresistance by activation of Akt through a p53-dependent manner in ovarian cancer cells

27 September 2017

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27 September 2017

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WOX1 is essential for tumor necrosis factor-, UV light-, staurosporine-, and p53-mediated cell death, and its tyrosine 33-phosphorylated form binds and stabilizes serine 46-phosphorylated p53.

27 September 2017

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27 September 2017

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27 September 2017

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Aurora-A abrogation of p53 DNA binding and transactivation activity by phosphorylation of serine 215.

27 September 2017

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27 September 2017

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Akt phosphorylates the Yes-associated protein, YAP, to induce interaction with 14-3-3 and attenuation of p73-mediated apoptosis

27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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Inactivation of tumor suppressor p53 by mot-2, a hsp70 family member.

27 September 2017

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Aurora kinase-A regulates kinetochore/chromatin associated microtubule assembly in human cells.

30 May 2018

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Mortalin controls centrosome duplication via modulating centrosomal localization of p53.

29 November 2018

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Phosphorylation by aurora kinase A induces Mdm2-mediated destabilization and inhibition of p53.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3760020

p73 is regulated by phosphorylation at the G2/M transition.

29 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3760020

Overexpression of oncogenic STK15/BTAK/Aurora A kinase in human pancreatic cancer.

29 November 2018

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Roles of aurora-A kinase in mitotic entry and G2 checkpoint in mammalian cells.

29 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3760020

Molecular mechanisms underlying WOX1 activation during apoptotic and stress responses

29 November 2018

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12 December 2020

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p73 suppresses polyploidy and aneuploidy in the absence of functional p53

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