Silencing of OB-RGRP in mouse hypothalamic arcuate nucleus increases leptin receptor signaling and prevents diet-induced obesity (Q24301625)

negative regulation of protein localization to cell surface

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

12

Philippe Froguel

Philippe

Froguel

1 reference

19 October 2023

3

Karin Séron

Karin

Séron

1 reference

19 October 2023

Sandrine Belouzard

4

Sandrine

Belouzard

1 reference

19 October 2023

Julie Dam

8

Julie

Dam

1 reference

19 October 2023

Yves Rouillé

13

Yves

Rouillé

1 reference

19 October 2023

Cyril Couturier

1

Cyril

Couturier

1 reference

19 October 2023

Chamsy Sarkis

2

Chamsy

Sarkis

1 reference

19 October 2023

Patty Chen

5

Patty

Chen

1 reference

19 October 2023

Aude Lenain

6

Aude

Lenain

1 reference

19 October 2023

Laetitia Corset

7

Laetitia

Corset

1 reference

19 October 2023

Virginie Vauthier

9

Virginie

Vauthier

1 reference

19 October 2023

Anne Dubart

10

Anne

Dubart

1 reference

19 October 2023

Jacques Mallet

11

Jacques

Mallet

1 reference

19 October 2023

Ralf Jockers

14

Ralf

Proceedings of the National Academy of Sciences of the United States of America

Jockers

1 reference

19 October 2023

language of work or name

English

0 references

publication date

4 December 2007

0 references

published in

0 references

volume

104

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issue

49

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page(s)

19476-81

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cites work

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Two defects contribute to hypothalamic leptin resistance in mice with diet-induced obesity

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The leptin receptor promoter controls expression of a second distinct protein

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Yeast Vps55p, a functional homolog of human obesity receptor gene-related protein, is involved in late endosome to vacuole trafficking

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Induction of leptin resistance through direct interaction of C-reactive protein with leptin

27 September 2017

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Three novel beta-propeller mutations causing Glanzmann thrombasthenia result in production of normally stable pro-alphaIIb, but variably impaired progression of pro-alphaIIbbeta3 from endoplasmic reticulum to Golgi

27 September 2017

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Low levels of expression of leptin receptor at the cell surface result from constitutive endocytosis and intracellular retention in the biosynthetic pathway.

27 September 2017

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27 September 2017

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27 September 2017

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B219/OB-R 5'-UTR and leptin receptor gene-related protein gene expression in mouse brain and placenta: tissue-specific leptin receptor promoter activity

27 September 2017

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The pancreatic beta cell is a key site for mediating the effects of leptin on glucose homeostasis.

21 January 2018

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The hypothalamic arcuate nucleus: a key site for mediating leptin's effects on glucose homeostasis and locomotor activity

21 January 2018

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Five patients with biochemical and/or clinical generalized glucocorticoid resistance without alterations in the glucocorticoid receptor gene.

21 January 2018

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WHIM syndromes with different genetic anomalies are accounted for by impaired CXCR4 desensitization to CXCL12

21 January 2018

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The HIV-1 DNA flap stimulates HIV vector-mediated cell transduction in the brain.

21 January 2018

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Functional properties of leptin receptor isoforms: internalization and degradation of leptin and ligand-induced receptor downregulation

21 January 2018

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Roles for leptin receptor/STAT3-dependent and -independent signals in the regulation of glucose homeostasis

21 January 2018

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Coregulation of two embedded gene products, choline acetyltransferase and the vesicular acetylcholine transporter

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18042720

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Subcellular localization and internalization of the four human leptin receptor isoforms

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18042720

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Both proteasomes and lysosomes degrade the activated erythropoietin receptor

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18042720

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0706671104

1 reference

release_wpesgfdi6bgtbifqmju22pmuge

0 references

0 references

2301263

1 reference

1 reference

1 reference