The ins and outs of leptin receptor activation (Q35163929)

6 August 2017

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title

The ins and outs of leptin receptor activation (English)

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6 August 2017

5

Joël Vandekerckhove

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author name string

Lennart Zabeau

1

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6 August 2017

Delphine Lavens

2

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6 August 2017

Frank Peelman

3

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6 August 2017

Sven Eyckerman

4

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6 August 2017

Jan Tavernier

6

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6 August 2017

language of work or name

English

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publication date

1 July 2003

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6 August 2017

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6 August 2017

546

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6 August 2017

1

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6 August 2017

45-50

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Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice

6 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900440-X

Positional cloning of the mouse obese gene and its human homologue

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900440-X

Congenital leptin deficiency is associated with severe early-onset obesity in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900440-X

A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900440-X

The stomach is a source of leptin

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900440-X

Identification and expression cloning of a leptin receptor, OB-R

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900440-X

Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900440-X

Effects of recombinant leptin therapy in a child with congenital leptin deficiency.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900440-X

Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900440-X

Recombinant leptin for weight loss in obese and lean adults: a randomized, controlled, dose-escalation trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900440-X

Two defects contribute to hypothalamic leptin resistance in mice with diet-induced obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900440-X

Leptin: a review of its peripheral actions and interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900440-X

Modulation of insulin activities by leptin

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900440-X

Generation of soluble leptin receptor by ectodomain shedding of membrane-spanning receptors in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900440-X

Receptor recognition by gp130 cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900440-X

Structure of an extracellular gp130 cytokine receptor signaling complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900440-X

Identification of ligand-binding site III on the immunoglobulin-like domain of the granulocyte colony-stimulating factor receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900440-X

Structure of the extracellular domains of the human interleukin-6 receptor alpha -chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900440-X

Homology modeling of human leptin/leptin receptor complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900440-X

Subcloning, expression, purification, and characterization of recombinant human leptin-binding domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900440-X

Separate functions for the two modules of the membrane-proximal cytokine binding domain of glycoprotein 190, the leukemia inhibitory factor low affinity receptor, in ligand binding and receptor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900440-X

Leptin receptor (OB-R) signaling. Cytoplasmic domain mutational analysis and evidence for receptor homo-oligomerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900440-X

Membrane distal cytokine binding domain of LIFR interacts with soluble CNTFR in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900440-X

A functional role of the membrane-proximal extracellular domains of the signal transducer gp130 in heterodimerization with the leukemia inhibitory factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900440-X

Ligand-independent dimerization of the extracellular domain of the leptin receptor and determination of the stoichiometry of leptin binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900440-X

Abnormal splicing of the leptin receptor in diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900440-X

Regulation of Jak kinases by intracellular leptin receptor sequences.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900440-X

Enhancing leptin response by preventing SH2-containing phosphatase 2 interaction with Ob receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900440-X

STAT3 signalling is required for leptin regulation of energy balance but not reproduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900440-X

Leptin activation of Stat3 in the hypothalamus of wild-type and ob/ob mice but not db/db mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900440-X

The full-length leptin receptor has signaling capabilities of interleukin 6-type cytokine receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900440-X

Leptin receptor activation of SH2 domain containing protein tyrosine phosphatase 2 modulates Ob receptor signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900440-X

SOCS3 mediates feedback inhibition of the leptin receptor via Tyr985

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900440-X

Identification of the Y985 and Y1077 motifs as SOCS3 recruitment sites in the murine leptin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900440-X

Activation of downstream signals by the long form of the leptin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900440-X

Identification of SOCS-3 as a potential mediator of central leptin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900440-X

Leptin differentially regulates NPY and POMC neurons projecting to the lateral hypothalamic area.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900440-X

Divergent roles of SHP-2 in ERK activation by leptin receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900440-X

Tyrosine-phosphorylated SOCS-3 inhibits STAT activation but binds to p120 RasGAP and activates Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900440-X

Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900440-X

Targeted and extended acetylation of histones H4 and H3 at active and inactive genes in chicken embryo erythrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900440-X

Molecular basis for the dephosphorylation of the activation segment of the insulin receptor by protein tyrosine phosphatase 1B

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900440-X

Protein tyrosine phosphatase 1B negatively regulates leptin signaling in a hypothalamic cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900440-X

The nontransmembrane tyrosine phosphatase PTP-1B localizes to the endoplasmic reticulum via its 35 amino acid C-terminal sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900440-X

Tyrosine phosphorylation of p97 regulates transitional endoplasmic reticulum assembly in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900440-X

Selective interaction between leptin and insulin signaling pathways in a hepatic cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900440-X

Intracellular signalling. Key enzyme in leptin-induced anorexia

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900440-X

The effect of leptin on Lep expression is tissue-specific and nutritionally regulated

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900440-X

Localization of leptin binding domain in the leptin receptor.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900440-X

Identification of the critical sequence elements in the cytoplasmic domain of leptin receptor isoforms required for Janus kinase/signal transducer and activator of transcription activation by receptor heterodimers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900440-X

TYK2 and JAK2 are substrates of protein-tyrosine phosphatase 1B

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900440-X

10.1016/S0014-5793(03)00440-X

7 January 2021

Identifiers

DOI

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6 August 2017

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