Vimentin is a novel AKT1 target mediating motility and invasion (Q24300375)

13

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Gordon B. Mills

14

object named as

G B Mills

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author name string

Q-S Zhu

1

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K Rosenblatt

2

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K-L Huang

3

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G Lahat

4

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R Brobey

5

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S Bolshakov

6

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T Nguyen

7

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Z Ding

8

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R Belousov

9

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K Bill

10

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X Luo

11

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M-C Hung

15

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D Lev

Protein kinase A phosphorylates and regulates dimerization of 14-3-3 epsilon

16

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language of work or name

English

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publication date

27 January 2011

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published in

Oncogene

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volume

30

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page(s)

457-70

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issue

4

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cites work

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Akt blocks breast cancer cell motility and invasion through the transcription factor NFAT

19 March 2017

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PKCepsilon-mediated phosphorylation of vimentin controls integrin recycling and motility

19 March 2017

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Inactivation of the glial fibrillary acidic protein gene, but not that of vimentin, improves neuronal survival and neurite growth by modifying adhesion molecule expression

19 March 2017

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Changes in nuclear morphology during apoptosis correlate with vimentin cleavage by different caspases located either upstream or downstream of Bcl-2 action

19 March 2017

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Identification of phosphorylation-induced changes in vimentin intermediate filaments by site-directed spin labeling and electron paramagnetic resonance

19 March 2017

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Soft tissue sarcoma cells are highly sensitive to AKT blockade: a role for p53-independent up-regulation of GADD45 alpha

27 September 2017

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Phosphorylation of human insulin receptor substrate-1 at Serine 629 plays a positive role in insulin signaling

27 September 2017

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Requirement of Ca2+ influx- and phosphatidylinositol 3-kinase-mediated m-calpain activity for shear stress-induced endothelial cell polarity

27 September 2017

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Down-regulation of vimentin expression inhibits carcinoma cell migration and adhesion

27 September 2017

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Akt1 governs breast cancer progression in vivo

27 September 2017

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Phosphorylation of beta-catenin by AKT promotes beta-catenin transcriptional activity

27 September 2017

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Mechanism of Akt1 inhibition of breast cancer cell invasion reveals a protumorigenic role for TSC2.

27 September 2017

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Distinct roles of Akt1 and Akt2 in regulating cell migration and epithelial-mesenchymal transition

27 September 2017

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Soft-tissue sarcomas in adults

27 September 2017

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Fibroblast growth factor-2-mediated capillary morphogenesis of endothelial cells requires signals via Flt-1/vascular endothelial growth factor receptor-1: possible involvement of c-Akt

27 September 2017

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PTEN: from pathology to biology

27 September 2017

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The protein kinase Akt induces epithelial mesenchymal transition and promotes enhanced motility and invasiveness of squamous cell carcinoma lines.

27 September 2017

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Overexpression of AKT2/protein kinase Bbeta leads to up-regulation of beta1 integrins, increased invasion, and metastasis of human breast and ovarian cancer cells

27 September 2017

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Akt1 and Akt2 differently regulate muscle creatine kinase and myogenin gene transcription in insulin-induced differentiation of C2C12 myoblasts

27 September 2017

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Caspase cleavage of vimentin disrupts intermediate filaments and promotes apoptosis

27 September 2017

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AKT activation up-regulates insulin-like growth factor I receptor expression and promotes invasiveness of human pancreatic cancer cells.

27 September 2017

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RhoA-binding kinase alpha translocation is facilitated by the collapse of the vimentin intermediate filament network

27 September 2017

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Experimental co-expression of vimentin and keratin intermediate filaments in human breast cancer cells results in phenotypic interconversion and increased invasive behavior.

27 September 2017

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Mice lacking vimentin develop and reproduce without an obvious phenotype

27 September 2017

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Proteolysis of vimentin and desmin by the Ca2+-activated proteinase specific for these intermediate filament proteins

27 September 2017

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Recruitment of vimentin to the cell surface by beta3 integrin and plectin mediates adhesion strength

27 September 2017

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Pathological angiogenesis is induced by sustained Akt signaling and inhibited by rapamycin.

30 May 2018

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Akt1/protein kinase Balpha is critical for ischemic and VEGF-mediated angiogenesis

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Activation of Akt-1 (PKB-alpha) can accelerate ErbB-2-mediated mammary tumorigenesis but suppresses tumor invasion

30 May 2018

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Prognostic importance of epithelial-mesenchymal transition-related protein expression in gastric carcinoma.

21 January 2018

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Akt1 ablation inhibits, whereas Akt2 ablation accelerates, the development of mammary adenocarcinomas in mouse mammary tumor virus (MMTV)-ErbB2/neu and MMTV-polyoma middle T transgenic mice

21 January 2018

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Prognostic significance of activated AKT expression in soft-tissue sarcoma.

21 January 2018

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Impaired mechanical stability, migration and contractile capacity in vimentin-deficient fibroblasts.

21 January 2018

1 reference

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Metastasis suppressors and the tumor microenvironment

29 November 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.421

Phosphorylation of vimentin by Rho-associated kinase at a unique amino-terminal site that is specifically phosphorylated during cytokinesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.421

The AKT-mTOR pathway plays a critical role in the development of leiomyosarcomas

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.421

31 March 2020

Identifiers

DOI

10.1038/ONC.2010.421

1 reference

Dimensions Publication ID

3633474

1046739907

0 references

3633474

1 reference

1 reference

1 reference