RIP1 is required for IAP inhibitor-mediated sensitization of childhood acute leukemia cells to chemotherapy-induced apoptosis (Q24299986)

Receptor interacting serine/threonine kinase 1

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tumor necrosis factor

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positive regulation of apoptotic process

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1 reference

1 reference

S Fulda

11

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Irmela Jeremias

object named as

I Jeremias

9

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Peter Vandenabeele

object named as

P Vandenabeele

8

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author name string

S Löder

1

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M Fakler

2

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H Schoeneberger

3

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S Cristofanon

4

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J Leibacher

5

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N Vanlangenakker

6

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M J M Bertrand

7

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K-M Debatin

Integrating molecular information into treatment of childhood acute lymphoblastic leukemia--a perspective from the BFM Study Group

10

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language of work or name

English

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publication date

May 2012

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published in

Leukemia

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volume

26

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issue

5

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page(s)

1020-9

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cites work

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https://api.crossref.org/works/10.1038%2FLEU.2011.353

Tumor resistance to apoptosis

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2011.353

Therapeutic opportunities for counteracting apoptosis resistance in childhood leukaemia

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2011.353

Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2011.353

Targeting the extrinsic apoptosis pathway in cancer

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2011.353

Mitochondrial membrane permeabilization in cell death

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2011.353

IAP-targeted therapies for cancer

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2011.353

Human inhibitor of apoptosis proteins: why XIAP is the black sheep of the family

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2011.353

cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2011.353

RIP1, a kinase on the crossroads of a cell's decision to live or die

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.353

IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2011.353

IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2011.353

TNF-alpha induces two distinct caspase-8 activation pathways

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2011.353

XIAP expression is post-transcriptionally upregulated in childhood ALL and is associated with glucocorticoid response in T-cell ALL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.353

Small molecule XIAP inhibitors cooperate with TRAIL to induce apoptosis in childhood acute leukemia cells and overcome Bcl-2-mediated resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.353

Discovery of potent antagonists of the antiapoptotic protein XIAP for the treatment of cancer

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2011.353

Regulation of TRAIL-induced apoptosis by XIAP in pancreatic carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.353

Autocrine TNFalpha signaling renders human cancer cells susceptible to Smac-mimetic-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.353

Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.353

Identification of RIP1 kinase as a specific cellular target of necrostatins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.353

Small molecule XIAP inhibitors enhance TRAIL-induced apoptosis and antitumor activity in preclinical models of pancreatic carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.353

Small-molecule XIAP inhibitors enhance gamma-irradiation-induced apoptosis in glioblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.353

A novel paradigm to trigger apoptosis in chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.353

Inhibitor of apoptosis proteins in hematological malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.353

A novel method for the combined flow cytometric analysis of cell cycle and cytochrome c release

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.353

Acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.353