HGAL, a germinal center specific protein, decreases lymphoma cell motility by modulation of the RhoA signaling pathway (Q24299894)

1

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Xiaoqing Lu

2

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George McNamara

3

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Xiaofei Liu

4

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Elena Cubedo

5

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Kristopher A Sarosiek

6

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Isidro Sánchez-García

7

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David M Helfman

HGAL, a lymphoma prognostic biomarker, interacts with the cytoskeleton and mediates the effects of IL-6 on cell migration

8

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language of work or name

English

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publication date

9 December 2010

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published in

Blood

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volume

116

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issue

24

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page(s)

5217-27

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cites work

1 reference

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T-cell protein tyrosine phosphatase, distinctively expressed in activated-B-cell-like diffuse large B-cell lymphomas, is the nuclear phosphatase of STAT6

19 March 2017

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Identification of a novel sequence in PDZ-RhoGEF that mediates interaction with the actin cytoskeleton

19 March 2017

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Two newly characterized germinal center B-cell-associated genes, GCET1 and GCET2, have differential expression in normal and neoplastic B cells

19 March 2017

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Direct interaction of insulin-like growth factor-1 receptor with leukemia-associated RhoGEF

19 March 2017

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Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)

19 March 2017

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Cell migration: integrating signals from front to back

19 March 2017

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Rho GTPases in cell biology

19 March 2017

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Myosin phosphatase: structure, regulation and function

19 March 2017

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Homo- and hetero-oligomerization of PDZ-RhoGEF, LARG and p115RhoGEF by their C-terminal region regulates their in vivo Rho GEF activity and transforming potential

19 March 2017

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Plexin B regulates Rho through the guanine nucleotide exchange factors leukemia-associated Rho GEF (LARG) and PDZ-RhoGEF

19 March 2017

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Regulation of G protein-linked guanine nucleotide exchange factors for Rho, PDZ-RhoGEF, and LARG by tyrosine phosphorylation: evidence of a role for focal adhesion kinase

19 March 2017

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RGS-containing RhoGEFs: the missing link between transforming G proteins and Rho?

19 March 2017

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The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF

19 March 2017

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M17, a gene specific for germinal center (GC) B cells and a prognostic marker for GC B-cell lymphomas, is dispensable for the GC reaction in mice

19 March 2017

1 reference

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GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors

19 March 2017

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Human germinal center-associated lymphoma protein expression is associated with improved failure-free survival in Brazilian patients with classical Hodgkin lymphoma

7 April 2017

1 reference

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Differentiation stage-specific expression of microRNAs in B lymphocytes and diffuse large B-cell lymphomas

27 September 2017

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Cofilin determines the migration behavior and turning frequency of metastatic cancer cells

27 September 2017

1 reference

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The cofilin pathway in breast cancer invasion and metastasis

27 September 2017

1 reference

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Studies of a germinal centre B-cell expressed gene, GCET2, suggest its role as a membrane associated adapter protein.

27 September 2017

1 reference

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In vivo imaging of germinal centres reveals a dynamic open structure

27 September 2017

1 reference

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Big roles for small GTPases in the control of directed cell movement

27 September 2017

1 reference

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Expression of the human germinal center-associated lymphoma (HGAL) protein identifies a subset of classic Hodgkin lymphoma of germinal center derivation and improved survival

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012539

Regulation of myosin II during cytokinesis in higher eukaryotes

27 September 2017

1 reference

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PAK and other Rho-associated kinases--effectors with surprisingly diverse mechanisms of regulation

27 September 2017

1 reference

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Citron kinase, a Rho-dependent kinase, induces di-phosphorylation of regulatory light chain of myosin II

27 September 2017

1 reference

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RhoA inactivation by p190RhoGAP regulates cell spreading and migration by promoting membrane protrusion and polarity

27 September 2017

1 reference

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Distinct roles of ROCK (Rho-kinase) and MLCK in spatial regulation of MLC phosphorylation for assembly of stress fibers and focal adhesions in 3T3 fibroblasts.

27 September 2017

1 reference

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Effector domain mutants of Rho dissociate cytoskeletal changes from nuclear signaling and cellular transformation

27 September 2017

1 reference

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M17: a novel gene expressed in germinal centers.

27 September 2017

1 reference

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A novel role for Lsc/p115 RhoGEF and LARG in regulating RhoA activity downstream of adhesion to fibronectin.

27 September 2017

1 reference

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Expression of the human germinal center-associated lymphoma (HGAL) protein, a new marker of germinal center B-cell derivation

30 May 2018

1 reference

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Tumorigenic activity of rho genes from Aplysia californica

30 May 2018

1 reference

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Expression of the human germinal-centre-associated lymphoma protein in diffuse large B-cell lymphomas in patients with rheumatoid arthritis

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012539

In vivo imaging studies shed light on germinal-centre development

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012539

Definition of germinal-center B cell migration in vivo reveals predominant intrazonal circulation patterns.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012539

Myosin IIA regulates cell motility and actomyosin–microtubule crosstalk

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012539

Imaging of germinal center selection events during affinity maturation

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012539

Prediction of survival in diffuse large-B-cell lymphoma based on the expression of six genes

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012539

Measurement of the levels of polymerized actin (F-actin) in chemokine-stimulated lymphocytes and GFP-coupled cDNA transfected lymphoid cells by flow cytometry

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012539

HGAL is a novel interleukin-4-inducible gene that strongly predicts survival in diffuse large B-cell lymphoma.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012539

Rho-kinase contributes to diphosphorylation of myosin II regulatory light chain in nonmuscle cells

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012539

Lsc is required for marginal zone B cells, regulation of lymphocyte motility and immune responses

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012539

10.1182/BLOOD-2010-04-281568

29 November 2018

Identifiers

DOI

1 reference

3566289

3566289

1 reference

1 reference

1 reference