The Grb2/PLD2 interaction is essential for lipase activity, intracellular localization and signaling in response to EGF (Q24295239)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17276458%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

title

The Grb2/PLD2 interaction is essential for lipase activity, intracellular localization and signaling in response to EGF (English)

1 reference

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25 December 2019

author

Julián Gómez-Cambronero

5

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25 December 2019

author name string

Mauricio Di Fulvio

1

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25 December 2019

Kathleen Frondorf

2

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25 December 2019

Karen M Henkels

3

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25 December 2019

Nicholas Lehman

4

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25 December 2019

language of work or name

English

0 references

publication date

12 January 2007

1 reference

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Journal of Molecular Biology

25 December 2019

published in

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25 December 2019

volume

367

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25 December 2019

page(s)

814-824

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25 December 2019

issue

3

1 reference

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The elucidation of novel SH2 binding sites on PLD2

25 December 2019

cites work

1 reference

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Cloning and initial characterization of a human phospholipase D2 (hPLD2). ADP-ribosylation factor regulates hPLD2

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Ash/Grb-2, a SH2/SH3-containing protein, couples to signaling for mitogenesis and cytoskeletal reorganization by EGF and PDGF

19 March 2017

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The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling

19 March 2017

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SH2 domains recognize specific phosphopeptide sequences

19 March 2017

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Role for phospholipase D in receptor-mediated endocytosis

19 March 2017

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PLD2 complexes with the EGF receptor and undergoes tyrosine phosphorylation at a single site upon agonist stimulation

19 March 2017

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Characterization of two alternately spliced forms of phospholipase D1. Activation of the purified enzymes by phosphatidylinositol 4,5-bisphosphate, ADP-ribosylation factor, and Rho family monomeric GTP-binding proteins and protein kinase C-alpha

19 March 2017

1 reference

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Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling

19 March 2017

1 reference

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The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1

19 March 2017

1 reference

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Grb2/Ash binds directly to tyrosines 1068 and 1086 and indirectly to tyrosine 1148 of activated human epidermal growth factor receptors in intact cells

19 March 2017

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ADP-ribosylation factor-dependent phospholipase D2 activation is required for agonist-induced mu-opioid receptor endocytosis

19 March 2017

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Phospholipase D2 is localized to the rims of the Golgi apparatus in mammalian cells

19 March 2017

1 reference

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Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation

19 March 2017

1 reference

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Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav

7 April 2017

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The uncovering of a novel regulatory mechanism for PLD2: formation of a ternary complex with protein tyrosine phosphatase PTP1B and growth factor receptor-bound protein GRB2.

7 April 2017

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27 September 2017

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The regulation of phospholipase D by inositol phospholipids and small GTPases

27 September 2017

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Coordinated traffic of Grb2 and Ras during epidermal growth factor receptor endocytosis visualized in living cells

27 September 2017

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Role of Grb2 in EGF-stimulated EGFR internalization.

27 September 2017

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27 September 2017

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Compartmentalization of SHC, GRB2 and mSOS, and hyperphosphorylation of Raf-1 by EGF but not insulin in liver parenchyma.

27 September 2017

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Presence of a phospholipase D (PLD) distinct from PLD1 or PLD2 in human neutrophils: immunobiochemical characterization and initial purification.

27 September 2017

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The phox homology domain of phospholipase D activates dynamin GTPase activity and accelerates EGFR endocytosis.

30 May 2018

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29 November 2018

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Interaction of EGF receptor and grb2 in living cells visualized by fluorescence resonance energy transfer (FRET) microscopy

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17276458

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.JMB.2007.01.021

1 reference

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25 December 2019

1 reference

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25 December 2019

1 reference