The ubiquitin ligase itch regulates apoptosis by targeting thioredoxin-interacting protein for ubiquitin-dependent degradation (Q24294762)

Itchy E3 ubiquitin protein ligase

GOA release 2020-03-11

1 reference

ubiquitin protein ligase binding

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

Pingzhao Zhang

1

Pingzhao

Zhang

1 reference

20 October 2023

Chenji Wang

2

Chenji

Wang

1 reference

20 October 2023

Kun Gao

3

Kun

Gao

1 reference

20 October 2023

Dejie Wang

4

Dejie

Wang

1 reference

20 October 2023

Jun Mao

5

Jun

Mao

1 reference

20 October 2023

Jian An

6

Jian

An

1 reference

20 October 2023

Chen Xu

7

Chen

Xu

1 reference

20 October 2023

Di Wu

8

Di

Wu

1 reference

20 October 2023

Hongxiu Yu

9

Hongxiu

Yu

1 reference

20 October 2023

Jun O Liu

10

Jun O

Liu

1 reference

20 October 2023

Long Yu

11

Long

Journal of Biological Chemistry

Yu

1 reference

20 October 2023

language of work or name

English

0 references

publication date

19 March 2010

0 references

published in

0 references

volume

285

0 references

issue

12

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page(s)

8869-79

0 references

cites work

Nedd4 and Nedd4-2: closely related ubiquitin-protein ligases with distinct physiological functions

1 reference

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Quantitative proteomics reveals the function of unconventional ubiquitin chains in proteasomal degradation

19 March 2017

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A quantitative atlas of mitotic phosphorylation

19 March 2017

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The ubiquitin-protein ligase Itch regulates p73 stability

19 March 2017

1 reference

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The expression of vitamin D-upregulated protein 1 in skin and its interaction with sciellin in cultured keratinocytes

19 March 2017

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19 March 2017

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19 March 2017

1 reference

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The ubiquitin ligase itch is auto-ubiquitylated in vivo and in vitro but is protected from degradation by interacting with the deubiquitylating enzyme FAM/USP9X

19 March 2017

1 reference

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Importin alpha1 (Rch1) mediates nuclear translocation of thioredoxin-binding protein-2/vitamin D(3)-up-regulated protein 1

19 March 2017

1 reference

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Heat shock factor regulates VDUP1 gene expression

19 March 2017

1 reference

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Melanoma metastasis suppression by chromosome 6: evidence for a pathway regulated by CRSP3 and TXNIP

19 March 2017

1 reference

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Vitamin D3-upregulated protein-1 (VDUP-1) regulates redox-dependent vascular smooth muscle cell proliferation through interaction with thioredoxin

19 March 2017

1 reference

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Themes and variations on ubiquitylation

19 March 2017

1 reference

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Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

19 March 2017

1 reference

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ITCH is a putative target for a novel 20q11.22 amplification detected in anaplastic thyroid carcinoma cells by array-based comparative genomic hybridization.

7 April 2017

1 reference

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Quantitative analysis of global ubiquitination in HeLa cells by mass spectrometry

27 September 2017

1 reference

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The HECT family of E3 ubiquitin ligases: multiple players in cancer development

27 September 2017

1 reference

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Itch: a HECT-type E3 ligase regulating immunity, skin and cancer

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2838308

Glucose sensing by MondoA:Mlx complexes: a role for hexokinases and direct regulation of thioredoxin-interacting protein expression

27 September 2017

1 reference

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Txnip balances metabolic and growth signaling via PTEN disulfide reduction

27 September 2017

1 reference

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Thioredoxin-interacting protein: a critical link between glucose toxicity and beta-cell apoptosis

27 September 2017

1 reference

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Diverse functions of VDUP1 in cell proliferation, differentiation, and diseases

27 September 2017

1 reference

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Thioredoxin and thioredoxin-binding protein-2 in cancer and metabolic syndrome

27 September 2017

1 reference

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Itch inhibition regulates chemosensitivity in vitro

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2838308

TXNIP regulates peripheral glucose metabolism in humans

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2838308

Extracellular thioredoxin and thioredoxin-binding protein 2 in control of cancer

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2838308

Vitamin D3 upregulated protein 1 (VDUP1) is a regulator for redox signaling and stress-mediated diseases

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2838308

Role of thioredoxin in cell growth through interactions with signaling molecules

27 September 2017

1 reference

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The E3 ubiquitin ligase Itch controls the protein stability of p63

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2838308

The Nedd4 family of E3 ubiquitin ligases: functional diversity within a common modular architecture

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2838308

MDM2 promotes ubiquitination and degradation of MDMX

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2838308

Proteasome inhibitors: from research tools to drug candidates

27 September 2017

1 reference

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Hepatocellular carcinoma in Txnip-deficient mice.

27 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.063321

Impaired fatty acid utilization in thioredoxin binding protein-2 (TBP-2)-deficient mice: a unique animal model of Reye syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.063321

Thioredoxin-interacting protein (Txnip) is a critical regulator of hepatic glucose production

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.063321

Mice lacking thioredoxin-interacting protein provide evidence linking cellular redox state to appropriate response to nutritional signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.063321

Ceramide induces p38 MAPK and JNK activation through a mechanism involving a thioredoxin-interacting protein-mediated pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.063321

Thioredoxin-interacting protein (txnip) is a glucocorticoid-regulated primary response gene involved in mediating glucocorticoid-induced apoptosis

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20068034

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M109.063321

1 reference

release_qcxfx6qz7zdstp7y7flhy3227a

419580

Fatcat ID

0 references

419580

1 reference

1 reference

1 reference