thioredoxin interacting protein (Q21122281)

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mammalian protein found in Homo sapiens

thioredoxin binding protein 2
TXNIP
upregulated by 1,25-dihydroxyvitamin D-3
thioredoxin-interacting protein
Thioredoxin-binding protein 2
vitamin D3 up-regulated protein 1

Language	Label	Description	Also known as
English	thioredoxin interacting protein	mammalian protein found in Homo sapiens	thioredoxin binding protein 2 TXNIP upregulated by 1,25-dihydroxyvitamin D-3 thioredoxin-interacting protein Thioredoxin-binding protein 2 vitamin D3 up-regulated protein 1

Statements

1 reference

13 November 2019

UniProt protein ID

Immunoglobulin E-set

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9H3M7

Arrestin, C-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9H3M7

Arrestin C-terminal-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Arrestin-like, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

enzyme inhibitor activity

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3M7

determination method

protein binding

determination method

5 references

8 April 2019

TXNIP interacts with hEcd to increase p53 stability and activity

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3M7

determination method

8 April 2019

The expression of vitamin D-upregulated protein 1 in skin and its interaction with sciellin in cultured keratinocytes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3M7

determination method

8 April 2019

TXNIP interacts with hEcd to increase p53 stability and activity

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3M7

determination method

8 April 2019

Structural basis for a novel interaction between TXNIP and Vav2

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3M7

determination method

8 April 2019

A possible interaction of thioredoxin with VDUP1 in HeLa cells detected in a yeast two-hybrid system

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3M7

determination method

ubiquitin protein ligase binding

determination method

1 reference

8 April 2019

The ubiquitin ligase itch regulates apoptosis by targeting thioredoxin-interacting protein for ubiquitin-dependent degradation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3M7

determination method

determination method

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3M7

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3M7

determination method

8 April 2019

The expression of vitamin D-upregulated protein 1 in skin and its interaction with sciellin in cultured keratinocytes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3M7

determination method

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3M7

determination method

mitochondrial intermembrane space

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3M7

determination method

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3M7

determination method

biological process

cellular response to tumor cell

determination method

1 reference

8 April 2019

hnRNP G elicits tumor-suppressive activity in part by upregulating the expression of Txnip

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3M7

determination method

response to estradiol

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3M7

determination method

negative regulation of catalytic activity

determination method

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3M7

determination method

regulation of transcription, DNA-templated

determination method

1 reference

31 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9H3M7&geneProductId=UniProtKB:Q9H3M7

determination method

protein import into nucleus

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3M7

determination method

response to progesterone

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3M7

determination method

response to mechanical stimulus

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3M7

determination method

negative regulation of transcription by RNA polymerase II

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3M7

determination method

response to glucose

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3M7

determination method

response to oxidative stress

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3M7

determination method

transcription, DNA-templated

determination method

1 reference

31 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9H3M7&geneProductId=UniProtKB:Q9H3M7

determination method

keratinocyte differentiation

determination method

1 reference

8 April 2019

The expression of vitamin D-upregulated protein 1 in skin and its interaction with sciellin in cultured keratinocytes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3M7

determination method

response to calcium ion

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3M7

determination method

negative regulation of cell division

determination method

1 reference

8 April 2019

hnRNP G elicits tumor-suppressive activity in part by upregulating the expression of Txnip

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3M7

determination method

regulation of cell population proliferation

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3M7

determination method

positive regulation of apoptotic process

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3M7

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3M7

determination method

platelet-derived growth factor receptor signaling pathway

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3M7

determination method

response to hydrogen peroxide

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3M7

determination method

signal transduction

determination method

1 reference

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9H3M7&geneProductId=UniProtKB:Q9H3M7

determination method

Arrestin-like, N-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9H3M7

Arrestin C-terminal-like domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9H3M7

Identifiers

MeSH descriptor ID

subject named as

TXNIP protein, human

0 references

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000396322

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000396322

ENSP00000462521

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000462521

0 references

Microsoft Academic ID

0 references

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

PDB structure ID

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

based on heuristic

inferred by common MeSH mappings on source and on Wikidata

25 May 2023

Sitelinks

Wikipedia(8 entries)

arwiki TXNIP
cawiki TXNIP
dewiki TXNIP
enwiki TXNIP
idwiki TXNIP
jawiki TXNIP
ttwiki TXNIP
ukwiki TXNIP

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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