Structural basis for recruitment of Ubc12 by an E2 binding domain in NEDD8's E1 (Q24293794)

NEDD8 ubiquitin like modifier

GOA release 2020-03-11

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ubiquitin protein ligase binding

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

Danny T Huang

1

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Amir Paydar

2

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Min Zhuang

3

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M Brett Waddell

4

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James M Holton

5

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Brenda A Schulman

The ubiquitin system: pathogenesis of human diseases and drug targeting

6

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publication date

4 February 2005

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language of work or name

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17

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issue

3

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page(s)

341-50

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cites work

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An altered-specificity ubiquitin-conjugating enzyme/ubiquitin-protein ligase pair

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Structural aspects of non-ribosomal peptide biosynthesis

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Structural model of the UbcH5B/CNOT4 complex revealed by combining NMR, mutagenesis, and docking approaches.

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Determinants of Functionality in the Ubiquitin Conjugating Enzyme Family

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Nedd8-modification of Cul1 is promoted by Roc1 as a Nedd8-E3 ligase and regulates its stability

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Conformation of Polypeptides and Proteins

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Processing of X-ray diffraction data collected in oscillation mode

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Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases

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7 January 2021

Structural basis for E2-mediated SUMO conjugation revealed by a complex between ubiquitin-conjugating enzyme Ubc9 and RanGAP1

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Structural basis for phosphodependent substrate selection and orientation by the SCFCdc4 ubiquitin ligase

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Solution structure of a CUE-ubiquitin complex reveals a conserved mode of ubiquitin binding

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Mechanism of ubiquitin recognition by the CUE domain of Vps9p

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A superfamily of protein tags: ubiquitin, SUMO and related modifiers

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Structure of a conjugating enzyme-ubiquitin thiolester intermediate reveals a novel role for the ubiquitin tail

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Conformational flexibility underlies ubiquitin ligation mediated by the WWP1 HECT domain E3 ligase

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Structure of a beta-TrCP1-Skp1-beta-catenin complex: destruction motif binding and lysine specificity of the SCF(beta-TrCP1) ubiquitin ligase

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7 January 2021

The structure of the APPBP1-UBA3-NEDD8-ATP complex reveals the basis for selective ubiquitin-like protein activation by an E1

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Ubiquitin recognition by the human TSG101 protein

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The 1.75 A crystal structure of acetyl-CoA synthetase bound to adenosine-5'-propylphosphate and coenzyme A

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Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

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Insights into the ubiquitin transfer cascade from the structure of the activating enzyme for NEDD8

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Grabbing E2 by the tail

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A unique E1-E2 interaction required for optimal conjugation of the ubiquitin-like protein NEDD8

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Ubiquitin interactions of NZF zinc fingers

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Nedd8 on cullin: building an expressway to protein destruction.

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7 January 2021

The UbcH8 ubiquitin E2 enzyme is also the E2 enzyme for ISG15, an IFN-alpha/beta-induced ubiquitin-like protein

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Surface hydrophobic residues of multiubiquitin chains essential for proteolytic targeting

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Crystal structure of murine/human Ubc9 provides insight into the variability of the ubiquitin-conjugating system

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The binding interface between an E2 (UBC9) and a ubiquitin homologue (UBL1).

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Distinct functional surface regions on ubiquitin

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Identification of a multifunctional binding site on Ubc9p required for Smt3p conjugation

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Protein interactions within the N-end rule ubiquitin ligation pathway

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Structural insights into endosomal sorting complex required for transport (ESCRT-I) recognition of ubiquitinated proteins.

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Structural basis for the activation of phenylalanine in the non-ribosomal biosynthesis of gramicidin S

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NEDD8 recruits E2-ubiquitin to SCF E3 ligase.

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7 January 2021

Solution structure of Vps27 UIM-ubiquitin complex important for endosomal sorting and receptor downregulation

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7 January 2021

A conserved catalytic residue in the ubiquitin-conjugating enzyme family.

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The Rbx1 subunit of SCF and VHL E3 ubiquitin ligase activates Rub1 modification of cullins Cdc53 and Cul2

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Improved methods for building protein models in electron density maps and the location of errors in these models

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Structure of ubiquitin-conjugating enzyme 9 displays significant differences with other ubiquitin-conjugating enzymes which may reflect its specificity for sumo rather than ubiquitin

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

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Automated MAD and MIR structure solution

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7 January 2021

Structure of the VHL-ElonginC-ElonginB complex: implications for VHL tumor suppressor function

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7 January 2021

Structure of an E6AP-UbcH7 complex: insights into ubiquitination by the E2-E3 enzyme cascade

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7 January 2021

The Saccharomyces cerevisiae DNA repair gene RAD23 encodes a nuclear protein containing a ubiquitin-like domain required for biological function

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Novel CDC34 (UBC3) ubiquitin-conjugating enzyme mutants obtained by charge-to-alanine scanning mutagenesis

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7 January 2021

Interferon-inducible ubiquitin E2, Ubc8, is a conjugating enzyme for protein ISGylation

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7 January 2021

Protein modification by SUMO

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7 January 2021