Nedd8 on cullin: building an expressway to protein destruction. (Q33976667)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15021886%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

title

Nedd8 on cullin: building an expressway to protein destruction (English)

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25 December 2019

2

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25 December 2019

author name string

Zhen-Qiang Pan

1

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25 December 2019

Dora C Dias

3

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25 December 2019

Kosj Yamoah

4

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25 December 2019

Kenneth Wu

5

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25 December 2019

publication date

1 March 2004

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25 December 2019

language of work or name

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25 December 2019

volume

23

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25 December 2019

issue

11

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25 December 2019

page(s)

1985-1997

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publication type of scholarly work

25 December 2019

review article

1 reference

Targeted disruption of p185/Cul7 gene results in abnormal vascular morphogenesis

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UV-damaged DNA-binding Proteins Are Targets of CUL-4A-mediated Ubiquitination and Degradation

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AXR1-ECR1-dependent conjugation of RUB1 to the Arabidopsis Cullin AtCUL1 is required for auxin response

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The ubiquitin-related protein RUB1 and auxin response in Arabidopsis

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Exclusion of germ plasm proteins from somatic lineages by cullin-dependent degradation

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The RUB/Nedd8 conjugation pathway is required for early development in Arabidopsis

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CUL7: A DOC domain-containing cullin selectively binds Skp1.Fbx29 to form an SCF-like complex

21 January 2018

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The COP9 Signalosome Promotes Degradation of Cyclin E during Early Drosophila Oogenesis

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C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

21 January 2018

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A Complex of Cdc4p, Skp1p, and Cdc53p/Cullin Catalyzes Ubiquitination of the Phosphorylated CDK Inhibitor Sic1p

21 January 2018

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CUL-2 is required for the G1-to-S-phase transition and mitotic chromosome condensation in Caenorhabditis elegans

21 January 2018

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Targeting of protein ubiquitination by BTB–Cullin 3–Roc1 ubiquitin ligases

21 January 2018

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Activation of UBC5 ubiquitin-conjugating enzyme by the RING finger of ROC1 and assembly of active ubiquitin ligases by all cullins

21 January 2018

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The CUL1 C-terminal sequence and ROC1 are required for efficient nuclear accumulation, NEDD8 modification, and ubiquitin ligase activity of CUL1

21 January 2018

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Identification and characterization of DEN1, a deneddylase of the ULP family

21 January 2018

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The cell-cycle regulatory protein Cks1 is required for SCF(Skp2)-mediated ubiquitinylation of p27

21 January 2018

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Identification of a novel isopeptidase with dual specificity for ubiquitin- and NEDD8-conjugated proteins

21 January 2018

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Identification of the activating and conjugating enzymes of the NEDD8 conjugation pathway

21 January 2018

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The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage

21 January 2018

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The ts41 mutation in Chinese hamster cells leads to successive S phases in the absence of intervening G2, M, and G1

21 January 2018

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Covalent modification of all members of human cullin family proteins by NEDD8

21 January 2018

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HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

21 January 2018

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The NED-8 conjugating system in Caenorhabditis elegans is required for embryogenesis and terminal differentiation of the hypodermis

21 January 2018

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Targeting of NEDD8 and its conjugates for proteasomal degradation by NUB1

21 January 2018

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Muf1, a novel Elongin BC-interacting leucine-rich repeat protein that can assemble with Cul5 and Rbx1 to reconstitute a ubiquitin ligase

21 January 2018

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The Rbx1 subunit of SCF and VHL E3 ubiquitin ligase activates Rub1 modification of cullins Cdc53 and Cul2

21 January 2018

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Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase

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Activation of HIF1alpha ubiquitination by a reconstituted von Hippel-Lindau (VHL) tumor suppressor complex

21 January 2018

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NEDD8 recruits E2-ubiquitin to SCF E3 ligase.

21 January 2018

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cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family

21 January 2018

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An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of beta-catenin

21 January 2018

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NUB1, a NEDD8-interacting protein, is induced by interferon and down-regulates the NEDD8 expression

21 January 2018

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Apc10 and Ste9/Srw1, two regulators of the APC–cyclosome, as well as the CDK inhibitor Rum1 are required for G1 cell-cycle arrest in fission yeast

21 January 2018

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Cytoskeletal regulation by the Nedd8 ubiquitin-like protein modification pathway

21 January 2018

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Modification of yeast Cdc53p by the ubiquitin-related protein rub1p affects function of the SCFCdc4 complex

21 January 2018

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21 January 2018

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21 January 2018

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Rub1p processing by Yuh1p is required for wild-type levels of Rub1p conjugation to Cdc53p

21 January 2018

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Cop9/signalosome subunits and Pcu4 regulate ribonucleotide reductase by both checkpoint-dependent and -independent mechanisms

21 January 2018

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NEDD8 modification of CUL1 dissociates p120(CAND1), an inhibitor of CUL1-SKP1 binding and SCF ligases

21 January 2018

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Promotion of NEDD-CUL1 conjugate cleavage by COP9 signalosome

21 January 2018

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Disruption of the COP9 signalosome Csn2 subunit in mice causes deficient cell proliferation, accumulation of p53 and cyclin E, and early embryonic death

21 January 2018

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NEDP1, a highly conserved cysteine protease that deNEDDylates Cullins

21 January 2018

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A role for Saccharomyces cerevisiae Cul8 ubiquitin ligase in proper anaphase progression

21 January 2018

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TIP120A associates with cullins and modulates ubiquitin ligase activity

21 January 2018

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beta-catenin signaling and cancer

21 January 2018

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Modification of cullin-1 by ubiquitin-like protein Nedd8 enhances the activity of SCF(skp2) toward p27(kip1).

21 January 2018

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Nedd8-modification of Cul1 is promoted by Roc1 as a Nedd8-E3 ligase and regulates its stability

21 January 2018

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The Caenorhabditis elegans Skp1-related gene family: diverse functions in cell proliferation, morphogenesis, and meiosis

21 January 2018

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Parc: a cytoplasmic anchor for p53.

21 January 2018

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An intact NEDD8 pathway is required for Cullin-dependent ubiquitylation in mammalian cells

21 January 2018

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ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity

21 January 2018

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A new NEDD8-ligating system for cullin-4A

21 January 2018

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Preferential interaction of TIP120A with Cul1 that is not modified by NEDD8 and not associated with Skp1.

21 January 2018

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Distinct protein degradation mechanisms mediated by Cul1 and Cul3 controlling Ci stability in Drosophila eye development.

21 January 2018

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Doc1 mediates the activity of the anaphase-promoting complex by contributing to substrate recognition.

21 January 2018

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Cdc53 is a scaffold protein for multiple Cdc34/Skp1/F-box proteincomplexes that regulate cell division and methionine biosynthesis in yeast

21 January 2018

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Mechanisms underlying ubiquitination

21 January 2018

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Neddylation and deneddylation of CUL-3 is required to target MEI-1/Katanin for degradation at the meiosis-to-mitosis transition in C. elegans.

21 January 2018

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The BTB protein MEL-26 is a substrate-specific adaptor of the CUL-3 ubiquitin-ligase.

21 January 2018

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A Nedd8 conjugation pathway is essential for proteolytic targeting of p27Kip1 by ubiquitination

21 January 2018

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Degradation of p53 by adenovirus E4orf6 and E1B55K proteins occurs via a novel mechanism involving a Cullin-containing complex

21 January 2018

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Nedd8 modification of cul-1 activates SCF(beta(TrCP))-dependent ubiquitination of IkappaBalpha

21 January 2018

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Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes

21 January 2018

1 reference

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Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells

21 January 2018

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Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34

21 January 2018

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Cullin 4A associates with the UV-damaged DNA-binding protein DDB

21 January 2018

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F-Box Proteins Are Receptors that Recruit Phosphorylated Substrates to the SCF Ubiquitin-Ligase Complex

21 January 2018

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Reconstitution of G1 cyclin ubiquitination with complexes containing SCFGrr1 and Rbx1.

21 January 2018

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Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line

21 January 2018

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Recruitment of a ROC1-CUL1 ubiquitin ligase by Skp1 and HOS to catalyze the ubiquitination of I kappa B alpha

21 January 2018

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The NEDD8 system is essential for cell cycle progression and morphogenetic pathway in mice

21 January 2018

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Simian virus 40 large T antigen binds a novel Bcl-2 homology domain 3-containing proapoptosis protein in the cytoplasm.

21 January 2018

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Cleavage of the C-Terminus of NEDD8 by UCH-L3

21 January 2018

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Identification of NEDD8-conjugation site in human cullin-2

21 January 2018

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Insights into the ubiquitin transfer cascade from the structure of the activating enzyme for NEDD8

21 January 2018

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CSN1 N-terminal-dependent activity is required for Arabidopsis development but not for Rub1/Nedd8 deconjugation of cullins: a structure-function study of CSN1 subunit of COP9 signalosome

21 January 2018

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Crystal structure of the human ubiquitin-like protein NEDD8 and interactions with ubiquitin pathway enzymes

21 January 2018

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The F-box protein Skp2 is a ubiquitylation target of a Cul1-based core ubiquitin ligase complex: evidence for a role of Cul1 in the suppression of Skp2 expression in quiescent fibroblasts

21 January 2018

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Conjugation of Nedd8 to CUL1 enhances the ability of the ROC1-CUL1 complex to promote ubiquitin polymerization

21 January 2018

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The Nedd8-conjugated ROC1-CUL1 Core Ubiquitin Ligase Utilizes Nedd8 Charged Surface Residues for Efficient Polyubiquitin Chain Assembly Catalyzed by Cdc34

21 January 2018

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The SCF(HOS/beta-TRCP)-ROC1 E3 ubiquitin ligase utilizes two distinct domains within CUL1 for substrate targeting and ubiquitin ligation

21 January 2018

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DEN1 is a dual function protease capable of processing the C terminus of Nedd8 and deconjugating hyper-neddylated CUL1

21 January 2018

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BTB proteins are substrate-specific adaptors in an SCF-like modular ubiquitin ligase containing CUL-3.

21 January 2018

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COP9 signalosome subunit 3 is essential for maintenance of cell proliferation in the mouse embryonic epiblast

21 January 2018

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The COP9 signalosome inhibits p27(kip1) degradation and impedes G1-S phase progression via deneddylation of SCF Cul1.

21 January 2018

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Ubiquitin-like proteins: new wines in new bottles

21 January 2018

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Identification of a Cullin Homology Region in a Subunit of the Anaphase-Promoting Complex

21 January 2018

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Mass spectrometric analysis of the anaphase-promoting complex from yeast: identification of a subunit related to cullins.

21 January 2018

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CUL-4A stimulates ubiquitylation and degradation of the HOXA9 homeodomain protein

21 January 2018

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CAND1 binds to unneddylated CUL1 and regulates the formation of SCF ubiquitin E3 ligase complex

21 January 2018

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Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex

21 January 2018

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CUL-4 ubiquitin ligase maintains genome stability by restraining DNA-replication licensing

21 January 2018

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The fission yeast COP9/signalosome is involved in cullin modification by ubiquitin-related Ned8p

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207414

Fission yeast COP9/signalosome suppresses cullin activity through recruitment of the deubiquitylating enzyme Ubp12p

21 January 2018

1 reference

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Interactions of the COP9 Signalosome with the E3 Ubiquitin Ligase SCFTIR1 in Mediating Auxin Response

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1038/SJ.ONC.1207414

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15021886%20AND%20SRC:MED&resulttype=core&format=json

Dimensions publication ID

25 December 2019

1023651648

0 references

1 reference