Crystal structure of human platelet-derived growth factor BB (Q24293538)

identical protein binding

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

C Oefner

1

0 references

A D'Arcy

2

0 references

F K Winkler

3

0 references

B Eggimann

4

0 references

M Hosang

Platelet-derived growth factor: identification of constituent polypeptide chains

5

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language of work or name

English

0 references

publication date

November 1992

0 references

published in

The EMBO Journal

0 references

volume

11

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page(s)

3921-6

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issue

11

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cites work

1 reference

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Two different subunits associate to create isoform-specific platelet-derived growth factor receptors

19 March 2017

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19 March 2017

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Two PDGF-B chain residues, arginine 27 and isoleucine 30, mediate receptor binding and activation

19 March 2017

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Platelet-derived growth factor: purification and partial characterization

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New protein fold revealed by a 2.3-A resolution crystal structure of nerve growth factor

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Resolution of phase ambiguity in macromolecular crystallography

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Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors

7 April 2017

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Primate origin of the cell-derived sequences of simian sarcoma virus

7 April 2017

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Molecular cloning and comparative analyses of the genomes of simian sarcoma virus and its associated helper virus

27 September 2017

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Molecular cloning of integrated simian sarcoma virus: genome organization of infectious DNA clones

27 September 2017

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Blockade of autocrine stimulation in simian sarcoma virus-transformed cells reverses down-regulation of platelet-derived growth factor receptors

27 September 2017

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A platelet-dependent serum factor that stimulates the proliferation of arterial smooth muscle cells in vitro

27 September 2017

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The B chain of PDGF alone is sufficient for mitogenesis

27 September 2017

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Identification of nonessential disulfide bonds and altered conformations in the v-sis protein, a homolog of the B chain of platelet-derived growth factor

27 September 2017

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Immunochemical localization of the epitope for a monoclonal antibody that neutralizes human platelet-derived growth factor mitogenic activity

27 September 2017

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A small v-sis/platelet-derived growth factor (PDGF) B-protein domain in which subtle conformational changes abrogate PDGF receptor interaction and transforming activity

27 September 2017

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Role of alpha beta receptor heterodimer formation in beta platelet-derived growth factor (PDGF) receptor activation by PDGF-AB.

27 September 2017

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Purification of human platelet-derived growth factor

27 September 2017

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The Growth and Preliminary Investigation of Protein and Nucleic Acid Crystals for X-ray Diffraction Analysis

27 September 2017

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Transforming potential of human c-sis nucleotide sequences encoding platelet-derived growth factor.

27 September 2017

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Expression of a Platelet-Derived Growth Factor-Like Protein in Simian Sarcoma Virus Transformed Cells

30 May 2018

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Platelet-derived growth factor is structurally related to the putative transforming protein p28sis of simian sarcoma virus

30 May 2018

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Platelet-derived growth factor. Specific binding to target cells

30 May 2018

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Platelet-derived growth factor. II. Specific binding to cultured cells

30 May 2018

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The v-sis transforming gene of simian sarcoma virus is a new onc gene of primate origin

30 May 2018

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Transforming protein of simian sarcoma virus stimulates autocrine growth of SSV-transformed cells through PDGF cell-surface receptors

30 May 2018

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Platelets as a source of fibroblast growth-promoting activity.

30 May 2018

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C-type virus in tumor tissue of a woolly monkey (Lagothrix spp.) with fibrosarcoma.

30 May 2018

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Synthesis and secondary-structure determination of omega-conotoxin GVIA: a 27-peptide with three intramolecular disulfide bonds

30 May 2018

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The role of individual cysteine residues in the structure and function of the v-sis gene product.

30 May 2018

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Molecular localization of the transforming and secretory properties of PDGF A and PDGF B.

30 May 2018

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Molecular recognition between serine proteases and new bioactive microproteins with a knotted structure

30 May 2018

1 reference

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Ligand-induced interaction between alpha- and beta-type platelet-derived growth factor (PDGF) receptors: role of receptor heterodimers in kinase activation

30 May 2018

1 reference

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Cellular response to platelet-derived growth factor (PDGF)-AB after down-regulation of PDGF alpha-receptors. Evidence that functional binding does not require alpha-receptors

30 May 2018

1 reference

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Identification of three amino acids in the platelet-derived growth factor (PDGF) B-chain that are important for binding to the PDGF beta-receptor.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556902

Platelet alpha granules contain a growth factor for fibroblasts

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556902

Growth factors: Mechanism of action and relation to oncogenes

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556902

Simian Sarcoma Virus—Transformed Cells Secrete a Mitogen Identical to Platelet-Derived Growth Factor

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556902

Simian Sarcoma Virus onc Gene, v- sis , Is Derived from the Gene (or Genes) Encoding a Platelet-Derived Growth Factor

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556902

In Vivo Identification of the Transforming Gene Product of Simian Sarcoma Virus

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556902

Human platelet-derived growth factor. Purification and resolution into two active protein fractions

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/1396586

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Inhibition of neointimal smooth muscle accumulation after angioplasty by an antibody to PDGF

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/1396586