Design, synthesis and characterization of peptidomimetic conjugate of BODIPY targeting HER2 protein extracellular domain (Q24293331)

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1 March 2020

title

Design, synthesis and characterization of peptidomimetic conjugate of BODIPY targeting HER2 protein extracellular domain (English)

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1 March 2020

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5

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1 March 2020

author name string

Sashikanth Banappagari

1

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1 March 2020

Alecia McCall

2

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1 March 2020

Krystal Fontenot

3

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1 March 2020

M Graca H Vicente

4

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1 March 2020

Seetharama Satyanarayanajois

6

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1 March 2020

language of work or name

English

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publication date

28 April 2013

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European Journal of Medicinal Chemistry

1 March 2020

published in

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1 March 2020

volume

65

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1 March 2020

page(s)

60-69

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Epidermal growth factor receptor dimerization and activation require ligand-induced conformational changes in the dimer interface

1 March 2020

cites work

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Crystal structure of the complex of human epidermal growth factor and receptor extracellular domains

19 March 2017

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Structural Evidence for Loose Linkage between Ligand Binding and Kinase Activation in the Epidermal Growth Factor Receptor

19 March 2017

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HER2 phosphorylation is maintained by a PKB negative feedback loop in response to anti-HER2 herceptin in breast cancer

19 March 2017

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An open-and-shut case? Recent insights into the activation of EGF/ErbB receptors

19 March 2017

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ERBB receptors and cancer: the complexity of targeted inhibitors

19 March 2017

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Inhibition of protein-protein interaction of HER2-EGFR and HER2-HER3 by a rationally designed peptidomimetic

7 April 2017

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Phthalocyanine-peptide conjugates for epidermal growth factor receptor targeting

27 September 2017

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27 September 2017

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Structure-activity relationship of conformationally constrained peptidomimetics for antiproliferative activity in HER2-overexpressing breast cancer cell lines

27 September 2017

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Detection of antigen interactions ex vivo by proximity ligation assay: endogenous dopamine D2-adenosine A2A receptor complexes in the striatum

27 September 2017

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A conformationally constrained peptidomimetic binds to the extracellular region of HER2 protein

27 September 2017

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Targeting the dimerization of epidermal growth factor receptors with small-molecule inhibitors

27 September 2017

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HER2- and EGFR-specific affiprobes: novel recombinant optical probes for cell imaging

27 September 2017

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Design, synthesis, and docking studies of peptidomimetics based on HER2-herceptin binding site with potential antiproliferative activity against breast cancer cell lines

27 September 2017

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A 2-helix small protein labeled with 68Ga for PET imaging of HER2 expression

27 September 2017

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Novel anticancer targets: revisiting ERBB2 and discovering ERBB3.

27 September 2017

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Dimeric HER2-specific affibody molecules inhibit proliferation of the SKBR-3 breast cancer cell line

27 September 2017

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All EGF(ErbB) receptors have preformed homo- and heterodimeric structures in living cells.

27 September 2017

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A central role for HER3 in HER2-amplified breast cancer: implications for targeted therapy

27 September 2017

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Structure-based view of epidermal growth factor receptor regulation

27 September 2017

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The chemistry of fluorescent bodipy dyes: versatility unsurpassed

27 September 2017

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BODIPY dyes and their derivatives: syntheses and spectroscopic properties.

27 September 2017

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HER2 therapy. HER2 (ERBB2): functional diversity from structurally conserved building blocks

27 September 2017

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Herceptin: mechanisms of action and resistance

27 September 2017

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Conformational HER-2/neu B-cell epitope peptide vaccine designed to incorporate two native disulfide bonds enhances tumor cell binding and antitumor activities

27 September 2017

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Active and inactive conformations of the epidermal growth factor receptor

27 September 2017

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Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex

27 September 2017

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HER-2-targeted therapy: lessons learned and future directions.

27 September 2017

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Biologic and therapeutic role of HER2 in cancer

27 September 2017

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HER2-Mediated Effects on EGFR Endosomal Sorting: Analysis of Biophysical Mechanisms

27 September 2017

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Role of extracellular subdomains of p185c-neu and the epidermal growth factor receptor in ligand-independent association and transactivation

27 September 2017

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Quantitative analysis of HER2-mediated effects on HER2 and epidermal growth factor receptor endocytosis: distribution of homo- and heterodimers depends on relative HER2 levels

27 September 2017

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Protein detection using proximity-dependent DNA ligation assays.

27 September 2017

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Mutagenesis reveals a role for epidermal growth factor receptor extracellular subdomain IV in ligand binding

27 September 2017

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ErbB-2 amplification inhibits down-regulation and induces constitutive activation of both ErbB-2 and epidermal growth factor receptors.

27 September 2017

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Tyrosine kinase inhibition: an approach to drug development

27 September 2017

1 reference

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Epidermal growth factor receptor controls flat dysplastic aberrant crypt foci development and colon cancer progression in the rat azoxymethane model

27 September 2017

1 reference

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Solid-phase peptide synthesis: from standard procedures to the synthesis of difficult sequences.

29 November 2018

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Disabling receptor ensembles with rationally designed interface peptidomimetics

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3740721

Dimers of dipyrrometheneboron difluoride (BODIPY) with light spectroscopic applications in chemistry and biology

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3740721

HER2 inhibition: from discovery to clinical practice

29 November 2018

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12 December 2020

Synthesis and Characterization of Near-Infrared Absorbing Benzannulated Aza-BODIPY Dyes

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12 December 2020

Quantum dots-based immunofluorescence technology for the quantitative determination of HER2 expression in breast cancer

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12 December 2020

Coregulation of epidermal growth factor receptor/human epidermal growth factor receptor 2 (HER2) levels and locations: quantitative analysis of HER2 overexpression effects

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12 December 2020

10.1016/J.EJMECH.2013.04.038

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1 March 2020

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1 March 2020

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