Impaired dopaminergic neurotransmission and microtubule-associated protein tau alterations in human LRRK2 transgenic mice (Q24293070)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20659558%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

title

Impaired dopaminergic neurotransmission and microtubule-associated protein tau alterations in human LRRK2 transgenic mice (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20659558%20AND%20SRC:MED&resulttype=core&format=json

Leucine rich repeat kinase 2

8 February 2020

main subject

microtubule

0 references

1 reference

positive regulation of dopamine receptor signaling pathway

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1 reference

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20659558%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Adam Braithwaite

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20659558%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Dennis W. Dickson

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20659558%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Matthew J. Farrer

27

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20659558%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

author name string

H L Melrose

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20659558%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

J C Dächsel

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20659558%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

B Behrouz

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20659558%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

S J Lincoln

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20659558%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

M Yue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20659558%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

K M Hinkle

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20659558%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

C B Kent

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20659558%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

E Korvatska

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20659558%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

J P Taylor

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20659558%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

L Witten

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20659558%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Y-Q Liang

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20659558%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

J E Beevers

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20659558%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

M Boules

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20659558%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

V A Serna

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20659558%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

A Gaukhman

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20659558%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

X Yu

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20659558%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

M Castanedes-Casey

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20659558%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

S Ogholikhan

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20659558%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

N Yu

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20659558%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

D Bass

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20659558%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

G Tyndall

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20659558%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

G D Schellenberg

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20659558%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

C Janus

26

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20659558%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

language of work or name

English

0 references

publication date

24 July 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20659558%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

published in

Neurobiology of Disease

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20659558%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

volume

40

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20659558%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20659558%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

page(s)

503-517

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20659558%20AND%20SRC:MED&resulttype=core&format=json

Genome-wide association study reveals genetic risk underlying Parkinson's disease

8 February 2020

cites work

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Role of autophagy in G2019S-LRRK2-associated neurite shortening in differentiated SH-SY5Y cells

19 March 2017

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Localization of LRRK2 to membranous and vesicular structures in mammalian brain

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The familial Parkinsonism gene LRRK2 regulates neurite process morphology

19 March 2017

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Microtubule-associated protein/microtubule affinity-regulating kinase (p110mark). A novel protein kinase that regulates tau-microtubule interactions and dynamic instability by phosphorylation at the Alzheimer-specific site serine 262

19 March 2017

1 reference

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Loss of leucine-rich repeat kinase 2 causes impairment of protein degradation pathways, accumulation of alpha-synuclein, and apoptotic cell death in aged mice

19 March 2017

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Clinical and pathologic features of families with LRRK2-associated Parkinson's disease

19 March 2017

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Staging of neurofibrillary degeneration caused by human tau overexpression in a unique cellular model of human tauopathy

19 March 2017

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Enhanced striatal dopamine transmission and motor performance with LRRK2 overexpression in mice is eliminated by familial Parkinson's disease mutation G2019S

19 March 2017

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Leucine-rich repeat kinase 2 associates with lipid rafts

19 March 2017

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A functional role for adult hippocampal neurogenesis in spatial pattern separation

19 March 2017

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Leucine-rich repeat kinase 2 regulates the progression of neuropathology induced by Parkinson's-disease-related mutant alpha-synuclein.

7 April 2017

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Unexpected lack of hypersensitivity in LRRK2 knock-out mice to MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine).

27 September 2017

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R1441C mutation in LRRK2 impairs dopaminergic neurotransmission in mice.

27 September 2017

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Leucine-rich repeat kinase 2 mutations and Parkinson's disease: three questions

27 September 2017

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Leucine-rich repeat kinase 2 phosphorylates brain tubulin-beta isoforms and modulates microtubule stability--a point of convergence in parkinsonian neurodegeneration?

27 September 2017

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Mutant LRRK2(R1441G) BAC transgenic mice recapitulate cardinal features of Parkinson's disease

27 September 2017

1 reference

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Dentate gyrus-specific knockdown of adult neurogenesis impairs spatial and object recognition memory in adult rats

27 September 2017

1 reference

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Tau pathophysiology in neurodegeneration: a tangled issue

27 September 2017

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Progression of dopaminergic dysfunction in a LRRK2 kindred: a multitracer PET study

27 September 2017

1 reference

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Modeling PD pathogenesis in mice: advantages of a chronic MPTP protocol

27 September 2017

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LRRK2 Gly2019Ser penetrance in Arab-Berber patients from Tunisia: a case-control genetic study

27 September 2017

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27 September 2017

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The Roc domain of leucine-rich repeat kinase 2 is sufficient for interaction with microtubules

27 September 2017

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A comparative analysis of leucine-rich repeat kinase 2 (Lrrk2) expression in mouse brain and Lewy body disease

27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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Constitutive Alzheimer's-type tau epitopes in a neuritogenic rat CNS cell line

27 September 2017

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Psychopharmacology of dopamine: the contribution of comparative studies in inbred strains of mice

27 September 2017

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Hippocampus-dependent learning is associated with adult neurogenesis in MRL/MpJ mice

27 September 2017

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Intramolecular activation mechanism of the Dictyostelium LRRK2 homolog Roco protein GbpC.

30 May 2018

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Somatostatin receptor 2 knockout/lacZ knockin mice show impaired motor coordination and reveal sites of somatostatin action within the striatum

30 May 2018

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Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein

30 May 2018

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Increased flexibility and selectivity in spatial learning of transgenic mice ectopically expressing the neural cell adhesion molecule L1 in astrocytes.

30 May 2018

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30 May 2018

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Isolated removal of hypothalamic or other brain nuclei of the rat

30 May 2018

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Genotypic differences in central neurotransmitter responses to aging in mice.

30 May 2018

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Behavior genetic analysis of mouse emotionality. III. The diallel analysis

30 May 2018

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Structural imaging in the presymptomatic stage of genetically determined parkinsonism.

30 May 2018

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Anxiety-dependent spatial navigation strategies in virtual and real spaces.

29 November 2018

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A novel transgenic mouse expressing double mutant tau driven by its natural promoter exhibits tauopathy characteristics.

29 November 2018

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Lrrk2-associated parkinsonism is a major cause of disease in Northern Spain

29 November 2018

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LRK-1, a C. elegans PARK8-related kinase, regulates axonal-dendritic polarity of SV proteins

29 November 2018

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Cognitive and affective aspects of thigmotaxis strategy in humans.

29 November 2018

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Anatomical localization of leucine-rich repeat kinase 2 in mouse brain

29 November 2018

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Altered depression-related behavior and neurochemical changes in serotonergic neurons in mutant R406W human tau transgenic mice

29 November 2018

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Dopamine in the medial prefrontal cortex controls genotype-dependent effects of amphetamine on mesoaccumbens dopamine release and locomotion

29 November 2018

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Specific tau phosphorylation sites correlate with severity of neuronal cytopathology in Alzheimer's disease.

29 November 2018

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Amphetamine distorts stimulation-dependent dopamine overflow: effects on D2 autoreceptors, transporters, and synaptic vesicle stores.

29 November 2018

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Striatal dopaminergic markers in dementia with Lewy bodies, Alzheimer's and Parkinson's diseases: rostrocaudal distribution.

29 November 2018

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Thigmotaxis as an index of anxiety in mice. Influence of dopaminergic transmissions.

29 November 2018

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Phosphorylated tau epitope of Alzheimer's disease is coupled to axon development in the avian central nervous system.

29 November 2018

1 reference

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Endogenous DA-mediated feedback inhibition of DA neurons: involvement of both D(1)- and D(2)-like receptors

29 November 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/20659558

12 December 2020

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3,4-Dihydroxyphenylacetic acid concentrations in the intermediate lobe and neural lobe of the posterior pituitary gland as an index of tuberohypophysial dopaminergic neuronal activity

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12 December 2020

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Phosphorylation determines two distinct species of Tau in the central nervous system.

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https://api.crossref.org/works/10.1016%2FJ.NBD.2010.07.010

7 January 2021

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Estimation of in-vivo neurotransmitter release by brain microdialysis

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https://api.crossref.org/works/10.1016%2FJ.NBD.2010.07.010

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1016/J.NBD.2010.07.010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20659558%20AND%20SRC:MED&resulttype=core&format=json

OpenCitations bibliographic resource ID

8 February 2020

1420131

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1420131

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20659558%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

1 reference