Rack1 binds HIV-1 Nef and can act as a Nef-protein kinase C adaptor (Q24291151)

positive regulation of protein phosphorylation

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

A Gallina

series ordinal

1

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F Rossi

series ordinal

2

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G Milanesi

series ordinal

3

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language of work or name

English

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publication date

25 April 2001

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number of pages

12

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Altered T cell activation and development in transgenic mice expressing the HIV-1 nef gene

inferred from page(s)

published in

Virology

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volume

283

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issue

1

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page(s)

7-18

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cites work

1 reference

https://api.crossref.org/works/10.1006%2FVIRO.2001.0855

7 January 2021

Proline-rich (PxxP) motifs in HIV-1 Nef bind to SH3 domains of a subset of Src kinases and are required for the enhanced growth of Nef+ viruses but not for down-regulation of CD4

1 reference

https://api.crossref.org/works/10.1006%2FVIRO.2001.0855

7 January 2021

The numerous effector functions of Nef.

1 reference

https://api.crossref.org/works/10.1006%2FVIRO.2001.0855

7 January 2021

A novel acyl-CoA thioesterase enhances its enzymatic activity by direct binding with HIV Nef

1 reference

https://api.crossref.org/works/10.1006%2FVIRO.2001.0855

7 January 2021

The growth advantage conferred by HIV-1 nef is determined at the level of viral DNA formation and is independent of CD4 downregulation.

1 reference

https://api.crossref.org/works/10.1006%2FVIRO.2001.0855

7 January 2021

Human immunodeficiency virus type I Nef independently affects virion incorporation of major histocompatibility complex class I molecules and virus infectivity

1 reference

https://api.crossref.org/works/10.1006%2FVIRO.2001.0855

7 January 2021

HsN3 proteasomal subunit as a target for human immunodeficiency virus type 1 Nef protein.

1 reference

https://api.crossref.org/works/10.1006%2FVIRO.2001.0855

7 January 2021

The human immunodeficiency virus type 1 Nef protein binds the Src-related tyrosine kinase Lck SH2 domain through a novel phosphotyrosine independent mechanism.

1 reference

https://api.crossref.org/works/10.1006%2FVIRO.2001.0855

7 January 2021

HIV-1 Nef plays an essential role in two independent processes in CD4 down-regulation: dissociation of the CD4-p56(lck) complex and targeting of CD4 to lysosomes.

1 reference

https://api.crossref.org/works/10.1006%2FVIRO.2001.0855

7 January 2021

Nef induces CD4 endocytosis: requirement for a critical dileucine motif in the membrane-proximal CD4 cytoplasmic domain

1 reference

https://api.crossref.org/works/10.1006%2FVIRO.2001.0855

7 January 2021

The structure of the G protein heterotrimer Gi alpha 1 beta 1 gamma 2

1 reference

https://api.crossref.org/works/10.1006%2FVIRO.2001.0855

7 January 2021

The HIV-1 nef gene acts as a positive viral infectivity factor

1 reference

https://api.crossref.org/works/10.1006%2FVIRO.2001.0855

7 January 2021

Identification and cloning of a novel cellular protein Naf1, Nef-associated factor 1, that increases cell surface CD4 expression

1 reference

https://api.crossref.org/works/10.1006%2FVIRO.2001.0855

7 January 2021

G protein heterodimers: new structures propel new questions

1 reference

https://api.crossref.org/works/10.1006%2FVIRO.2001.0855

7 January 2021

Crystal structure of the conserved core of HIV-1 Nef complexed with a Src family SH3 domain

1 reference

https://api.crossref.org/works/10.1006%2FVIRO.2001.0855

7 January 2021

HIV-1 auxiliary proteins: making connections in a dying cell.

1 reference

https://api.crossref.org/works/10.1006%2FVIRO.2001.0855

7 January 2021

Atomic structure of clathrin: a beta propeller terminal domain joins an alpha zigzag linker

1 reference

https://api.crossref.org/works/10.1006%2FVIRO.2001.0855

7 January 2021

Nef harbors a major determinant of pathogenicity for an AIDS-like disease induced by HIV-1 in transgenic mice

1 reference

https://api.crossref.org/works/10.1006%2FVIRO.2001.0855

7 January 2021

Importance of the pleckstrin homology domain of dynamin in clathrin-mediated endocytosis

1 reference

https://api.crossref.org/works/10.1006%2FVIRO.2001.0855

7 January 2021

HIV: a new role for Nef in the spread of HIV.

1 reference

https://api.crossref.org/works/10.1006%2FVIRO.2001.0855

7 January 2021

Inhibition of HIV-1 progeny virion release by cell-surface CD4 is relieved by expression of the viral Nef protein

1 reference

https://api.crossref.org/works/10.1006%2FVIRO.2001.0855

7 January 2021

Cell-surface expression of CD4 reduces HIV-1 infectivity by blocking Env incorporation in a Nef- and Vpu-inhibitable manner

1 reference

https://api.crossref.org/works/10.1006%2FVIRO.2001.0855

7 January 2021

Nef--an adaptor adaptor?

1 reference

https://api.crossref.org/works/10.1006%2FVIRO.2001.0855

7 January 2021

Modulating protein kinase C signal transduction.

1 reference

https://api.crossref.org/works/10.1006%2FVIRO.2001.0855

7 January 2021

Interactions between HIV1 Nef and vacuolar ATPase facilitate the internalization of CD4

1 reference

https://api.crossref.org/works/10.1006%2FVIRO.2001.0855

7 January 2021

Activation of Vav by Nef induces cytoskeletal rearrangements and downstream effector functions

1 reference

https://api.crossref.org/works/10.1006%2FVIRO.2001.0855

7 January 2021

p65 fragments, homologous to the C2 region of protein kinase C, bind to the intracellular receptors for protein kinase C

1 reference

https://api.crossref.org/works/10.1006%2FVIRO.2001.0855

7 January 2021

Folding of proteins with WD-repeats: comparison of six members of the WD-repeat superfamily to the G protein beta subunit.

1 reference

https://api.crossref.org/works/10.1006%2FVIRO.2001.0855

7 January 2021

RACK1, a protein kinase C anchoring protein, coordinates the binding of activated protein kinase C and select pleckstrin homology domains in vitro

1 reference

https://api.crossref.org/works/10.1006%2FVIRO.2001.0855

7 January 2021

HIV-1 Nef mediates lymphocyte chemotaxis and activation by infected macrophages

1 reference

https://api.crossref.org/works/10.1006%2FVIRO.2001.0855

7 January 2021

HIV-1 Nef protein binds to the cellular protein PACS-1 to downregulate class I major histocompatibility complexes

1 reference

https://api.crossref.org/works/10.1006%2FVIRO.2001.0855

7 January 2021

Serine phosphorylation-independent downregulation of cell-surface CD4 by nef

1 reference

https://api.crossref.org/works/10.1006%2FVIRO.2001.0855

7 January 2021

The ancient regulatory-protein family of WD-repeat proteins

1 reference

https://api.crossref.org/works/10.1006%2FVIRO.2001.0855

7 January 2021

New twists for dynamin

1 reference

https://api.crossref.org/works/10.1006%2FVIRO.2001.0855

7 January 2021

The solution structure of HIV-1 Nef reveals an unexpected fold and permits delineation of the binding surface for the SH3 domain of Hck tyrosine protein kinase

1 reference

https://api.crossref.org/works/10.1006%2FVIRO.2001.0855

7 January 2021

Association of RACK1 and PKCbeta with the common beta-chain of the IL-5/IL-3/GM-CSF receptor.

1 reference

https://api.crossref.org/works/10.1006%2FVIRO.2001.0855

7 January 2021

Physical linkage of a guanine nucleotide-binding protein-related gene to the chicken major histocompatibility complex

1 reference

https://api.crossref.org/works/10.1006%2FVIRO.2001.0855

7 January 2021

Phospholipase C-gamma 1 binding to intracellular receptors for activated protein kinase C

1 reference

https://api.crossref.org/works/10.1006%2FVIRO.2001.0855

7 January 2021

Cloning of an intracellular receptor for protein kinase C: a homolog of the beta subunit of G proteins

1 reference

https://api.crossref.org/works/10.1006%2FVIRO.2001.0855

7 January 2021

Human immunodeficiency virus type 1 Nef and p56lck protein-tyrosine kinase interact with a common element in CD4 cytoplasmic tail

1 reference

https://api.crossref.org/works/10.1006%2FVIRO.2001.0855

7 January 2021

An autoregulatory region in protein kinase C: the pseudoanchoring site

1 reference

https://api.crossref.org/works/10.1006%2FVIRO.2001.0855

7 January 2021

Nef proteins encoded by human and simian immunodeficiency viruses induce the accumulation of endosomes and lysosomes in human T cells

1 reference

https://api.crossref.org/works/10.1006%2FVIRO.2001.0855

7 January 2021

The Nef protein of HIV-1 associates with rafts and primes T cells for activation

1 reference

https://api.crossref.org/works/10.1006%2FVIRO.2001.0855

7 January 2021

Photolabeling of Prostaglandin Endoperoxide H Synthase-1 with 3-Trifluoro-3-(m-Iiodophenyl)diazirine as a Probe of Membrane Association and the Cyclooxygenase Active Site

1 reference

https://api.crossref.org/works/10.1006%2FVIRO.2001.0855

7 January 2021

Protein Kinase C-mediated Phosphorylation of HIV-I Nef in Human Cell Lines

1 reference

https://api.crossref.org/works/10.1006%2FVIRO.2001.0855

7 January 2021

Binding of HIV-1 Nef to a novel thioesterase enzyme correlates with Nef-mediated CD4 down-regulation

1 reference

https://api.crossref.org/works/10.1006%2FVIRO.2001.0855

7 January 2021

Rack1, a receptor for activated protein kinase C, interacts with integrin beta subunit

1 reference

https://api.crossref.org/works/10.1006%2FVIRO.2001.0855

7 January 2021

Photoinduced inactivation of protein kinase C by dequalinium identifies the RACK-1-binding domain as a recognition site

1 reference

https://api.crossref.org/works/10.1006%2FVIRO.2001.0855

7 January 2021

The RACK1 signaling scaffold protein selectively interacts with the cAMP-specific phosphodiesterase PDE4D5 isoform

1 reference

https://api.crossref.org/works/10.1006%2FVIRO.2001.0855

7 January 2021

Coordinated movement of RACK1 with activated betaIIPKC

1 reference

https://api.crossref.org/works/10.1006%2FVIRO.2001.0855

7 January 2021

Nef-mediated clathrin-coated pit formation

1 reference

https://api.crossref.org/works/10.1006%2FVIRO.2001.0855

7 January 2021

Induction of Fas ligand expression by HIV involves the interaction of Nef with the T cell receptor zeta chain

1 reference

https://api.crossref.org/works/10.1006%2FVIRO.2001.0855

7 January 2021

Separable functions of Nef disrupt two aspects of T cell receptor machinery: CD4 expression and CD3 signaling

1 reference

https://api.crossref.org/works/10.1006%2FVIRO.2001.0855

7 January 2021

Association of simian immunodeficiency virus Nef with the T-cell receptor (TCR) zeta chain leads to TCR down-modulation

1 reference

https://api.crossref.org/works/10.1006%2FVIRO.2001.0855

7 January 2021

Protein structural topology: Automated analysis and diagrammatic representation.

1 reference

https://api.crossref.org/works/10.1006%2FVIRO.2001.0855

7 January 2021

The downregulation of CD4 and MHC-I by primate lentiviruses: a paradigm for the modulation of cell surface receptors

1 reference

https://api.crossref.org/works/10.1006%2FVIRO.2001.0855

7 January 2021

RACK1, a receptor for activated C kinase and a homolog of the beta subunit of G proteins, inhibits activity of src tyrosine kinases and growth of NIH 3T3 cells

1 reference

https://api.crossref.org/works/10.1006%2FVIRO.2001.0855

7 January 2021